Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Susan R S, Gottesman"'
Autor:
Diane, Wang, Charlotte L, Marous, Fatih, Ozay, Alisa, Timashpolsky, Rahul D, Gulati, Susan R S, Gottesman, Marina, Boruk, Roman, Shinder, Nickisa M, Hodgson
Publikováno v:
Orbit. :1-5
Intravascular large B-cell lymphoma (IVLBCL) is a rare type of lymphoma, involving the lumen of predominantly small blood vessels, especially capillaries. The orbit is an uncommon site of involvement for IVLBCL, and diagnosis before autopsy is even m
Autor:
Anton V. Rets, Susan R. S. Gottesman
Publikováno v:
Case Reports in Pathology, Vol 2014 (2014)
Lymphomas with overlapping histological features of two distinct entities cause difficulty in classification. Their classification is of particular significance when the two alternatives require different treatment modalities. We present a diagnostic
Externí odkaz:
https://doaj.org/article/aea8cb027c6d4fda8586c4dff45093ff
Autor:
Irina Jilishitz, Scott Schoninger, Allison VanInwegen VanInwegen, Lingyue Yan, Jason Luis Quiñones, Stacy W. Blain, Grace Y. Chen, Jonathan Somma, Yun Wu, Jared Pasetsky, Vladislav Tsiperson, Manasi P. Jogalekar, Susan R. S. Gottesman, Priyank Patel
Publikováno v:
Molecular cancer research : MCR. 19(11)
Resistance to cyclin D-CDK4/6 inhibitors (CDK4/6i) represents an unmet clinical need and is frequently caused by compensatory CDK2 activity. Here we describe a novel strategy to prevent CDK4i resistance by using a therapeutic liposomal:peptide formul
Autor:
Grace Y. Chen, Jason Luis Quiñones, Irina Jilishitz, Jared Pavetsky, Susan R. S. Gottesman, Priyank Patel, Jonathan Somma, Lingyue Yan, Manasi P. Jogalekar, Vladislav Tsiperson, Scott Schoninger, Stacy W. Blain, Allison VanInwegen VanInwegen, Yun Wu
Publikováno v:
Cancer Research. 81:LB115-LB115
Resistance to cyclin D-cdk4/6 inhibitors (CDK4/6i) represents an unmet clinical need and is frequently caused by compensatory CDK2 activity. Here we describe a novel strategy to prevent CDK4i resistance by using a therapeutic liposomal:peptide formul
Autor:
Usha Govindarajulu, Jonathan Somma, Vladislav Tsiperson, Susan R. S. Gottesman, Priyank Patel, Lisa Dresner, Stacy W. Blain
Publikováno v:
Molecular cancer research : MCR. 17(3)
Cdk4-targeting drugs, such as palbociclib, are approved for metastatic ER/PR+, Her2− breast cancer. However, other than loss of retinoblastoma, which is very rare in this subset, there are no biomarkers to predict response. Cyclin D or cdk4 levels
Autor:
Ralf Wagner, Stacy W. Blain, Cindy Gomez, Angela L. Tyner, Priyank Patel, Benedikt Asbach, Susan R. S. Gottesman, Elina Shetyn
Publikováno v:
Cancer Research. 75:P5-08
The oncogenes Cyclin D and cdk4 are overexpressed in breast cancer, but the levels of these proteins are not always accurate indicators of oncogenic activity because p27Kip1 is required to assemble this otherwise unstable dimer. However, p27’s asso
Publikováno v:
Molecular cancer research : MCR. 16(3)
Cyclin-dependent kinase 4/6 (CDK4/6)-specific inhibitors, such as palbociclib, have shown clinical efficacy, but primary or secondary resistance has emerged as a problem. To develop more effective therapeutic approaches, investigation is needed into
Autor:
Jinjuan Yao, Albert S. Braverman, Constantine A. Axiotis, Susan R. S. Gottesman, Getinet Ayalew
Publikováno v:
American Journal of Surgical Pathology. 37:1407-1412
Adult T-cell leukemia/lymphoma (ATLL) is caused by the HTLV-1 virus, endemic to Japan and the Caribbean, and is likely derived from cells with the T-regulatory phenotype. The malignant cells express IL2 receptor α (CD25), and the majority express tr
Autor:
Hongjie Li, Susan R. S. Gottesman
Publikováno v:
American Journal of Clinical Pathology. 149:S84-S84
Autor:
Karen M. Samanich, Joanne Edington, Susan R. S. Gottesman, G. Jeanette Thorbecke, Christina D. Swenson, Donald V. Belsito
Publikováno v:
Annals of the New York Academy of Sciences. 774:249-258
IgD-receptors are associated with augmented antibody production in vivo and are induced on CD4+ T cells by aggregated IgD in young but not in aged mice. In the current study orally or intraperitoneally administered DHEAS was found to enhance antibody