Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Susan Slovin"'
Autor:
Xiuyan Wang, Oriana Borquez-Ojeda, Jolanta Stefanski, Fang Du, Jinrong Qu, Jagrutiben Chaudhari, Keyur Thummar, Mingzhu Zhu, Ling-bo Shen, Melanie Hall, Paridhi Gautam, Yongzeng Wang, Brigitte Sénéchal, Devanjan Sikder, Prasad S. Adusumilli, Renier J. Brentjens, Kevin Curran, Mark B. Geyer, Sham Mailankhody, Roisin O’Cearbhaill, Jae H. Park, Craig Sauter, Susan Slovin, Eric L. Smith, Isabelle Rivière
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 22, Iss , Pp 377-387 (2021)
With the US Food and Drug Administration (FDA) approval of four CD19- and one BCMA-targeted chimeric antigen receptor (CAR) therapy for B cell malignancies, CAR T cell therapy has finally reached the status of a medicinal product. The successful manu
Externí odkaz:
https://doaj.org/article/ac2a507ac1554df1b9bab28f312a4318
Autor:
Mayu O Frank, Julia Kaufman, Suyan Tian, Mayte Suárez-Fariñas, Salina Parveen, Nathalie E Blachère, Michael J Morris, Susan Slovin, Howard I Scher, Matthew L Albert, Robert B Darnell
Publikováno v:
PLoS ONE, Vol 5, Iss 9 (2010)
Studies of patients with paraneoplastic neurologic disorders (PND) have revealed that apoptotic tumor serves as a potential potent trigger for the initiation of naturally occurring tumor immunity. The purpose of this study was to assess the feasibili
Externí odkaz:
https://doaj.org/article/d7942a27ce94402080ffa311eb0cf0ac
Autor:
Sacha Gnjatic, Lloyd J. Old, Gerd Ritter, Elke Jäger, Jonathan Melamed, James P. Allison, Caroline Savage, Victor E. Reuter, Sumit K. Subudhi, Susan Slovin, Peter T. Scardino, Howard Scher, Brett Carver, Yuichi Obata, Toshiaki Ishida, Eiichi Nakayama, Erika Ritter, Megan Holz, Denise Frosina, Achim A. Jungbluth, Bernardo Sgarbi Reis
PDF file 79K, GAG-HERV-K ch22q11.23 features. Endogenous retrovirus K from chromosome 22 is located on the q11.23 region, nearby the BCR, ZDHHC8P, IGLL1 and RGL4 genes. HERV-K ch22q11.23 has GAG-PRO, POL and ENV genes flanked by LTR sequences. The GA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0838c6564fc154b416058d804e0969b3
https://doi.org/10.1158/1078-0432.22452512
https://doi.org/10.1158/1078-0432.22452512
Autor:
Johann de Bono, Paul Workman, Aram Oganesian, Harold Keer, Chihche Lin, Ruth Riisnaes, Penelope Flohr, Mateus Crespo, Roberta Ferraldeschi, Joel Picus, Jorge Garcia, Fred Saad, Syed Hussain, Susan Slovin
Supplementary Data from Pharmacodynamic and Clinical Results from a Phase I/II Study of the HSP90 Inhibitor Onalespib in Combination with Abiraterone Acetate in Prostate Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9277d355e04d8d0cecd899a9da95eec8
https://doi.org/10.1158/1078-0432.22470513.v1
https://doi.org/10.1158/1078-0432.22470513.v1
Autor:
Johann de Bono, Paul Workman, Aram Oganesian, Harold Keer, Chihche Lin, Ruth Riisnaes, Penelope Flohr, Mateus Crespo, Roberta Ferraldeschi, Joel Picus, Jorge Garcia, Fred Saad, Syed Hussain, Susan Slovin
Purpose:Onalespib is a potent, fragment-derived second-generation HSP90 inhibitor with preclinical activity in castration-resistant prostate cancer (CPRC) models. This phase I/II trial evaluated onalespib in combination with abiraterone acetate (AA)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fc0717438788a30e083724b9d2bf80f
https://doi.org/10.1158/1078-0432.c.6527595.v1
https://doi.org/10.1158/1078-0432.c.6527595.v1
Autor:
