Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Susan S. Padalecki"'
Autor:
Julie A. Sterling, Gregory R. Mundy, Lynn M. Matrisian, Babatunde O. Oyajobi, Alyssa R. Merkel, Barry G. Grubbs, Susan S. Padalecki, Mai P. Nguyen, Rachelle W. Johnson
Supplementary Figure 1 from TGF-β Promotion of Gli2-Induced Expression of Parathyroid Hormone-Related Protein, an Important Osteolytic Factor in Bone Metastasis, Is Independent of Canonical Hedgehog Signaling
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f2aed51d09435bdf2338c70602d63f6
https://doi.org/10.1158/0008-5472.22391259.v1
https://doi.org/10.1158/0008-5472.22391259.v1
Autor:
Julie A. Sterling, Gregory R. Mundy, Lynn M. Matrisian, Babatunde O. Oyajobi, Alyssa R. Merkel, Barry G. Grubbs, Susan S. Padalecki, Mai P. Nguyen, Rachelle W. Johnson
Supplementary Figure Legends 1-2 from TGF-β Promotion of Gli2-Induced Expression of Parathyroid Hormone-Related Protein, an Important Osteolytic Factor in Bone Metastasis, Is Independent of Canonical Hedgehog Signaling
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3096a58fb4330f4481bab120c2453114
https://doi.org/10.1158/0008-5472.22391256.v1
https://doi.org/10.1158/0008-5472.22391256.v1
Autor:
Julie A. Sterling, Gregory R. Mundy, Lynn M. Matrisian, Babatunde O. Oyajobi, Alyssa R. Merkel, Barry G. Grubbs, Susan S. Padalecki, Mai P. Nguyen, Rachelle W. Johnson
Breast cancer frequently metastasizes to bone, in which tumor cells receive signals from the bone marrow microenvironment. One relevant factor is TGF-β, which upregulates expression of the Hedgehog (Hh) signaling molecule, Gli2, which in turn increa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6db509590ea2e6a8d50c7e66f3d56f59
https://doi.org/10.1158/0008-5472.c.6503202.v1
https://doi.org/10.1158/0008-5472.c.6503202.v1
Publikováno v:
JNCI Monographs. 2012:162-168
The diagnosis and detection of prostate cancer has undergone profound changes over the past three decades, due primarily to the development and widespread clinical use of prostate-specific antigen (PSA) testing. These changes have led to substantial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::926aae447efe2ab7b37145e3a5d06df2
https://doi.org/10.1093/jncimonographs/lgs038
https://doi.org/10.1093/jncimonographs/lgs038
Autor:
Arlan Richardson, Barry Grubbs, Asish R. Chaudhuri, Susan S. Padalecki, Eric de Waal, Yuji Ikeno, Brian Herman, Gregory R. Mundy, Beth Goins, Yingpei Zhang
Publikováno v:
Mechanisms of Ageing and Development. 128:213-221
Alteration of apoptotic activity has been observed in a number of tissues in aging mammals, but it remains unclear whether and/or how apoptosis may affect aging. Caspase-2 is a member of the cysteine protease family that plays a critical role in apop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f719655a45ca73362b3dd29ec0099dc
https://doi.org/10.1016/j.mad.2006.11.030
https://doi.org/10.1016/j.mad.2006.11.030
Autor:
Darren H. Wong, Eva Corey, Khalid S. Mohammad, Larry J. Suva, Susan S. Padalecki, Gregory A. Clines, John M. Chirgwin, Robert L. Vessella, Linda S. Higgins, Elizabeth G. Stebbins, Theresa A. Guise
Publikováno v:
Clinical Cancer Research. 12:6213s-6216s
Certain solid tumors metastasize to bone and cause osteolysis and abnormal new bone formation. The respective phenotypes of dysregulated bone destruction and bone formation represent two ends of a spectrum, and most patients will have evidence of bot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4290adfcd05ae056cd5d0870e8ce465e
https://doi.org/10.1158/1078-0432.ccr-06-1007
https://doi.org/10.1158/1078-0432.ccr-06-1007
Publikováno v:
Genes, Chromosomes and Cancer. 30:221-229
Microcell-mediated chromosome transfer allows for the introduction of normal chromosomes into tumor cells in an effort to identify putative tumor suppressor genes. We have used this approach to introduce an intact copy of chromosome 18 into the prost
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::673cf31e2d8f0a3fb2c35b076b55c090
https://doi.org/10.1002/1098-2264(2000)9999:9999<::aid-gcc1093>3.0.co
https://doi.org/10.1002/1098-2264(2000)9999:9999<::aid-gcc1093>3.0.co
Autor:
Marc F. Hansen, Dean A. Troyer, Tomo Saric, Robin J. Leach, Barbara G. Schneider, Susan S. Padalecki, Peter O'Connell
Publikováno v:
International Journal of Cancer. 85:654-658
Like most cancers, prostate cancer (CaP) is believed to be the result of the accumulation of genetic alterations within cells. Previous studies have implicated numerous chromosomal regions with elevated rates of allelic imbalance (AI), using mostly p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ad056a498029c269ef89493b97d201db
https://doi.org/10.1002/(sici)1097-0215(20000301)85:5<654::aid-ijc10>3.0.co
https://doi.org/10.1002/(sici)1097-0215(20000301)85:5<654::aid-ijc10>3.0.co
Autor:
Ken Williams, Tomo Saric, Leo Abadesco, Dean A. Troyer, Michael F. Sarosdy, Zoran Brkanac, Robin J. Leach, Susan S. Padalecki, Peter O'Connell
Publikováno v:
International Journal of Cancer. 81:219-224
Genetic alterations in primary prostate cancer (CaP) have been extensively studied, yet little is known about the genetic mechanisms underlying progression of primary CaP to metastatic prostate cancer. As a result, it is not possible to distinguish c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8dd35ab5092158b8432376f15f697c74
https://doi.org/10.1002/(sici)1097-0215(19990412)81:2<219::aid-ijc9>3.0.co
https://doi.org/10.1002/(sici)1097-0215(19990412)81:2<219::aid-ijc9>3.0.co
Autor:
Frederick R. Singer, Susan S. Padalecki, G. David Roodman, Maggie Nellissery, Zoran Brkanac, Marc F. Hansen, Robin J. Leach, K. Krishnan Unni
Publikováno v:
The American Journal of Human Genetics. 63:817-824
SummaryPaget disease of bone, or “osteitis deformans,” is a bone disorder characterized by rapid bone remodeling resulting in abnormal bone formation. It is the second most common metabolic bone disease after osteoporosis, affecting 3%–5% of su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3c669cfcf0b04b8ea69003f15cf2c13
https://doi.org/10.1086/302019
https://doi.org/10.1086/302019