Zobrazeno 1 - 10
of 422
pro vyhledávání: '"Susan Tsai"'
Autor:
Maahum Mehdi, Aniko Szabo, Aditya Shreenivas, James P. Thomas, Susan Tsai, Kathleen K. Christians, Douglas B. Evans, Callisia N. Clarke, William A. Hall, Beth Erickson, Gulrayz Ahmed, Bicky Thapa, Thomas McFall, Ben George, Razelle Kurzrock, Mandana Kamgar
Publikováno v:
Therapeutic Advances in Medical Oncology, Vol 16 (2024)
Background: KRAS wild-type (WT) pancreatic ductal adenocarcinoma (PDAC) represents a distinct entity with unique biology. The therapeutic impact of matched targeted therapy in these patients in a real-world setting, to date, is less established. Obje
Externí odkaz:
https://doaj.org/article/bd7894590ed34775a299046ba503207e
Autor:
Saryleine deOrtiz de Choudens, Alexis Visotcky, Anjishnu Banerjee, Mohammed Aldakkak, Susan Tsai, Douglas B. Evans, Kathleen K. Christians, Callisia N. Clarke, Ben George, Aditya Shreenivas, Mandana Kamgar, Sakti Chakrabarti, Kulwinder S. Dua, Abdul Haq Khan, Srivats Madhavan, Beth A. Erickson, William A. Hall
Publikováno v:
Cancer Medicine, Vol 13, Iss 1, Pp n/a-n/a (2024)
Abstract Purpose/Objectives Most patients with pancreatic adenocarcinoma (PDAC) will present with distant metastatic disease at diagnosis. We sought to identify clinical characteristics associated with prolonged overall survival (OS) in patients pres
Externí odkaz:
https://doaj.org/article/d0a3e59b182b4d1c8f7d23ee7bc3a49f
Autor:
Gopika SenthilKumar, Sharadhi Madhusudhana, Madelyn Flitcroft, Salma Sheriff, Samih Thalji, Jennifer Merrill, Callisia N. Clarke, Ugwuji N. Maduekwe, Susan Tsai, Kathleen K. Christians, T. Clark Gamblin, Anai N. Kothari
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract Early postoperative mortality risk prediction is crucial for clinical management of gastric cancer. This study aims to predict 90-day mortality in gastric cancer patients undergoing gastrectomy using automated machine learning (AutoML), opti
Externí odkaz:
https://doaj.org/article/b28725a210ed48cc8d0ba154d506909c
Autor:
Husain Yar Khan, PhD, Mandana Kamgar, MD, Amro Aboukameel, MS, Sahar Bannoura, MS, Brian Y. Chung, PhD, Yiwei Li, MD, Mohammed Najeeb Al Hallak, MD, Philip A. Philip, MD, PhD, Susan Tsai, MD, Sanjeev Luther, MBA, William A. Hall, MD, Asfar S. Azmi, PhD
Publikováno v:
Advances in Radiation Oncology, Vol 8, Iss 1, Pp 101122- (2023)
Purpose: Local tumor progression is a cause of significant morbidity and mortality in patients with pancreatic ductal adenocarcinoma (PDAC) with surgically unresectable disease. Novel and effective approaches to accomplish durable local control are u
Externí odkaz:
https://doaj.org/article/ee77f111869b4d7c8620b432196590f6
Publikováno v:
npj Precision Oncology, Vol 5, Iss 1, Pp 1-7 (2021)
Abstract Pancreatic cancer (PC) is notoriously difficult to diagnosis and properly stage resulting in incorrect primary treatment. Diagnostic and prognostic biomarkers are desperately needed to more accurately stage patients and select proper treatme
Externí odkaz:
https://doaj.org/article/2584944841bc4ed8b933510f4a3fd00a
Autor:
Dimpal M. Kasabwala, Raymond C. Bergan, Kirby P. Gardner, Rena Lapidus, Susan Tsai, Mohammed Aldakkak, Daniel L. Adams
Publikováno v:
Biomedicines, Vol 10, Iss 11, p 2898 (2022)
Micronuclei (MN) are fragments of damaged nucleic acids which budded from a cell’s nuclei as a repair mechanism for chromosomal instabilities, which within circulating white blood cells (cWBCs) signifies increased cancer risk, and in tumor cells in
Externí odkaz:
https://doaj.org/article/962e79c584dd4b62880113fa59cb014f
Publikováno v:
PLoS ONE, Vol 17, Iss 3 (2022)
The aggressive nature and metastatic potential of pancreatic cancer (PC) results in poor prognosis and high mortality. A better understanding of the underlying biology of PC and the ability of tumor cells to spread to distant sites is needed to advan
Externí odkaz:
https://doaj.org/article/a3a399881d2e48089911c96e03b0159e
Autor:
Pan Pan, Zheng Zhu, Kiyoko Oshima, Mohammed Aldakkak, Susan Tsai, Yi‐Wen Huang, Wenjuan Dong, Jianying Zhang, Chien‐Wei Lin, Youwei Wang, Martha Yearsley, Jianhua Yu, Li‐Shu Wang
Publikováno v:
Food Frontiers, Vol 1, Iss 1, Pp 70-82 (2020)
Abstract Pancreatic ductal adenocarcinoma (PDAC) is a fatal disease with a low survival rate (9%). Epidemiologic studies show that healthy dietary patterns enriched of fruits and vegetables lower the risk of PDAC. We previously showed that supplement
Externí odkaz:
https://doaj.org/article/2ef0227ceef94eec952a0271cd027fbc
Autor:
Michael T. Zimmermann, Angela J. Mathison, Tim Stodola, Douglas B. Evans, Jenica L. Abrudan, Wendy Demos, Michael Tschannen, Mohammed Aldakkak, Jennifer Geurts, Gwen Lomberk, Susan Tsai, Raul Urrutia
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
We investigated germline variation in pancreatic ductal adenocarcinoma (PDAC) predisposition genes in 535 patients, using a custom-built panel and a new complementary bioinformatic approach. Our panel assessed genes belonging to DNA repair, cell cycl
Externí odkaz:
https://doaj.org/article/3d3e3ba3fdb348329ad902d23823b3af
Autor:
Yi-Wen Huang, Chien-Wei Lin, Pan Pan, Tianjiao Shan, Carla Elena Echeveste, Yue Yang Mo, Hsin-Tzu Wang, Mohammed Aldakkak, Susan Tsai, Kiyoko Oshima, Martha Yearsley, Jianbo Xiao, Hui Cao, Chongde Sun, Ming Du, Weibin Bai, Jianhua Yu, Li-Shu Wang
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Innate immune cells in the tumor microenvironment have been proposed to control the transition from benign to malignant stages. In many cancers, increased infiltration of natural killer (NK) cells associates with good prognosis. Although the mechanis
Externí odkaz:
https://doaj.org/article/461b11582796451d91563da32754c5cf