Výsledky vyhledávání - "Susan T. Varghese"

Metabolic stress, reactive oxygen species, and arrhythmia

Autor: Samuel C. Dudley, Megan Sturdy, Ge Gao, Euy Myoung Jeong, Man Liu, Ali A. Sovari, Susan T Varghese

Publikováno v: Journal of Molecular and Cellular Cardiology. 52:454-463

Cardiac arrhythmias can cause sudden cardiac death (SCD) and add to the current heart failure (HF) health crisis. Nevertheless, the pathological processes underlying arrhythmias are unclear. Arrhythmic conditions are associated with systemic and card

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d61bd65400f1475839331254334300f5
https://doi.org/10.1016/j.yjmcc.2011.09.018

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Abstract 186: AMP-Activated Protein Kinase Mediates Cardioprotection in the Regenerative MRL Mouse Strain

Autor: Susan T Varghese, Jenan Holley-Cuthrell, Chad M Warren, Ann Kuenster, Ahlke Heydemann

Publikováno v: Circulation Research. 111

Introduction: The Murphy Roths Large (MRL/MpJ) mouse model is well-known for its healing and regenerative properties. The actual mechanisms promoting regeneration are still unknown. AMP activated protein kinase (AMPK) has been lauded for its role as

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::de68f84465de0ed2402d19b256250540
https://doi.org/10.1161/res.111.suppl_1.a186

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Abstract P081: Voltage-Gated TTX-Sensitive Nav1.1 Brain Sodium Channels Are Important for Cardiac Contractile Function

Autor: Andrew Escayg, Stephanie Humphrey, Samuel C. Dudley, An Xie, Susan T Varghese

Publikováno v: Circulation Research. 109

Background: Mutations in voltage gated brain sodium channel Nav1.1 have been linked to many disorders, including Generalized Epilepsy with Febrile Seizures Plus (GEFS+) and Severe Myoclonic Epilepsy of Infancy (SMEI). Recent studies have identified T

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fdfa76c9cd597bed6daa705968a96b1e
https://doi.org/10.1161/res.109.suppl_1.ap081

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Temporal effects of catalase overexpression on healing after myocardial infarction

Autor: Michael Davis, Kathryn Maiellaro-Rafferty, Susan T. Varghese, Milton E. Brown, Karl D. Pendergrass, W. Robert Taylor

Publikováno v: Circulation. Heart failure. 4(1)

Background— Reactive oxygen species, such as hydrogen peroxide (H 2 O 2 ), contribute to progression of dysfunction after myocardial infarction (MI). However, chronic overexpression studies do not agree with acute protein delivery studies. The purp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a20f9369138814eae19abe2bd6c4b873
https://pubmed.ncbi.nlm.nih.gov/20971939

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