Zobrazeno 1 - 10
of 82
pro vyhledávání: '"Susan T. Sharfstein"'
Autor:
Eziafa I. Oduah, Susan T. Sharfstein, Nagashree Seetharamu, Steven R. Grossman, Larisa Litovchick
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
Lung cancer is the leading cause of cancer mortality. Despite therapeutic advances in recent years, new treatment strategies are needed to improve outcomes of lung cancer patients. Mutant p53 is prevalent in lung cancers and drives several hallmarks
Externí odkaz:
https://doaj.org/article/63643ce1db2d4af797061ae9c1eb030d
Autor:
Sujith Chander Reddy Kollampally, Xulang Zhang, Nicholas Moskwa, Deirdre A. Nelson, Susan T. Sharfstein, Melinda Larsen, Yubing Xie
Publikováno v:
Bioengineering, Vol 11, Iss 4, p 375 (2024)
Mesenchymal stromal cells (MSCs) have displayed potential in regenerating organ function due to their anti-fibrotic, anti-inflammatory, and regenerative properties. However, there is a need for delivery systems to enhance MSC retention while maintain
Externí odkaz:
https://doaj.org/article/944303c647804df080d08f457574e870
Publikováno v:
Bioengineering, Vol 11, Iss 1, p 28 (2023)
Salivary gland dysfunction affects millions globally, and tissue engineering may provide a promising therapeutic avenue. This review delves into the current state of salivary gland tissue engineering research, starting with a study of normal salivary
Externí odkaz:
https://doaj.org/article/20d47187d74442b3bf05333fae1ba504
Autor:
Luke A. Beardslee, Justin R. Halman, Andrea M. Unser, Yubing Xie, John Danias, Magnus Bergkvist, Susan T. Sharfstein, Karen Y. Torrejon
Publikováno v:
Bioengineering, Vol 10, Iss 6, p 679 (2023)
Glaucoma, where increased intraocular pressure (IOP) leads to damage to the optic nerve and loss of sight, is amongst the foremost causes of irreversible blindness worldwide. In primary open angle glaucoma, the increased IOP is a result of the malfun
Externí odkaz:
https://doaj.org/article/38449f1b15ad45ebbfdf69d459201dcb
Autor:
Hussain Dahodwala, Prashant Kaushik, Vijay Tejwani, Chih-Chung Kuo, Patrice Menard, Michael Henry, Bjorn G. Voldborg, Nathan E. Lewis, Paula Meleady, Susan T. Sharfstein
Publikováno v:
Current Research in Biotechnology, Vol 1, Iss , Pp 49-57 (2019)
Most therapeutic monoclonal antibodies in biopharmaceutical processes are produced in Chinese hamster ovary (CHO) cells. Technological advances have rendered the selection procedure for higher producers a robust protocol. However, information on mole
Externí odkaz:
https://doaj.org/article/effda2b4c08944dba65439c8d3ad4494
Autor:
Matthew Jorgensen, Pujhitha Ramesh, Miriam Toro, Emily Evans, Nicholas Moskwa, Xulang Zhang, Susan T. Sharfstein, Melinda Larsen, Yubing Xie
Publikováno v:
Bioengineering, Vol 9, Iss 1, p 38 (2022)
Understanding the different regulatory functions of epithelial and mesenchymal cell types in salivary gland development and cellular organization is essential for proper organoid formation and salivary gland tissue regeneration. Here, we demonstrate
Externí odkaz:
https://doaj.org/article/d2e6efc7c64c4826881ee6d2baed7ca4
Publikováno v:
Journal of Functional Biomaterials, Vol 6, Iss 3, Pp 963-985 (2015)
Among ocular pathologies, glaucoma is the second leading cause of progressive vision loss, expected to affect 80 million people worldwide by 2020. A primary cause of glaucoma appears to be damage to the conventional outflow tract. Conventional outflo
Externí odkaz:
https://doaj.org/article/c4a772fc1e1543cd8c13437b0b522d82
Publikováno v:
Antibodies, Vol 3, Iss 3, Pp 253-271 (2014)
Reduced culture temperature is an increasingly popular practice to improve recombinant protein yields in CHO cells. Recent studies have attributed the enhancement of protein titers at sub-physiological temperatures to increased mRNA levels as well as
Externí odkaz:
https://doaj.org/article/e1696363564f4c958a6874c313c28a01
Publikováno v:
Pharmaceuticals, Vol 9, Iss 3, p 38 (2016)
Heparin, the most widely used anticoagulant drug in the world today, remains an animal-derived product with the attendant risks of adulteration and contamination. A contamination crisis in 2007–2008 increased the impetus to provide non-animal-deriv
Externí odkaz:
https://doaj.org/article/bd448d38d8514310ac55af218dc16b9c
Autor:
Helen O. Masson, Mojtaba Samoudi, Caressa M. Robinson, Chih-Chung Kuo, Linus Weiss, Km Shams Ud Doha, Alex Campos, Vijay Tejwani, Hussain Dahodwala, Patrice Menard, Bjorn G. Voldborg, Susan T. Sharfstein, Nathan E. Lewis
Publikováno v:
bioRxiv
Understanding protein secretion has considerable importance in the biotechnology industry and important implications in a broad range of normal and pathological conditions including development, immunology, and tissue function. While great progress h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53676e5d6c116dc02cf3c9d17fd3b921
https://doi.org/10.1101/2023.05.04.539316
https://doi.org/10.1101/2023.05.04.539316
