Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Susan Simmons-Alling"'
Autor:
Wade H. Berrettini, Elliot S. Gershon, John I. Nurnberger, Joel Hamovit, Carolyn York, Juliet J. Guroff, Susan Simmons-Alling, Diane Kazuba, Adelaide S. Robb, Lynn R. Goldin, Anne L. Smith, M. Elizabeth Maxwell, Henry Choi, Maria Martinez, David Muniec
Publikováno v:
Psychiatric Genetics. 2:125-160
Twenty-one multiplex bipolar (BP) families, suitable for linkage studies, are described. The families include 365 informative persons (whose genotypes can be determined from available DNA samples), 154 of whom have BP, schizoaffective or recurrent un
Autor:
Susan Simmons-Alling
Publikováno v:
Archives of psychiatric nursing. 4(1)
This article reviews the current outcomes of twin, adoption, and family epidemiological studies. Psychlatric genetics research has made a major paradigm shift from epidemiology studies to molecular genetic research. The manner in which affective diso
Publikováno v:
Psychiatry research. 31(1)
The serotonin precursor tryptophan was used to test neuroendocrine responses in remitted bipolar patients and controls. Tryptophan was administered in the afternoon when spontaneous cortisol secretion is lower than in the morning. Following pilot stu
Autor:
Susan Simmons-Alling, Elliot S. Gershon, John I. Nurnberger, E.Kathyrn Worthington, Wade H. Berrettini
Publikováno v:
Psychiatry Research. 7:83-86
Determinations of the affinity constants (KD) and number of binding sites (Bmax) for platelet vasopressin receptors were done in euthymic bipolar patients and normal volunteers. No significant differences were found between these groups. In addition,
Autor:
Wade H. Berrettini, John I. Nurnberger, Markku Linnoila, Timo Seppälä, Mika Scheinin, Susan Simmons-Alling, William Narrow, Elliot S. Gershon
Publikováno v:
Biological Psychiatry. 20:257-269
In a search for trait markers in manic-depressive illness, we studied cerebrospinal fluid (CSF) and plasma monoamines and their metabolites in 25 lithium-treated euthymic bipolar patients (12 of whom provided unmedicated samples) and 30 normal volunt
Autor:
Peter Hotvedt, Wade H. Berrettini, Susan Simmons-Alling, Elliot S. Gershon, John I. Nurnberger
Publikováno v:
Journal of Affective Disorders. 8:55-59
In an attempt to evaluate the role of VIP in affective disorder, measurements of lymphocyte VIP receptors, and plasma and CSF VIP levels were made in unmedicated and lithium-treated euthymic bipolars and controls. Lithium decreased plasma (P=0.01) an
Autor:
John I. Nurnberger, N. Suzan Nadi, Carol A. Tamminga, David S. Goldstein, Eric Hollander, Judith L. Schreiber, Elliot S. Gershon, Linda Kessler, Suzanne S. Jimerson, Susan Simmons-Alling
Publikováno v:
Psychopharmacology. 84:200-204
The neurochemical specificity of physiological, biochemical, and psychological responses to dextroamphetamine was tested by pretreating volunteers with haloperidol (0.014 mg/kg IM), propranolol (0.1 mg/kg IV), thymoxamine (0.1 mg/kg IV), or placebo p
Autor:
Susan Simmons-Alling, C. Wesley Dingman, Lynn E. DeLisi, John I. Nurnberger, Lynn R. Goldin, Joel Hamovit
Publikováno v:
Biological psychiatry. 22(2)
Autor:
Dawn Lawrence, John I. Nurnberger, Natraj Sitaram, Susan Simmons-Alling, Carol A. Tamminga, Elliot S. Gershon, J. Christian Gillin, N. Suzan Nadi, David C. Jimerson
Publikováno v:
Psychiatry research. 9(3)
Cholinergic supersensitivity has been postulated to be an etiologic factor in affective disorder. After several pilot dose-response studies, we administered 8 mg of the cholinergic agonist arecoline subcutaneously to eight pairs of normal volunteer i
Autor:
Susan Simmons-Alling, John I. Nurnberger, Wade H. Berrettini, Juliet J. Guroff, Elliot S. Gershon
Publikováno v:
Psychiatry research. 19(2)
Seven persons (three normal volunteers and four euthymic bipolar patients) received one to four doses of gamma-aminobutyric acid (GABA) intravenously. All subjects reported dysphoria, and their mood disturbance scores on the Profile of Mood States we