Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Susan Valmadre"'
Autor:
Jean Yang, Susan Valmadre, Jaynish S. Shah, Gregory B. Gard, Deborah J. Marsh, Patsy S. Soon, Jayne Maidens
Publikováno v:
Gynecologic Oncology. 148:181-188
© 2017 Elsevier Inc. Objectives The most widely used approach for the clinical management of women with high-grade serous ovarian cancer (HGSOC) is surgery, followed by platinum and taxane based chemotherapy. The degree of macroscopic disease remain
Autor:
Ying Zhu, Alexander J. Cole, Deborah J. Marsh, Jayne Maidens, Gregory B. Gard, Kristie-Ann Dickson, Bing Yu, Anthony J. Gill, Roderick J. Clifton-Bligh, Trisha Dwight, Susan Valmadre
Publikováno v:
Scientific Data
Somatic mutation of the tumor suppressor gene TP53 is reported in at least 50% of human malignancies. Most high-grade serous ovarian cancers (HGSC) have a mutant TP53 allele. Accurate detection of these mutants in heterogeneous tumor tissue is paramo
Autor:
Trisha Dwight, Susan Valmadre, Adele Clarkson, Alexander J. Cole, Jayne Maidens, Gregory B. Gard, Deborah J. Marsh, Kristie-Ann Dickson, Ying Zhu, Roderick J. Clifton-Bligh, Anthony J. Gill
Publikováno v:
Scientific Reports
The tumour suppressor p53 is mutated in cancer, including over 96% of high-grade serous ovarian cancer (HGSOC). Mutations cause loss of wild-type p53 function due to either gain of abnormal function of mutant p53 (mutp53), or absent to low mutp53. Ma
Publikováno v:
Gynecologic Oncology Case Reports. 2:121-123
Adjuvant intravaginal brachytherapy (IVBT) is an evidenced-based strategy that significantly reduces the long-term rate of post-hysterectomy vaginal mucosal relapse in women with intermediate and high-risk endometrial cancer (EC) (Nout et al., 2010).
Autor:
Peter Russell, Perapong Inthasorn, Jonathan Carter, Christopher Dalrymple, Susan Valmadre, Philip Beale
Publikováno v:
International Journal of Gynecological Cancer. 12:348-353
The aim of this study was to retrospectively analyze the clinical and pathologic data of a series of patients presenting to our unit with uterine malignant mixed Mullerian tumors (MMMT) to attempt to identify prognostic factors and relate them to sur
Publikováno v:
Pathology. 42:483-485
Sir,Simulacra are the bane of the unwary pathologist's life, sometimes with non-trivial clinical or ‘social’ consequences for the patient, from a wrong diagnosis. Epidermolytic hyperkeratosis (EHK)...
Publikováno v:
Pathology. 42:95-97
Sir,Endometriosis is a common disorder of women in their reproductive years and pathologists generally have few problems diagnosing characteristic cases. Diagnosis becomes occasionally more challen...
Publikováno v:
Pathology. 34:197-199
Autor:
Alexander J. Cole, Anthony J. Gill, Gregory B. Gard, Roderick J. Clifton-Bligh, Deborah J. Marsh, Adele Clarkson, Kristie-Ann Dickson, Jayne Maidens, Ying Zhu, Trisha Dwight, Susan Valmadre
Publikováno v:
Clinical Cancer Research. 22:B05-B05
Mutations in TP53 have been shown to occur in around 96% of high-grade serous ovarian cancer (HGSOC). Different TP53 mutations can lead to accumulation of mutant p53 in the cell that support gain of function effects, or loss or abrogation of both wil
Autor:
R. Houghton, Peter Russell, Paul R. McKenzie, K. Atkinson, Jonathan Carter, Susan Valmadre, Christopher Dalrymple
Publikováno v:
Scopus-Elsevier
Objective The National Health and Medical Research Council (NHMRC) recommends a report of ‘inconclusive - possible high grade epithelial abnormality’, but many laboratories only report ‘inconclusive’ with reference to any possible high grade