Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Susan S. Yamada"'
Autor:
Haiyun Xu, Ting Yang, T.N. Snider, Brian L. Foster, Susan S. Yamada, Kenn Holmbeck, H.F. Wimer
Membrane-type matrix metalloproteinase 1 (MT1-MMP) is a transmembrane zinc-endopeptidase that breaks down extracellular matrix components, including several collagens, during tissue development and physiological remodeling. MT1-MMP-deficient mice (MT
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f4635f0e036e37e887165fdbef09741
https://europepmc.org/articles/PMC4875876/
https://europepmc.org/articles/PMC4875876/
Autor:
Niels Behrendt, Julie Gavard, Kenn Holmbeck, Susan S. Yamada, Lars H. Engelholm, J. Silvio Gutkind, Thomas H. Bugge, Rebecca A. Wagenaar-Miller
Publikováno v:
Molecular and Cellular Biology. 27:6309-6322
Collagen degradation is essential for cell migration, proliferation, and differentiation. Two key turnover pathways have been described for collagen: intracellular cathepsin-mediated degradation and pericellular collagenase-mediated degradation. Howe
Autor:
Niels Behrendt, Thomas H. Bugge, Kenn Holmbeck, Susan S. Yamada, Alfredo A. Molinolo, Lars H. Engelholm, Leif R. Lund, Alejandro Carlos Curino, Boye Schnack Nielsen
Publikováno v:
The Journal of Cell Biology
We recently reported that uPARAP/Endo180 can mediate the cellular uptake and lysosomal degradation of collagen by cultured fibroblasts. Here, we show that uPARAP/Endo180 has a key role in the degradation of collagen during mammary carcinoma progressi
Publikováno v:
Journal of Cellular Physiology. 205:123-132
Both mammary gland development and mammary carcinogenesis involve extensive remodeling of the mammary gland extracellular matrix. The expression of four membrane-type matrix metalloproteinases (MT-MMPs) with matrix remodeling potential in development
Autor:
Andrius Masedunskas, Niels Behrendt, Daniel Leonard, Kenn Holmbeck, David A. Brenner, Arul Selvaraj, Daniel H. Madsen, Lars H. Engelholm, Sven Burgdorf, Thomas H. Bugge, Susan S. Yamada, Panomwat Amornphimoltham, Roberto Weigert, Henrik J. Jürgensen, Amanda Moyer, Diane E. Peters
Publikováno v:
The Journal of cell biology, vol 202, iss 6
The Journal of Cell Biology
The Journal of Cell Biology
Mannose receptor–mediated uptake of collagen by M2-like macrophages is a major mechanism of collagen turnover in mice.
Tissue remodeling processes critically depend on the timely removal and remodeling of preexisting collagen scaffolds. Nevert
Tissue remodeling processes critically depend on the timely removal and remodeling of preexisting collagen scaffolds. Nevert
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b2082eef9cface792f7ab67eb3b3760
https://escholarship.org/uc/item/4519p4j5
https://escholarship.org/uc/item/4519p4j5
Autor:
Stacie Kahan, William D. Swaim, Susan S. Yamada, Patricia M. Zerfas, Marek Sramko, Mee-Young Son, Joanne Shi, Ludmila Szabova, Kenn Holmbeck
Publikováno v:
Blood. 116(25)
The membrane-type matrix metalloproteinases (MT-MMPs) are essential for pericellular matrix remodeling in late stages of development, as well as in growth and tissue homeostasis in postnatal life. Although early morphogenesis is perceived to involve
Autor:
Susan S. Yamada, Kenn Holmbeck, Signe Ingvarsen, H.F. Wimer, Lars H. Engelholm, Niels Behrendt, Ludmila Szabova, Kaliopi Chrysovergis
Publikováno v:
Journal of Bone and Mineral Research
Journal of Bone and Mineral Research; Vol 24
Journal of Bone and Mineral Research; Vol 24
Skeletal formation is dependent on timely recruitment of skeletal stem cells and their ensuing synthesis and remodeling of the major fibrillar collagens, type I collagen and type II collagen, in bone and cartilage tissues during development and postn
Autor:
Susan S. Yamada
Publikováno v:
Current Protocols in Cell Biology
Cultured keratinocytes have been used by a number of investigators in studies investigating wound repair and carcinogenesis, and they have also proven useful as a model for differentiation. This unit describes a protocol for establishing human kerati
Autor:
Sarah Netzel-Arnett, Kali Chrysovergis, Susan S. Yamada, Kenn Holmbeck, Henning Birkedal-Hansen, Thomas H. Bugge, David J. Mitola
Publikováno v:
The Journal of biological chemistry. 277(47)
Matrix metalloproteinase-14 is required for degradation of fibrillar collagen by mesenchymal cells. Here we show that keratinocytes use an alternative plasminogen and matrix metalloproteinase-13-dependent pathway for dissolution of collagen fibrils.
Publikováno v:
The Journal of Cell Biology
The ability of single subunit chimeric receptors containing various integrin beta intracellular domains to mimic and/or inhibit endogenous integrin function was examined. Chimeric receptors consisting of the extracellular and transmembrane domains of