Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Susan Sartorius-Mergenthaler"'
Autor:
Nilofer S. Azad, Susan Sartorius-Mergenthaler, Michelle A. Rudek, Anup Sharma, Nita Ahuja, Jennifer N. Durham, Stephanie Gaillard, Marianna Zahurak, Kim A. Reiss, Nicole M. Anders, Melinda Downs
Publikováno v:
Cancer.
BACKGROUND Epigenetic abnormalities are manifold in all solid tumors and include changes in chromatin configuration and DNA methylation. The authors designed a phase 1 study to evaluate the oral DNA methyltransferase inhibitor CC-486 combined with th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::38f2e031218ef224ab967dbad8f5a4ac
https://doi.org/10.1002/cncr.32138
https://doi.org/10.1002/cncr.32138
Autor:
Chimela Ohaji, Susan Sartorius-Mergenthaler, Vivek Subbiah, Ralph Zinner, Mark Yarchoan, Rachna T. Shroff, Rose Parkinson, Denise Gallagher, Nilofer S. Azad, Ashley O'Connor, Marianna Zahurak, Gary L. Rosner
Publikováno v:
British Journal of Cancer
Background: Cholangiocarcinoma is an aggressive malignancy with limited therapeutic options. MEK inhibition and antiangiogenic therapies have individually shown modest activity in advanced cholangiocarcinoma, whereas dual inhibition of these pathways
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b37d5b55f8d4ce59d18390d81148943
https://doi.org/10.1038/bjc.2017.418
https://doi.org/10.1038/bjc.2017.418
Autor:
Brandon Luber, Theresa S. Pritchard, Shuming Chen, Irwin Freed, Tracee L. McMiller, Janice Davis Sproul, Susan Sartorius-Mergenthaler, Hao Wang, Sowmya Ravi, Drew M. Pardoll, Evan J. Lipson, Suzanne L. Topalian, William H. Sharfman, Janis M. Taube, January T. Salas
Publikováno v:
Journal of Translational Medicine
Background Limited adjuvant treatment options exist for patients with high-risk surgically resected melanoma. This first-in-human study investigated the safety, tolerability and immunologic correlates of Melanoma GVAX, a lethally irradiated granulocy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7aa0c25ea66db4a522ce4bc9b4f06613
https://doi.org/10.1186/s12967-015-0572-3
https://doi.org/10.1186/s12967-015-0572-3
Autor:
Susan Sartorius-Mergenthaler, Nilofer S. Azad, Stephen B. Baylin, David Cosgrove, Kim A. Reiss, Stephanie Gaillard, Melinda Downs, Nita Ahuja, Michelle A. Rudek
Publikováno v:
Journal of Clinical Oncology. 33:TPS2619-TPS2619
TPS2619 Background: Epigenetic alterations leading to silencing of tumor-suppressor genes play a key role in carcinogenesis and are reversible, therefore representing an appealing anti-cancer targe...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::48b49ebe144f6c33fca343b7350916f0
https://doi.org/10.1200/jco.2015.33.15_suppl.tps2619
https://doi.org/10.1200/jco.2015.33.15_suppl.tps2619
Autor:
Ashley O'Connor, Chimela Ohaji, Nilofer S. Azad, Marianna Zahurak, Susan Sartorius-Mergenthaler, Rachna T. Shroff, Denise Gallagher, Gary L. Rosner, Ralph Zinner
Publikováno v:
Journal of Clinical Oncology. 33:4072-4072
4072 Background: CC is an aggressive disease with a dismal prognosis and no clear therapy in the refractory setting. Mek inhibition and anti-angiogenic therapies have shown modest activity in advan...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::51c14fcb98791a53070738691443103a
https://doi.org/10.1200/jco.2015.33.15_suppl.4072
https://doi.org/10.1200/jco.2015.33.15_suppl.4072