Sacha Gnjatic, Lloyd J. Old, Gerd Ritter, Elke Jäger, Jonathan Melamed, James P. Allison, Caroline Savage, Victor E. Reuter, Sumit K. Subudhi, Susan Slovin, Peter T. Scardino, Howard Scher, Brett Carver, Yuichi Obata, Toshiaki Ishida, Eiichi Nakayama, Erika Ritter, Megan Holz, Denise Frosina, Achim A. Jungbluth, Bernardo Sgarbi Reis
PDF file 204K, Alignment of GAG proteins derived from human endogenous retroviruses and respective epitopes recognized by prostate cancer patient sera. A, Detail alignment from several GAG-HERV-K family members and the TI-35 binding site (red) highli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d83187d4b2f5169f2f987e5cdacca9a
https://doi.org/10.1158/1078-0432.22452503.v1
https://doi.org/10.1158/1078-0432.22452503.v1
Autor:
Sacha Gnjatic, Lloyd J. Old, Gerd Ritter, Elke Jäger, Jonathan Melamed, James P. Allison, Caroline Savage, Victor E. Reuter, Sumit K. Subudhi, Susan Slovin, Peter T. Scardino, Howard Scher, Brett Carver, Yuichi Obata, Toshiaki Ishida, Eiichi Nakayama, Erika Ritter, Megan Holz, Denise Frosina, Achim A. Jungbluth, Bernardo Sgarbi Reis
PDF file 90K, Supplementary Figure Legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16dc65e1ac690c49124931e31ae4c177
https://doi.org/10.1158/1078-0432.22452491
https://doi.org/10.1158/1078-0432.22452491
Autor:
Sacha Gnjatic, Lloyd J. Old, Gerd Ritter, Elke Jäger, Jonathan Melamed, James P. Allison, Caroline Savage, Victor E. Reuter, Sumit K. Subudhi, Susan Slovin, Peter T. Scardino, Howard Scher, Brett Carver, Yuichi Obata, Toshiaki Ishida, Eiichi Nakayama, Erika Ritter, Megan Holz, Denise Frosina, Achim A. Jungbluth, Bernardo Sgarbi Reis
Purpose: Human endogenous retroviruses (HERV) encode 8% of the human genome. While HERVs may play a role in autoimmune and neoplastic disease, no mechanistic association has yet been established. We studied the expression and immunogenicity of a HERV
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b21101ce75d0e9fd15608c515e17dc91
https://doi.org/10.1158/1078-0432.c.6522497.v1
https://doi.org/10.1158/1078-0432.c.6522497.v1
Autor:
Sacha Gnjatic, Lloyd J. Old, Gerd Ritter, Elke Jäger, Jonathan Melamed, James P. Allison, Caroline Savage, Victor E. Reuter, Sumit K. Subudhi, Susan Slovin, Peter T. Scardino, Howard Scher, Brett Carver, Yuichi Obata, Toshiaki Ishida, Eiichi Nakayama, Erika Ritter, Megan Holz, Denise Frosina, Achim A. Jungbluth, Bernardo Sgarbi Reis
PDF file 63K, Correlation between antibodies against GAG-HERV-K and group risk or Gleason score in cancer patients. Prostate cancer patients were split (A) in 3 groups according to Gleason score and classified from group risk 1 to 3 and compared to h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07daad0d6e03029ecd33457dc358bab6
https://doi.org/10.1158/1078-0432.22452497
https://doi.org/10.1158/1078-0432.22452497
Autor:
Sacha Gnjatic, Lloyd J. Old, Gerd Ritter, Elke Jäger, Jonathan Melamed, James P. Allison, Caroline Savage, Victor E. Reuter, Sumit K. Subudhi, Susan Slovin, Peter T. Scardino, Howard Scher, Brett Carver, Yuichi Obata, Toshiaki Ishida, Eiichi Nakayama, Erika Ritter, Megan Holz, Denise Frosina, Achim A. Jungbluth, Bernardo Sgarbi Reis
PDF file 341K, qPCR gene expression analysis of chromosome 22q11.23 region in cancer tissues. Total RNA from cancer tissues was submitted to DNAse treatment and reverse transcriptase reaction for cDNA synthesis. The resulting cDNA was used on qPCR to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d74f62af6328b84aaf835500ca2e24c9
https://doi.org/10.1158/1078-0432.22452509
https://doi.org/10.1158/1078-0432.22452509