Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Susan Pedigo"'
Publikováno v:
Metallomics. 11:475-482
Cadherins are the transmembrane component in adherens junctions, structures that link the actin cytoskeletons in adjacent cells within solid tissues including neurological synapses, epithelium and endothelium. Cell-cell adhesion by cadherins requires
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cfa87f55ebdf1e9f17e919d0e2fee75
https://doi.org/10.1039/c8mt00349a
https://doi.org/10.1039/c8mt00349a
Publikováno v:
Biomacromolecules. 21(6)
Recently, there has been growing interest in harnessing genetically engineered polymers to develop responsive biomaterials, such as hydrogels. Unlike their synthetic counterparts, genetically engineered polymers are produced without the use of toxic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::735bdc30d6d10bbf7e0114ce77f22eeb
https://pubmed.ncbi.nlm.nih.gov/32320226
https://pubmed.ncbi.nlm.nih.gov/32320226
Publikováno v:
Biochemistry. 57:6404-6415
Cadherins are calcium-dependent, transmembrane adhesion molecules that assemble through direct noncovalent association of their N-terminal extracellular modular domains. As the transmembrane component of adherens junctions, they indirectly link adher
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::961556300d70f09f2c6705961e7999c8
https://doi.org/10.1021/acs.biochem.8b00733
https://doi.org/10.1021/acs.biochem.8b00733
Publikováno v:
Biochemistry. 54:836-843
In spite of their structural similarities, epithelial (E-) and neural (N-) cadherin are expressed at different types of synapses and differ significantly in their dimerization kinetics. Recent studies proposed a transient intermediate in E-cadherin a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c01941de82a1b2cee3dfb08d9ee095e9
https://doi.org/10.1021/bi5010415
https://doi.org/10.1021/bi5010415
Autor:
Nagamani Vunnam, Susan Pedigo
Publikováno v:
Protein Science. 21:1006-1014
In spite of structural similarities Epithelial- (E-) and Neural- (N-) cadherins are expressed at two types of synapses and differ significantly in dimer disassembly kinetics. Recent studies suggested that the formation of an X-dimer intermediate in E
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9353e20b3b00225cea4aaf75792e231c
https://doi.org/10.1002/pro.2083
https://doi.org/10.1002/pro.2083
Autor:
Susan Pedigo, Nagamani Vunnam
Publikováno v:
Biochemistry. 50:8437-8444
Cadherins are cell adhesion proteins that are important for tissue formation and integrity. Cell-cell adhesion occurs through the formation of the strand-crossover dimer between identical cadherins on the surface of neighboring cells. The strand-cros
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0496644aa4e697a2abd986ec69667c5e
https://doi.org/10.1021/bi200902s
https://doi.org/10.1021/bi200902s
Autor:
Nagamani Vunnam, Susan Pedigo
Publikováno v:
Biochemistry. 50:2973-2982
Neural cadherin (N-cadherin) is a calcium-dependent homophilic cell-adhesive molecule and critical for synaptogenesis and synapse maintenance. The extracellular region plays an important role in cadherin-mediated cell adhesion and has five tandemly r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7603fe5aae267e8214fc5dc7f9966b16
https://doi.org/10.1021/bi101872b
https://doi.org/10.1021/bi101872b
Publikováno v:
Biochemistry. 50:2951-2961
Epithelial- and neural-cadherins are specifically localized at synapses in neurons which can change the shape and contact surface on a time scale of seconds to months. We have focused our studies on the role of the extracellular domains of cadherins
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbb3bf7982ba80f5055e4829ba62b109
https://doi.org/10.1021/bi2001246
https://doi.org/10.1021/bi2001246
Autor:
Nicole A. Housley, Huaying Zhao, John M. Rutherford, Susan Pedigo, Corey Nichols, Alka Prasad
Publikováno v:
Proteins: Structure, Function, and Bioinformatics. 62:111-121
Epithelial cadherin is a transmembrane protein that is essential in calcium-dependent cell–cell recognition and adhesion. It contains five independently folded globular domains in its extracellular region. Each domain has a seven-strand β-sheet im
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f7cc9337814f0bb81b734524585be3e
https://doi.org/10.1002/prot.20657
https://doi.org/10.1002/prot.20657
Publikováno v:
Biophysical Journal. 108(2)
Cadherins are transmembrane proteins responsible for calcium dependent cell-cell adhesion. Classical cadherins have a common structure with five extracellular domains, connected by a 7-residue sequence linker region. Cadherins mediate adhesion via Ad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a3a4f690631be63f9d821ec8e94052d