Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Susan W. S. Leung"'
Publikováno v:
Frontiers in Medicine, Vol 8 (2021)
The prevalence of diabetes is consistently rising worldwide. Diabetic nephropathy is a leading cause of chronic renal failure. The present study aimed to explore the crosstalk among the different cell types inside diabetic glomeruli, including glomer
Externí odkaz:
https://doaj.org/article/65665a7517114c03be033eb75c74e1d9
Autor:
Harry W. Pan, Han Cong Seow, Jason C. K. Lo, Jinlin Guo, Lingqiao Zhu, Susan W. S. Leung, Chenghai Zhang, Jenny K. W. Lam
Publikováno v:
Pharmaceutical Research. 39:2291-2304
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9d81442549459498c7a2079499da1669
https://doi.org/10.1007/s11095-022-03331-w
https://doi.org/10.1007/s11095-022-03331-w
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 4, Iss C (2015)
Discovered a little over two decades ago, small interfering RNAs (siRNAs) and microRNAs (miRNAs) are noncoding RNAs with important roles in gene regulation. They have recently been investigated as novel classes of therapeutic agents for the treatment
Externí odkaz:
https://doaj.org/article/b369c0cf33a24f45a87721ce4a2698f5
Autor:
Amanda H Y Lin, Rachel W S Li, Eva Y W Ho, George P H Leung, Susan W S Leung, Paul M Vanhoutte, Ricky Y K Man
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e63199 (2013)
Rapid non-genomic effects of 17β-estradiol are elicited by the activation of different estrogen receptor-α isoforms. Presence of surface binding sites for estrogen have been identified in cells transfected with full-length estrogen receptor-α66 (E
Externí odkaz:
https://doaj.org/article/92b20d56ea004f4a8e31b58a69038324
Publikováno v:
Molecules, Vol 21, Iss 9, p 1249 (2016)
RNA interference (RNAi) is a potent and specific post-transcriptional gene silencing process. Since its discovery, tremendous efforts have been made to translate RNAi technology into therapeutic applications for the treatment of different human disea
Externí odkaz:
https://doaj.org/article/5a3692a529cb40ca8140a7a2516307bf
Autor:
Susan W S Leung
Publikováno v:
Acta physiologica (Oxford, England)REFERENCES. 231(2)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87af9d53f6b5983e81e0470ee6549d4c
https://pubmed.ncbi.nlm.nih.gov/32886850
https://pubmed.ncbi.nlm.nih.gov/32886850
Publikováno v:
American journal of physiology. Heart and circulatory physiology. 314(3)
Hypertension is associated with endothelial dysfunction, which favors the release of endothelium-derived contracting factors, including vasoconstrictor prostanoids and reactive oxygen species. Peroxisome proliferator-activated receptor-α (PPAR-α) a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e9f5f799138640a2a90ae1dedb20436e
https://pubmed.ncbi.nlm.nih.gov/29127234
https://pubmed.ncbi.nlm.nih.gov/29127234
Publikováno v:
Handbook of experimental pharmacology. 238
Traditionally, only the 3',5'-cyclic monophosphates of adenosine and guanosine (produced by adenylyl cyclase and guanylyl cyclase, respectively) are regarded as true "second messengers" in the vascular wall, despite the presence of other cyclic nucle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e2b443eabf04e75c2d210450f8e1b792
https://pubmed.ncbi.nlm.nih.gov/26721675
https://pubmed.ncbi.nlm.nih.gov/26721675
Publikováno v:
Pharmacology. 69:164-170
The hemodynamic effects of NG-nitro-L-arginine methyl ester (L-NAME, inhibitor of nitric oxide (NO) synthase) were examined in thiobutabarbital-anesthetized controlrats and rats with monocrotaline-induced pulmonary hypertension. L-NAME (1–16 mg/kg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ebef84365d0c0f724ed1c4aea8985b4c
https://doi.org/10.1159/000072670
https://doi.org/10.1159/000072670
Autor:
Ricky Y K, Man, Susan W S, Leung
Publikováno v:
Clinical and experimental pharmacologyphysiology. 34(8)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d2cb179d219a060f32fa38966b5a4830
https://pubmed.ncbi.nlm.nih.gov/17600561
https://pubmed.ncbi.nlm.nih.gov/17600561