Výsledky vyhledávání - "Susan R. Rittling"

Akademický článek

Restriction-modification mediated barriers to exogenous DNA uptake and incorporation employed by Prevotella intermedia.

Autor: Christopher D Johnston, Chelsey A Skeete, Alexey Fomenkov, Richard J Roberts, Susan R Rittling

Publikováno v: PLoS ONE, Vol 12, Iss 9, p e0185234 (2017)

Prevotella intermedia, a major periodontal pathogen, is increasingly implicated in human respiratory tract and cystic fibrosis lung infections. Nevertheless, the specific mechanisms employed by this pathogen remain only partially characterized and po

Externí odkaz: https://doaj.org/article/48fe3eb0c481446d85763e442d1bcb45

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Akademický článek

Early Cytokine Response to Infection with Pathogenic vs Non-Pathogenic Organisms in a Mouse Model of Endodontic Infection.

Autor: Aritsune Matsui, Danielle Stephens, Alpdogan Kantarci, Susan R Rittling

Publikováno v: PLoS ONE, Vol 10, Iss 7, p e0132752 (2015)

Using the subcutaneous chamber model of infection, we showed previously that a mixture of four endodontic pathogens (EP: P. intermedia, F. nucleatum, S. intermedius and P. micra) are able to persist without clearance for up to seven days, while a non

Externí odkaz: https://doaj.org/article/d1db9cb3558e4c36b2f6716169a90750

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Systematic evasion of the restriction-modification barrier in bacteria

Autor: Gary G. Borisy, Christopher D Johnston, Jacqueline R. Starr, Sean L. Cotton, Susan R. Rittling, Katherine P. Lemon, Floyd E. Dewhirst

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America

Significance Genetic engineering is a powerful approach for discovering fundamental aspects of bacterial physiology, metabolism, and pathogenesis as well as for harnessing the capabilities of bacteria for human use. However, the full power of genetic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9369730541b911bb563bc741b437662
http://europepmc.org/articles/PMC6561282

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SyngenicDNA: stealth-based evasion of restriction-modification barriers during bacterial genetic engineering

Autor: Gary G. Borisy, Christopher D Johnston, Sean L. Cotton, Jacqueline R. Starr, Floyd E. Dewhirst, Susan R. Rittling, Katherine P. Lemon

Restriction-modification (RM) systems hinder the use of genetic approaches in the vast majority of bacteria. Here, we describe a systematic approach to adapt genetic tools for use in bacteria that are genetically intractable or poorly tractable owing

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dba867e7ac20759b21bb056d6186184b

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Osteopontin binding to the alpha 4 integrin requires highest affinity integrin conformation, but is independent of post-translational modifications of osteopontin

Autor: Tommy Hui, Esben S. Sørensen, Susan R. Rittling

Publikováno v: Hui, T, Sørensen, E S & Rittling, S R 2015, ' Osteopontin binding to the alpha 4 integrin requires highest affinity integrin conformation, but is independent of post-translational modifications of osteopontin ', Matrix Biology, vol. 41, pp. 19-25 . https://doi.org/10.1016/j.matbio.2014.11.005

Osteopontin (OPN) is a ligand for the α4ß1 integrin, but the physiological importance of this binding is not well understood. Here, we have assessed the effect of post-translational modifications on OPN binding to the α4 integrin on cultured human

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67b92e333efdbafc457db70b8d697faf
https://doi.org/10.1016/j.matbio.2014.11.005

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DC-STAMP Is an Osteoclast Fusogen Engaged in Periodontal Bone Resorption

Autor: Mariane Maffei Azuma, Martin A. Taubman, Y Mazda, Marcelo Freire, C. Y. Wang, Takenobu Ishii, Alexandru Movila, Xiaozhe Han, Mikihito Kajiya, Wichaya Wisitrasameewong, Shinji Matsuda, Toshihisa Kawai, Maiko Suzuki, Susan R. Rittling, Kenji Egashira, M R Torruella, Hajime Sasaki

Publikováno v: Scopus
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP

Made available in DSpace on 2022-04-29T08:03:58Z (GMT). No. of bitstreams: 0 Previous issue date: 2017-06-01 Dendritic cell-specific transmembrane protein (DC-STAMP) plays a key role in the induction of osteoclast (OC) cell fusion, as well as DC-medi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0149bfcc66990f6ee20dc6fee7344a16
https://europepmc.org/articles/PMC5444615/

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Hindlimb-unloading suppresses B cell population in the bone marrow and peripheral circulation associated with OPN expression in circulating blood cells

Autor: Yoichi Ezura, Masashi Nagao, David T. Denhardt, Masaki Noda, Susan R. Rittling, Junji Nagata, Tadayoshi Hayata, Hiroaki Hemmi

Publikováno v: Journal of Bone and Mineral Metabolism. 33:48-54

Rodent hindlimb unloading (HU) by tail-suspension is a model to investigate disuse-induced bone loss in vivo. Previously, we have shown that osteopontin (OPN, also known as Spp1) is required for unloading-induced bone loss. However, how unloading aff

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a1da5995088f7e617b5eb92d6c46baf
https://doi.org/10.1007/s00774-014-0568-8

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Modulation of infection-mediated migration of neutrophils and CXCR2 trafficking by osteopontin

Autor: Aritsune Matsui, Christopher D Johnston, Tommy Hui, Montserrat Ruiz-Torruella, Susan R. Rittling, Ziyad Allahem, Rani Singh

Publikováno v: Immunology. 150(1)

Osteopontin (OPN) is a pro-inflammatory protein that paradoxically protects against inflammation and bone destruction in a mouse model of endodontic infection. Here we have tested the hypothesis that this effect of OPN is mediated by effects on migra

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc4ab7a7dde1f3277d20168a4679dd25
https://pubmed.ncbi.nlm.nih.gov/27599164

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Sympathetic control of bone mass regulated by osteopontin

Autor: Takuya Notomi, Masashi Nagao, Yoshitomo Saita, Shu Takeda, Timothy N. Feinstein, Hisashi Kurosawa, Jean-Pierre Vilardaga, David T. Denhardt, Tadayoshi Hayata, Yoichi Ezura, Masaki Noda, Kathryn X. Wang, Yayoi Izu, Hiroaki Hemmi, Gerard Karsenty, Susan R. Rittling, Ryo Hanyu, Tetsuya Nakamoto, Kazuo Kaneko

Publikováno v: Proceedings of the National Academy of Sciences. 108:17767-17772

The sympathetic nervous system suppresses bone mass by mechanisms that remain incompletely elucidated. Using cell-based and murine genetics approaches, we show that this activity of the sympathetic nervous system requires osteopontin (OPN), a cytokin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5cd27c9531f4e6978b2e9e718ca84b57
https://doi.org/10.1073/pnas.1109402108

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