Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Susan Potter Perigo"'
Publikováno v:
Journal of Lipid Research, Vol 42, Iss 5, Pp 824-833 (2001)
Arterial wall lipid retention is believed to be due primarily to ionic interactions between lipoproteins and proteoglycans. Thus, oxidized low density lipoproteins (LDL), with decreased positive charge relative to native LDL, should have decreased in
Externí odkaz:
https://doaj.org/article/da818668e9dd437ba5bee6b8a91fe80f
Publikováno v:
Matrix Biology. 42:74-92
The contribution of hyaluronan-dependent pericellular matrix to TGF-β1-driven induction and maintenance of myofibroblasts is not understood. Hyaluronan is an extracellular matrix (ECM) glycosaminoglycan important in cell adhesion, proliferation and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46b3d236775173829b072b31967dc9ff
https://doi.org/10.1016/j.matbio.2014.12.001
https://doi.org/10.1016/j.matbio.2014.12.001
Autor:
Stephen P. Evanko, Michael G. Kinsella, Susan Potter-Perigo, Mervyn J. Merrilees, Thomas N. Wight
Publikováno v:
Biochimica et Biophysica Acta (BBA) - General Subjects. 1840:2441-2451
Versican is an extracellular matrix (ECM) proteoglycan that is present in the pericellular environment of most tissues and increases in many different diseases. Versican interacts with cells to influence the ability of cells to proliferate, migrate,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::726ab85661da2410bd0ad622c1b2da53
https://doi.org/10.1016/j.bbagen.2013.12.028
https://doi.org/10.1016/j.bbagen.2013.12.028
Autor:
Marika Bogdani, Nadine Nagy, Anthony J. Day, Paul L. Bollyky, Thomas N. Wight, Susan Potter-Perigo, Pamela Y. Johnson
Publikováno v:
Diabetes
Hyaluronan (HA) is an extracellular matrix glycosaminoglycan that is present in pancreatic islets, but little is known about its involvement in the development of human type 1 diabetes (T1D). We have evaluated whether pancreatic islets and lymphoid t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74e969a6faf34931f8524cf9156fee4e
https://doi.org/10.2337/db13-1658
https://doi.org/10.2337/db13-1658
Autor:
Susan Potter Perigo, Christina K. Chan, Thomas N. Wight, Michael J. Peters, Michael G. Kinsella, Rebecca L. Hull
Publikováno v:
Journal of Biological Chemistry. 287:37154-37164
Islet amyloid, a pathologic feature of type 2 diabetes, contains the islet β-cell peptide islet amyloid polypeptide (IAPP) as its unique amyloidogenic component. Islet amyloid also contains heparan sulfate proteoglycans (HSPGs) that may contribute t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13899e7a139bf91d3ce0f682e557d5e8
https://doi.org/10.1074/jbc.m112.409847
https://doi.org/10.1074/jbc.m112.409847
Publikováno v:
Matrix Biology. 31:90-100
The ability of lymphocytes to migrate freely through connective tissues is vital to efficient immune function. How the extracellular matrix (ECM) may affect T cell adhesion and migration is not well understood. We have examined the adhesion and migra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90a694092dcef85ecff02ff4f024d212
https://doi.org/10.1016/j.matbio.2011.10.004
https://doi.org/10.1016/j.matbio.2011.10.004
Autor:
Leonard C. Altman, Thomas N. Wight, Kathleen R. Braun, Susan Potter-Perigo, Pamela Y. Johnson, Stephen P. Evanko, Christina K. Chan, Thomas S. Wilkinson
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 43:109-120
Viral infections are known to exacerbate asthma and other lung diseases in which chronic inflammatory processes are implicated, but the mechanism is not well understood. The viral mimetic, polyinosine-polycytidylic acid, causes accumulation of a vers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3861abfd2763068ab159f7f2c3394927
https://doi.org/10.1165/rcmb.2009-0081oc
https://doi.org/10.1165/rcmb.2009-0081oc
Autor:
Benjamin Van Biber, Christina K. Chan, Thomas N. Wight, Michael A. Laflamme, Susan Potter-Perigo, Charles E. Murry, Marsha W. Rolle, Kathleen R. Braun
Publikováno v:
Journal of Cellular Biochemistry. 111:585-596
Proteoglycans and hyaluronan play critical roles in heart development. In this study, human embryonic stem cells (hESC) were used as a model to quantify the synthesis of proteoglycans and hyaluronan in hESC in the early stages of differentiation, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::baa69ba00b6807401b62a6ce79128745
https://doi.org/10.1002/jcb.22744
https://doi.org/10.1002/jcb.22744
Autor:
Christina K. Chan, Brian Kinsella, Rebecca P. Wu, Stephen P. Evanko, Paul L. Bollyky, Thomas N. Wight, Brandon Teng, Helena Reijonen, Kathy R. Braun, John A. Gebe, Kelly Guebtner, Gerald T. Nepom, S. Alice Long, Susan Potter-Perigo
Publikováno v:
Cellular & Molecular Immunology. 7:211-220
Hyaluronan (HA) production by dendritic cells (DCs) is known to promote antigen presentation and to augment T-cell activation and proliferation. We hypothesized that pericellular HA can function as intercellular 'glue' directly mediating T cell-DC bi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3c9f5673bc1de9a4d66fcbcf6b70a3c
https://doi.org/10.1038/cmi.2010.9
https://doi.org/10.1038/cmi.2010.9
Autor:
Michael G. Kinsella, Mandy L. Ballinger, Peter J. Little, Luiz E.M. Cardoso, Thomas N. Wight, Susan Potter-Perigo, Kathleen R. Braun, Christina K. Chan, Karin E. Bornfeldt
Publikováno v:
Journal of Biological Chemistry. 285:6987-6995
The synthesis of proteoglycans involves steps that regulate both protein and glycosaminoglycan (GAG) synthesis, but it is unclear whether these two pathways are regulated by the same or different signaling pathways. We therefore investigated signalin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::444cf18068c83b24208fb1e65ad99ee5
https://doi.org/10.1074/jbc.m109.088674
https://doi.org/10.1074/jbc.m109.088674