Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Susan R. Pfeffer"'
Publikováno v:
Pharmaceuticals, Vol 8, Iss 4, Pp 836-847 (2015)
The interferon (IFN) family of cytokines not only has antiviral properties at various steps in the viral replication cycle, but also anticancer activity through multiple pathways that include inhibiting cell proliferation, regulating cellular respons
Externí odkaz:
https://doaj.org/article/700286deeb9849c0a8ada8e2adcdd6e4
Autor:
Lawrence M Pfeffer, Kui Li, Jaquelyn F Fleckenstein, Tony N Marion, Joel Diament, Chuan He Yang, Susan R Pfeffer, Meiyun Fan, Elizabeth Handorf, Charles R Handorf
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e104202 (2014)
Infection with the hepatitis C virus (HCV) is a major cause of chronic liver diseases and hepatocellular carcinoma worldwide, and thus represents a significant public health problem. The type I interferon (IFN), IFNα, has been successful in treating
Externí odkaz:
https://doaj.org/article/863f31a63f774ff18820ba4b3641ffbd
Publikováno v:
Biochemical and Biophysical Research Communications. 490:739-745
Type I interferon (IFNα/β) induces antiviral and antiproliferative responses in cells through the induction of IFN-stimulated genes (ISGs). Although the roles of IFN-activated STAT1 and STAT2 in the IFN response are well described, the function of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cde2cebb4f395937c879b6cdf54719a7
https://doi.org/10.1016/j.bbrc.2017.06.111
https://doi.org/10.1016/j.bbrc.2017.06.111
Autor:
Pamela B. Cassidy, Levy Kopelovich, Chuan He Yang, Susan R. Pfeffer, Lawrence M. Pfeffer, Kenneth F. Grossmann, Sancy A. Leachman, Meiyun Fan
Publikováno v:
Journal of Clinical Medicine, Vol 4, Iss 12, Pp 2012-2027 (2015)
Journal of Clinical Medicine
Volume 4
Issue 12
Pages 2012-2027
Journal of Clinical Medicine; Volume 4; Issue 12; Pages: 2012-2027
Journal of Clinical Medicine
Volume 4
Issue 12
Pages 2012-2027
Journal of Clinical Medicine; Volume 4; Issue 12; Pages: 2012-2027
MicroRNAs (miRNAs) are a class of 22–25 nucleotide RNAs that control gene expression at the post-transcriptional level. MiRNAs have potential as cancer biomarkers. Melanoma is a highly aggressive form of skin cancer accounting for almost 4% of canc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db4712d78eb03bb269a7511f1f90dc46
http://www.mdpi.com/2077-0383/4/12/1957
http://www.mdpi.com/2077-0383/4/12/1957
Publikováno v:
Pharmaceuticals, Vol 8, Iss 4, Pp 836-847 (2015)
Pharmaceuticals
Pharmaceuticals
The interferon (IFN) family of cytokines not only has antiviral properties at various steps in the viral replication cycle, but also anticancer activity through multiple pathways that include inhibiting cell proliferation, regulating cellular respons
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cbae0f6d9fecc1cce214e668d3ff2df
http://www.mdpi.com/1424-8247/8/4/836
http://www.mdpi.com/1424-8247/8/4/836
Autor:
Wei Li, Shivaputra A. Patil, Souvik Banerjee, Lawrence M. Pfeffer, Dejian Ma, Susan R. Pfeffer, Jin Wang, Duane D. Miller
Publikováno v:
Molecules, Vol 20, Iss 9, Pp 17152-17165 (2015)
Molecules
Volume 20
Issue 9
Pages 17152-17165
Molecules
Volume 20
Issue 9
Pages 17152-17165
A novel series of 5H-chromenopyridines was identified as anticancer agents in our continuing effort to discover and develop new small molecule anti-proliferative agents. Based on our initial lead SP-6-27 compound, we designed and synthesized novel tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e9b4f23d60fd9532c6693d86743eb9b
http://www.mdpi.com/1420-3049/20/9/17152
http://www.mdpi.com/1420-3049/20/9/17152
Publikováno v:
Drug Development Research. 76:270-277
MicroRNAs (miRNAs) are small endogenous noncoding RNAs that suppress gene expression at the post-transcriptional level. In the past decade, miRNAs have been extensively studied in a number of different human cancers. MiRNAs have been identified to ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8538a4893ed3cb143f1cede89251595a
https://doi.org/10.1002/ddr.21257
https://doi.org/10.1002/ddr.21257
The Oncogenic MicroRNA-21 Inhibits the Tumor Suppressive Activity of FBXO11 to Promote Tumorigenesis
Autor:
Elena M. Paulus, Andrew M. Davidoff, Yinan Wang, Junming Yue, Chuan He Yang, Susan R. Pfeffer, Michelle Sims, Lawrence M. Pfeffer, Vijay Gandhi Linga
Publikováno v:
Journal of Biological Chemistry. 290:6037-6046
The microRNA miR-21 is overexpressed in most human cancers and accumulating evidence indicates that it functions as an oncogene. Since miRNAs suppress the expression of their target genes, we hypothesized that some miR-21 targets may act as tumor sup
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7268bd3be966dfc42b794be00eb29fe3
https://doi.org/10.1074/jbc.m114.632125
https://doi.org/10.1074/jbc.m114.632125
Autor:
Junming Yue, Ping He, Yinan Wang, Michelle Sims, Chun Cai, Susan R. Pfeffer, Chuan He Yang, Lawrence M. Pfeffer, Frederick A. Boop, Jinjun Cheng
Publikováno v:
Oncotarget
// Chuan He Yang 1,2 , Yinan Wang 1,2 , Michelle Sims 1,2 , Chun Cai 2,3 , Ping He 2,4 , Junming Yue 1,2 , Jinjun Cheng 1 , Frederick A. Boop 3 , Susan R. Pfeffer 1,2 and Lawrence M. Pfeffer 1,2 1 Department of Pathology and Laboratory Medicine, Univ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e40349a69569c1f51161f8409150080
https://pubmed.ncbi.nlm.nih.gov/27705947
https://pubmed.ncbi.nlm.nih.gov/27705947
Publikováno v:
Hepatology. 55:666-675
Chemokines and inflammatory cytokines are key regulators of immunity and inflammation during viral infections. Hepatitis C virus (HCV) is a hepatotropic RNA virus frequently associated with chronic liver inflammation and hepatocellular carcinoma. Int
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c75e0f39b138f46b18f5dc3fed30b1e2
https://doi.org/10.1002/hep.24763
https://doi.org/10.1002/hep.24763