Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Susan W. Sunnarborg"'
Autor:
Akiko Yagami, Naoki Kajiwara, Keisuke Oboki, Tatsukuni Ohno, Hideaki Morita, Susan W Sunnarborg, Ko Okumura, Hideoki Ogawa, Hirohisa Saito, Susumu Nakae
Publikováno v:
Allergology International, Vol 59, Iss 3, Pp 277-284 (2010)
ABSTRACT: Background: Amphiregulin (AR) is expressed in Th2 cells, rather than Th1 cells, and plays an important role in Th2 cell/cytokine-mediated host defense against nematodes. We also found earlier that AR mRNA expression was strongly upregulated
Externí odkaz:
https://doaj.org/article/f43536ca82ad4cacb13e403770b5c2f9
Publikováno v:
Nanomedicine. 6:19-24
The Carolina Center of Cancer Nanotechnology Excellence (C-CCNE) is funded by the National Cancer Institute and is based at the University of North Carolina. The C-CCNE features interactions between physical and biological scientists in a series of p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fcbd85838285e1b6b9c9de15d811f781
https://doi.org/10.2217/nnm.10.142
https://doi.org/10.2217/nnm.10.142
Autor:
Rutger J. Ploeg, Harry van Goor, Henri G. D. Leuvenink, Niels J. Kloosterhuis, Susan W. Sunnarborg, Eelke M. Bos, Wynand B. W. H. Melenhorst, Robert H. Henning, Marc A. Seelen, Willemijn N. Nijboer, Lydia Visser, Maria Sandovici, Monika Trzpis, Gemma M. Mulder
Publikováno v:
The Journal of Pathology. 221:183-192
The epidermal growth factor (EGF) receptor and its ligands are crucially involved in the renal response to ischaemia. We studied the heparin binding-epidermal growth factor (HB-EGF), a major ligand for the EGF receptor, in experimental and human isch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e1b7cadb583afc4b782b65064ce4af30
https://doi.org/10.1002/path.2698
https://doi.org/10.1002/path.2698
Autor:
Keisuke Oboki, Hirohisa Saito, Susan W. Sunnarborg, Akina Ishii, Susumu Nakae, Tatsukuni Ohno, Ko Okumura, Naoki Kajiwara
Publikováno v:
Allergology International. 59:207-211
Background: The number of amphiregulin (AR)-positive mast cells in the bronchial mucosa and the levels of AR in sputum from asthmatic patients have been reported to be increased. In addition, AR can promote mucin gene expression in human epithelial c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27f89832a97a8b46026644948a0ae4cb
https://doi.org/10.2332/allergolint.09-oa-0144
https://doi.org/10.2332/allergolint.09-oa-0144
Autor:
Stefano Rizza, Marta Letizia Hribal, Domenico Accili, Rama Khokha, Alessandro Mauriello, Hiroko Kanno, Matteo Serino, Ottavia Porzio, David C. Lee, Renato Lauro, Giorgio Sesti, Paolo Sbraccia, Valentina Marchetti, Veronica Cunsolo, David Smookler, Susan W. Sunnarborg, Massimo Federici, Rossella Menghini, Davide Lauro
Publikováno v:
Journal of Clinical Investigation. 115:3494-3505
Activation of inflammatory pathways may contribute to the beginning and the progression of both atherosclerosis and type 2 diabetes. Here we report a novel interaction between insulin action and control of inflammation, resulting in glucose intoleran
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::360973534bcf665e1da8400cf18be64e
https://doi.org/10.1172/jci26052
https://doi.org/10.1172/jci26052
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 25:1884-1890
Objective— Heparin-binding epidermal growth factor–like growth factor (HB-EGF) is a potent mitogen for smooth muscle cells and has been implicated in atherosclerosis, tissue regeneration after ischemia, vascular development, and tumor angiogenesi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::737e8b2acb981d71fa89971715055d75
https://doi.org/10.1161/01.atv.0000175761.59602.16
https://doi.org/10.1161/01.atv.0000175761.59602.16
Autor:
Carol E. Parker, Mary C. Stevenson, C. Leann Hinkle, Susan W. Sunnarborg, David C. Lee, William E. Russell, David R. Loiselle
Publikováno v:
Journal of Biological Chemistry. 279:24179-24188
Epidermal growth factor (EGF) family ligands are derived by proteolytic cleavage of the ectodomains of integral membrane precursors. Previously, we established that tumor necrosis factor α-converting enzyme (TACE/ADAM17) is a physiologic transformin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0877f331428d5737ce4ada741ec2b842
https://doi.org/10.1074/jbc.m312141200
https://doi.org/10.1074/jbc.m312141200
Autor:
John R. Doedens, Beverly J Castner, Guixian Jin, Susan W. Sunnarborg, Roy A. Black, R. Cowling, Jennifer L. Slack, Richard S. Johnson, Keith Charrier, Ray Paxton, Duke Virca, David C. Lee, Lin Guo, Alison Wallace, Jacques J. Peschon, Rajeev M Mahimkar, June R. Eisenman
Publikováno v:
Biochemical Society Symposia. 70:39-52
Tumour necrosis factor α (TNFα)-converting enzyme (TACE/ADAM-17, where ADAM stands for a disintegrin and metalloproteinase) releases from the cell surface the extracellular domains of TNF and several other proteins. Previous studies have found that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9727d6426c1d576731fc2cee98f33d8
https://doi.org/10.1042/bss0700039
https://doi.org/10.1042/bss0700039
Autor:
C. Leann Hinkle, William E. Russell, Timothy J. Myers, David C. Lee, Leslie F. Jackson, Aileen Chang, Raymond J. Paxton, Roy A. Black, Mary Y Stevenson, Mary Gerhart, Beverly J Castner, Susan W. Sunnarborg
Publikováno v:
Annals of the New York Academy of Sciences. 995:22-38
EGF family growth factors, including transforming growth factor-alpha (TGFalpha), amphiregulin (AR), and heparin-binding EGF (HB-EGF), are invariably expressed as transmembrane precursors that are cleaved at one or more sites in the extracellular dom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32c88e372be78eacdeab97934416a9b2
https://doi.org/10.1111/j.1749-6632.2003.tb03207.x
https://doi.org/10.1111/j.1749-6632.2003.tb03207.x
Autor:
Zhongjun Zhou, Falk Fahrenholz, Susan W. Sunnarborg, Leena Bruckner-Tuderman, David C. Lee, Claus-Werner Franzke, Cornelia Mauch, Paola Zigrino, Kaisa Tasanen, Heike Schäcke, Karl Tryggvason
Publikováno v:
The EMBO Journal. 21:5026-5035
Collagen XVII, a type II transmembrane protein and epithelial adhesion molecule, can be proteolytically shed from the cell surface to generate a soluble collagen. Here we investigated the release of the ectodomain and identified the enzymes involved.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b1eac797ffe737231c1ac7c402c5eee
https://doi.org/10.1093/emboj/cdf532
https://doi.org/10.1093/emboj/cdf532