Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Susan Wiechert"'
Publikováno v:
Cell Reports, Vol 27, Iss 3, Pp 860-871.e8 (2019)
Summary: A truncating mutation in the mouse Srrm4 gene, which encodes a neuronal splicing factor, causes alternative splicing defects selectively in the ear. The mechanism by which splicing is preserved in the brain of these mice is not known. Here,
Externí odkaz:
https://doaj.org/article/e0b8d4cd693442d2bf46abd8b78c2e39
Publikováno v:
Life Science Alliance
The vital role of the splicing factor SRRM4 in vestibular and inner hair cells of the ear is inactivation of the gene repressor REST; however, in outer hair cells, SRRM4 is dispensable for REST inactivation, which SRRM3 accomplishes independently.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50e8c84e623ecf98b396993592d93971
http://europepmc.org/articles/PMC7652395
http://europepmc.org/articles/PMC7652395
Autor:
Susan Wiechert, Ann Tomanek-Chalkley, Jackie R. Bickenbach, Michael C. Winter, Sathivel Chinnathambi
Publikováno v:
The Journal of Dermatology. 39:617-624
Previously, we showed that transient transfection with OCT4 not only produced high expression of Oct4 in skin keratinocytes, but also caused a generalized demethylation of keratinocyte DNA. We hypothesized that DNA demethylation alone might allow exp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fbfa41dd62a12820b065478a2df3ccb7
https://doi.org/10.1111/j.1346-8138.2012.01553.x
https://doi.org/10.1111/j.1346-8138.2012.01553.x
Autor:
Sathivel, Chinnathambi, Susan, Wiechert, Ann, Tomanek-Chalkley, Michael C, Winter, Jackie R, Bickenbach
Publikováno v:
The Journal of dermatology. 39(7)
Previously, we showed that transient transfection with OCT4 not only produced high expression of Oct4 in skin keratinocytes, but also caused a generalized demethylation of keratinocyte DNA. We hypothesized that DNA demethylation alone might allow exp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d1b06c92bf5e0b8b00ac36a85a6c53f9
https://pubmed.ncbi.nlm.nih.gov/22486352
https://pubmed.ncbi.nlm.nih.gov/22486352
Autor:
Susan Wiechert, Ann Tomanek-Chalkley, Doina Racila, Michael C. Winter, Richard L. Eckert, Mohammed Said, Jackie R. Bickenbach
Publikováno v:
Gene therapy
In this study, we describe a simple system in which human keratinocytes can be redirected to an alternative differentiation pathway. We transiently transfected freshly isolated human skin keratinocytes with the single transcription factor OCT4. Withi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2a94005a1493d142083c4d990d0aca1
https://pubmed.ncbi.nlm.nih.gov/20981110
https://pubmed.ncbi.nlm.nih.gov/20981110
Autor:
Nukhet Aykin-Burns, Susan Wiechert, Caitlin Cloud, Jackie R. Bickenbach, Ann Tomanek-Chalkley
Publikováno v:
The FASEB Journal. 24
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ce2bc54b7e527c48729f4ef981a460a3
https://doi.org/10.1096/fasebj.24.1_supplement.402.1
https://doi.org/10.1096/fasebj.24.1_supplement.402.1
Autor:
Robert T. Cook, Nancy B. Ray, Susan Wiechert, Kevin L. Legge, Thomas J. Waldschmidt, Lucas E. Turner, Betty M. Young, Ruth A. Coleman, Prajwal Gurung
Chronic ethanol consumption results in immunodeficiency. Previous work with chronic ethanol-fed mice has shown reduced splenic weight and cellularity, including reduced numbers of CD8+ T cells. However, antigen-specific CD8+ and CD4+ T cell responses
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7fd5d75720877cfa20b4aa973f4ac13
https://europepmc.org/articles/PMC2626766/
https://europepmc.org/articles/PMC2626766/
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 447
Evaluation of the functional responses of T cells is of importance in determining the mechanism(s) of immunodeficiency resulting from chronic alcohol abuse and other conditions that lead to immune dysfunction. Mice that are chronically exposed to 20%
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9b61114afd3b12cc654c89a320d8f913
https://pubmed.ncbi.nlm.nih.gov/18369925
https://pubmed.ncbi.nlm.nih.gov/18369925
Publikováno v:
Alcohol ISBN: 9781588299062
Evaluation of the functional responses of T cells is of importance in determining the mechanism(s) of immunodeficiency resulting from chronic alcohol abuse and other conditions that lead to immune dysfunction. Mice that are chronically exposed to 20%
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::25cbaa6a79632434fcc45fdcf2199d3d
https://doi.org/10.1007/978-1-59745-242-7_19
https://doi.org/10.1007/978-1-59745-242-7_19
Autor:
Prajwal Gurung, Betty M Young, Lucas E Turner, Ruth A Coleman, Susan Wiechert, Thomas J Waldschmidt, Kevin L Legge, Robert T Cook
Publikováno v:
The Journal of Immunology. 182:129.17-129.17
Chronic ethanol consumption leads to increased translocation of bacterial products such as LPS and PGN. Previously, we have shown that chronic ethanol consumption results in reduced antigen-specific CD8+ T cell responses following attenuated Listeria
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5f1bee8286846de919ab5e7ae690a8a9
https://doi.org/10.4049/jimmunol.182.supp.129.17
https://doi.org/10.4049/jimmunol.182.supp.129.17