Zobrazeno 1 - 10
of 141
pro vyhledávání: '"Susan V. Mclennan"'
Publikováno v:
Pathophysiology, Vol 29, Iss 4, Pp 640-649 (2022)
Transforming growth factor beta (TGFβ) is a versatile cytokine. Although a profibrotic role of TGFβ is well established, its effect on tissue inhibitor of metalloproteinase (TIMPs) and inflammatory mediators are incompletely described. This study i
Externí odkaz:
https://doaj.org/article/b47f6226446c4a728c748ae5b45a6e2b
Autor:
Babu R. Maharjan, Sergio F. Martinez‐Huenchullan, Susan V. Mclennan, Stephen M. Twigg, Paul F. Williams
Publikováno v:
Physiological Reports, Vol 9, Iss 16, Pp n/a-n/a (2021)
Abstract Diet and/or exercise are cost effective interventions to treat obesity. However, it is unclear if the type of exercise undertaken can prevent the onset of obesity and if it can act through different effects on fat depots. In this study we di
Externí odkaz:
https://doaj.org/article/8384163893d949cea71913a6a28e6b60
Publikováno v:
Molecules, Vol 27, Iss 3, p 727 (2022)
A diet-induced non-alcoholic fatty liver disease (NAFLD) model causing obesity in rodents was used to examine whether sitagliptin and gliclazide therapies have similar protective effects on pathological liver change. Methods: Male mice were fed a hig
Externí odkaz:
https://doaj.org/article/e55ade62bcc44c508a14b5a414d655f4
Autor:
Albert Hsieh, Stephen Adelstein, Susan V. McLennan, Paul F. Williams, Elizabeth L. Chua, Stephen M. Twigg
Publikováno v:
Endocrinology, Diabetes & Metabolism, Vol 2, Iss 4, Pp n/a-n/a (2019)
Abstract Objective To investigate the associations of Graves' disease (GD) severity, autoimmunity and longitudinal liver enzyme changes with time in a cohort with well‐characterized GD. Design Retrospective cohort study. Patients Patients diagnosed
Externí odkaz:
https://doaj.org/article/d7b7251c93714c26a72b3675340fb488
Autor:
Sergio F. Martinez-Huenchullan, Linda A. Ban, Luisa F. Olaya-Agudo, Babu Raja Maharjan, Paul F. Williams, Charmaine S. Tam, Susan V. Mclennan, Stephen M. Twigg
Publikováno v:
Frontiers in Physiology, Vol 10 (2019)
In a mouse model of diet-induced obesity, this study determined if two exercise prescriptions with equivalent time and distance covered, [constant-moderate endurance (END) and high intensity interval training (HIIT)], exert differential metabolic ben
Externí odkaz:
https://doaj.org/article/b1b2554392de4fa49fc2a687b79d5e30
Autor:
Kristine C. McGrath, Xiao Hong Li, Phillippa T. Whitworth, Robert Kasz, Joanne T. Tan, Susan V. McLennan, David S. Celermajer, Philip J. Barter, Kerry-Anne Rye, Alison K. Heather
Publikováno v:
Journal of Lipid Research, Vol 55, Iss 3, Pp 421-430 (2014)
Obesity-induced liver inflammation can drive insulin resistance. HDL has anti-inflammatory properties, so we hypothesized that low levels of HDL would perpetuate inflammatory responses in the liver and that HDL treatment would suppress liver inflamma
Externí odkaz:
https://doaj.org/article/d032a1ba13d04a80aeaff1092ca2a961
Autor:
Fiona M. Keane, Tsun-Wen Yao, Stefanie Seelk, Margaret G. Gall, Sumaiya Chowdhury, Sarah E. Poplawski, Jack H. Lai, Youhua Li, Wengen Wu, Penny Farrell, Ana Julia Vieira de Ribeiro, Brenna Osborne, Denise M.T. Yu, Devanshi Seth, Khairunnessa Rahman, Paul Haber, A. Kemal Topaloglu, Chuanmin Wang, Sally Thomson, Annemarie Hennessy, John Prins, Stephen M. Twigg, Susan V. McLennan, Geoffrey W. McCaughan, William W. Bachovchin, Mark D. Gorrell
Publikováno v:
FEBS Open Bio, Vol 4, Iss C, Pp 43-54 (2014)
The protease fibroblast activation protein (FAP) is a specific marker of activated mesenchymal cells in tumour stroma and fibrotic liver. A specific, reliable FAP enzyme assay has been lacking. FAP's unique and restricted cleavage of the post proline
Externí odkaz:
https://doaj.org/article/699a5667312a445ea11703a45af02b69
Autor:
Danqing Min, Belinda Brooks, Jencia Wong, Robert Salomon, Wensheng Bao, Brian Harrisberg, Stephen M. Twigg, Dennis K. Yue, Susan V. McLennan
Publikováno v:
Mediators of Inflammation, Vol 2012 (2012)
Monocytes express many cell surface markers indicative of their inflammatory and activation status. Whether these markers are affected by diabetes and its complications is not known and was investigated in this study. Blood was obtained from 22 nondi
Externí odkaz:
https://doaj.org/article/47ffae53d75f4324b2252bebc4e1e771
Autor:
Jing Ren, Xiaoyu Wang, Sarah N. Parry, Christine Yee, Mark D. Gorrell, Susan V. McLennan, Stephen M. Twigg
Publikováno v:
Journal of Cell Communication and Signaling. 16:447-460
Type 2 diabetes is an independent risk factor for non-alcoholic steatohepatitis (NASH) progression and its mediators have not been resolved. In this study, a pathogenic role of cellular communication network factor 2 (CCN2) protein in NASH pathology,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7983dcff9d6ff8b9b97e29e2a5ab9c0f
https://doi.org/10.1007/s12079-022-00667-1
https://doi.org/10.1007/s12079-022-00667-1
Autor:
Sergio F. Martinez-Huenchullan, Luisa F. Olaya-Agudo, Stephen M. Twigg, Paul F. Williams, Charmaine S. Tam, Pamela Ehrenfeld, Babu Raja Maharjan, Sarah L Fox, Susan V. McLennan
Publikováno v:
Archives of Physiology and Biochemistry. 129:41-45
Research has described that adiponectin plays a key role in cardiomyocytes metabolism, however, the effects of exercise during obesity on cardiac adiponectin levels is unclear.To investigate the effects of constant-moderate endurance (END) and high-i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b22dc884fc007543486356cb1c331395
https://doi.org/10.1080/13813455.2020.1797098
https://doi.org/10.1080/13813455.2020.1797098