Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Susan Skelly"'
Autor:
Keith B. Elkon, Susan Skelly, Andrew P. Parnassa, Wim J. Möller, Herbert Weissbach, Nathan Brot, Waleed Danho
Publikováno v:
Proceedings of the National Academy of Sciences. 83:7419-7423
The characteristics of eukaryotic ribosomal proteins P0, P1, and P2 (P proteins) and their antigenic determinants were studied using the sera of patients with systemic lupus erythematosus (SLE). P0, P1, and P2 were isolated as a macromolecular comple
Publikováno v:
BioEssays. 7:258-261
Autoantibodies to three eukaryotic 60S ribosomal phosphoproteins P0, P1 and P2 have been found in the sera of 10–20% of patients with systemic lupus erythematosus (SLE). These three proteins share a common epitope contained within the carboxy termi
Autor:
Herbert Weissbach, Nathan Brot, Susan Skelly, Thomas Watson, Dennis W. Stagey, Keith B. Elkon
Publikováno v:
Archives of Biochemistry and Biophysics. 267:398-403
Autoantibodies found in approximately 15% of patients with systemic lupus erythematosus recognize three 60 S ribosomal phosphoproteins P0, P1, and P2. Fab fragments obtained from sera of these patients inhibited globin mRNA translation in an in vitro
Autor:
Susan Skelly, Betty Redfield, Chee-Fook Fu, Herbert Weissbach, Barbara Dalie, Nathan Brot, Timothy A. Coleman
Publikováno v:
Proceedings of the National Academy of Sciences. 85:5497-5501
A polyclonal antibody to sigma 32, the heat shock sigma factor, has been used to show the presence of low levels of sigma 32 in Escherichia coli RNA polymerase preparations (E sigma 70), which explains the observed in vitro activity of E sigma 70 tow
Publikováno v:
Proceedings of the National Academy of Sciences. 84:8365-8369
S-30 extracts from Escherichia coli cells were used to express heat shock (HS) and non-HS genes in vitro in a DNA-directed protein synthesis system. The S-30 extracts prepared from cells that have been shifted to 45 degrees C express HS genes in vitr
Autor:
Nathan Brot, Steven J. Golombek, Herbert Weissbach, Keith B. Elkon, Susan Skelly, Lee D. Kaufman, Eloisa Bonfa
Publikováno v:
The New England journal of medicine. 317(5)
In 18 of 20 patients with psychosis secondary to systemic lupus erythematosus (SLE), autoantibodies to ribosomal P proteins were detected by immunoblotting and measured with a new radioimmunoassay using a synthetic peptide as antigen. The frequency o