Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Susan T Howard"'
Absence of the Genetic Marker IS6110 from a Strain of Mycobacterium tuberculosis Isolated in Ontario
Publikováno v:
Canadian Journal of Infectious Diseases, Vol 9, Iss 1, Pp 48-53 (1998)
A 35-year-old female patient from Waterloo, Ontario was diagnosed with pulmonary tuberculosis in June 1995. Records indicated that the patient had emigrated from Laos circa 1990. A culture grown from a bronchoalveolar lavage specimen was identified a
Externí odkaz:
https://doaj.org/article/21ecfe344ed8426db80973de770f61d8
Autor:
Sruthi Vasireddy, Anita Strong, Kevin A. Nash, Elena Iakhiaeva, Richard J. Wallace, Barbara A. Brown-Elliott, Terry Smith, Nicholas Parodi, Martha Gee, Ravikiran Vasireddy, Susan T. Howard
Publikováno v:
Journal of Clinical Microbiology. 53:1211-1215
The erm (41) gene confers inducible macrolide resistance in Mycobacterium abscessus subsp. abscessus , calling into question the usefulness of macrolides for treating M. abscessus subsp. abscessus infections. With an extended incubation (14 days), is
Autor:
Peipei Zhang, Susan T. Howard, Xisheng Wang, Buka Samten, Xiuhua Pang, Xiu Lan Chen, Guangxiang Cao
Publikováno v:
Microbiology. 161:477-489
The regulatory mechanisms that control the ESX-1 secretion system, a key player in the pathogenesis of Mycobacterium tuberculosis, have not been fully elucidated. However, factors that regulate the ESX-1 substrate EspA usually affect ESX-1 function.
Autor:
Linda Bridge, Steven McNulty, Susan T. Howard, Ravikiran Vasireddy, Richard J. Wallace, Barbara A. Brown-Elliott, Kristopher L. Newman
Publikováno v:
Microbiology. 159:2323-2332
Nearly half of US clinical isolates of the emerging pathogen Mycobacterium abscessus were reported to exhibit smeared DNA during PFGE. This DNA degradation (Dnd) phenotype results from DNA phosphorothioation, a sulfur modification found in other bact
Autor:
Xisheng Wang, Amy R. Tvinnereim, Guangxiang Cao, Susan T. Howard, Xiuhua Pang, Xiu Lan Chen, Buka Samten
Publikováno v:
Journal of Bacteriology. 195:66-75
The ESX-1 secretion system exports the immunomodulatory protein ESAT-6 and other proteins important in the pathogenesis of Mycobacterium tuberculosis . Components and substrates of ESX-1 are encoded at several loci, but the regulation of the encoding
Autor:
Elena Iakhiaeva, Richard J. Wallace, Susan T. Howard, Joseph O. Falkinham, Barbara A. Brown Elliott, Leah Lande, Myra D. Williams, Steven McNulty, Rebecca Kwait, Kristopher L. Newman, Christine Turenne, Ravikiran Vasireddy
“ Mycobacterium avium subsp. hominissuis ” is an important cause of pulmonary disease. It is acquired from environmental sources, but there is no methodology for large population studies. We evaluated the potential of variable-number tandem-repea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87a9ff0ea6df89aa3fd933003083604f
https://europepmc.org/articles/PMC4809946/
https://europepmc.org/articles/PMC4809946/
Autor:
Guangxiang Cao, Xiuhua Pang, Shelley E. Haydel, Guihua Hou, Pierre F. Neuenschwander, Susan T. Howard
Publikováno v:
Tuberculosis. 91:S142-S149
The β-propeller gene Rv1057 of Mycobacterium tuberculosis is activated by envelope stress and was first characterized as a regulatory target of the TrcRS two-component system (TCS). Rv1057 expression is repressed by TrcRS, and the Rv1057 proximal pr
Autor:
Xiuhua Pang, Susan T. Howard
Publikováno v:
Journal of Bacteriology. 189:6213-6221
Coordinated regulation of molecular chaperones is an important feature of the bacterial stress response. The small molecular chaperone gene acr2 of Mycobacterium tuberculosis is activated by exposure to several stresses, including heat and the deterg
Autor:
Susan T. Howard, Anny Alsup, Roberto Kolter, Judith Recht, Xiuhua Pang, C. Rick Lyons, Thomas F. Byrd, Elizabeth Rhoades
Publikováno v:
Microbiology. 152:1581-1590
Mycobacterium abscessusis an increasingly important cause of human disease; however, virulence determinants are largely uncharacterized. Previously, it was demonstrated that a rough, wild-type human clinical isolate (390R) causes persistent, invasive
Autor:
Peter F. Barnes, Ramakrishna Vankayalapati, David L. Lakey, Homayoun Shams, Susan T. Howard, Buka Samten, Hassan Safi
Publikováno v:
Molecular Microbiology. 52:999-1012
Summary The mobile insertion sequence, IS 6110 , is an impor- tant marker in tracking of Mycobacterium tuberculosis strains. Here, we demonstrate that IS 6110 can upreg- ulate downstream genes through an outward-directed promoter in its 3¢¢¢ ¢ en