Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Susan R. Meier-Davis"'
Autor:
Richard D. Hamlin, Betsy Huang, Jutaro Shudo, Fatima M. Arjmand, Kevin Dines, Susan R. Meier-Davis, Chad Christianson, Tetsuto Nagata, Jainye Wen
Publikováno v:
Cutaneous and Ocular Toxicology. 31:312-317
Transdermal patch administration results in a locally high concentration of drug that induce local toxicity, including tumorogenicity. As a worst-case scenario for consequences of repeated application on neoplastic growth, the melanin-binding drug, r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dde21b7d161c1d66e21b5f7a72308d37
https://doi.org/10.3109/15569527.2012.676119
https://doi.org/10.3109/15569527.2012.676119
Publikováno v:
Cutaneous and Ocular Toxicology. 31:20-25
The relationship between allergic contact dermatitis (ACD) and age has not been well documented. We searched for articles and textbooks based on age-ACD relationship and evaluated relevant data. The frequency of skin reactions to allergens increased
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc7351cdc0dccf418bde7005ddb20378
https://doi.org/10.3109/15569527.2011.595749
https://doi.org/10.3109/15569527.2011.595749
Publikováno v:
International journal of toxicology. 34(1)
Topical alprostadil cream (Vitaros) is approved in Canada and Europe for the treatment of erectile dysfunction. To determine the effects on the female urogenital tract with repeated administration of the entire dose (300 μg alprostadil containing 2.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::625873f4f291619879597e5b299be276
https://pubmed.ncbi.nlm.nih.gov/25691520
https://pubmed.ncbi.nlm.nih.gov/25691520
Autor:
Lisa M. Diehl, Min Meng, Jutaro Shudo, Susan R. Meier-Davis, Fatima M. Arjmand, Betsy Huang, Rebecca M. Lucke, Tetsuto Nagata, Weiwei Yuan, Jianye Wen
Publikováno v:
International journal of toxicology. 31(4)
Donepezil hydrochloride is a reversible acetyl cholinesterase inhibitor approved for Alzheimer disease treatment. As an alternate therapy, a donepezil hydrochloride transdermal patch is in development. Recommended nonclinical safety studies include a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::327b455b66d053f228f8ea16e7fba295
https://pubmed.ncbi.nlm.nih.gov/22705881
https://pubmed.ncbi.nlm.nih.gov/22705881
Publikováno v:
Journal of Pharmaceutics & Drug Delivery Research.
Enhancing the Skin Flux of Tolnaftate Utilizing the Novel Excipient, Dodecyl-2-N, NDimethylaminopropionate (DDAIP) Penetration of drug through the stratum corneum to reach the underlying epidermal and dermal layers is a critical step for effective th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d69a3c1613f2a1c366101c6fb5fbfa21
https://doi.org/10.4172/2325-9604.1000102
https://doi.org/10.4172/2325-9604.1000102
Autor:
C. Toole, Jianye Wen, B. Cayme, Tetsuto Nagata, Susan R. Meier-Davis, L. Dieh, Jutaro Shudo, R. Murgasova, F. M. Arjm
Publikováno v:
Journal of Drug Metabolism & Toxicology. 3
Donepezil hydrochloride is a centrally acting, reversible acetyl cholinesterase inhibitor approved for Alzheimer’s disease therapy. Donepezil is marketed as an oral tablet but a transdermal patch may have advantages as an alternate therapy. To dete
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b0d0aeaa5d9138db161756173c5862fe
https://doi.org/10.4172/2157-7609.1000129
https://doi.org/10.4172/2157-7609.1000129
Publikováno v:
Hair : Therapy & Transplantation.
Transdermal delivery of topically applied compounds is limited by the stratum corneum (SC) protective barrier. Penetration enhancers have been employed to perturb the skin barrier and enhance the transdermal flux of drugs. The novel excipient, dodecy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b93014a0ccbb758a7c8a70cd4779212d
https://doi.org/10.4172/2167-0951.1000105
https://doi.org/10.4172/2167-0951.1000105
Autor:
Masahiro Yamaji, Fatima M. Arjm, Susan R. Meier-Davis, Yoshiko Katori-Stowell, Tetsuto Nagata, Jianye Wen, Jutaro Shudo, Marie-Eve Rodrigue
Publikováno v:
Journal of Drug Metabolism & Toxicology. 3
Donepezil hydrochloride formulated in a transdermal patch for weekly administration is an alternative to the approved daily oral tablet. Transdermal delivery has a locally high concentration at the application site causing potential safety issues. To
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d5e057ff0f65998fd1c01d54d0931ef4
https://doi.org/10.4172/2157-7609.1000123
https://doi.org/10.4172/2157-7609.1000123
Publikováno v:
Cutaneous and ocular toxicology. 31(2)
Knowledge on age-relationship to irritant contact dermatitis (ICD) remains of interest. We searched for articles and textbooks on age-relationship to ICD and evaluated relevant data. Irritant response may be enhanced in children and decline with incr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42f0c5ce01775cd269393e34a3b79926
https://pubmed.ncbi.nlm.nih.gov/21967594
https://pubmed.ncbi.nlm.nih.gov/21967594
Publikováno v:
Cellular signalling. 4(5)
Many cells develop enhanced adenylate cyclase activity after prolonged exposure to drugs that acutely inhibit the enzyme and it has been suggested that this adaptation may be due to an increase in Gs alpha. We have treated wild-type and Gs alpha-defi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53769f896b406c113e7b3ec8962d8fbc
https://pubmed.ncbi.nlm.nih.gov/1329904
https://pubmed.ncbi.nlm.nih.gov/1329904