Zobrazeno 1 - 10
of 110
pro vyhledávání: '"Susan P. Whitman"'
Autor:
Jason H. Mendler, Kati Maharry, Heiko Becker, Ann-Kathrin Eisfeld, Leigha Senter, Krzysztof Mrózek, Jessica Kohlschmidt, Klaus H. Metzeler, Sebastian Schwind, Susan P. Whitman, Jihane Khalife, Michael A. Caligiuri, Rebecca B. Klisovic, Joseph O. Moore, Thomas H. Carter, Guido Marcucci, Clara D. Bloomfield
Publikováno v:
Haematologica, Vol 98, Iss 8 (2013)
Externí odkaz:
https://doaj.org/article/74884b369e1c4b6c99f3a0b79add6408
Autor:
Heiko Becker, Kati Maharry, Michael D. Radmacher, Krzysztof Mrózek, Klaus H. Metzeler, Susan P. Whitman, Sebastian Schwind, Jessica Kohlschmidt, Yue-Zhong Wu, Bayard L. Powell, Thomas H. Carter, Jonathan E. Kolitz, Meir Wetzler, Andrew J. Carroll, Maria R. Baer, Joseph O. Moore, Michael A. Caligiuri, Richard A. Larson, Guido Marcucci, Clara D. Bloomfield
Publikováno v:
Haematologica, Vol 96, Iss 10 (2011)
Background The alleles of the Wilms tumor 1 (WT1) polymorphism rs16754 harbor adenine (A) or guanine (G). Recently, rs16754 has been reported to affect the outcome of patients with cytogenetically normal acute myeloid leukemia. To validate this findi
Externí odkaz:
https://doaj.org/article/ac7ea9aa6249450a9fbb9e1ad063ac5f
Autor:
Kimberly F. Young, Rebeca Gardner, Victoria Sariana, Susan A. Whitman, Mitchell J. Bartlett, Torsten Falk, Helena W. Morrison
Publikováno v:
Journal of Neuroinflammation, Vol 18, Iss 1, Pp 1-15 (2021)
Abstract Background Ischemic stroke is an acquired brain injury with gender-dependent outcomes. A persistent obstacle in understanding the sex-specific neuroinflammatory contributions to ischemic brain injury is distinguishing between resident microg
Externí odkaz:
https://doaj.org/article/04da039e110146a680000c6ad0ea0b54
Autor:
Christoph Plass, Clara D. Bloomfield, Guido Marcucci, Michael Lübbert, Thomas D. Schmittgen, Susan P. Whitman, Katie Maharry, Nadya Blagitko-Dorfs, Shih-Shih Chen, Rainer Claus, Jinmai Jiang, Romulo M. Brena, Kristi L. Bennett, Björn Hackanson
Supplementary Table 1 from Epigenetic Modification of CCAAT/Enhancer Binding Protein α Expression in Acute Myeloid Leukemia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c2189670b6808706900e24f1313f436
https://doi.org/10.1158/0008-5472.22376091
https://doi.org/10.1158/0008-5472.22376091
Autor:
Alison Walker, Katherine Walsh, Clara D. Bloomfield, William Blum, James S. Blachly, Susan P. Whitman, Anjali Mishra, Gerard Lozanski, John C. Byrd, Sumithira Vasu, Rebecca B. Klisovic, Michael A. Caligiuri, Guido Marcucci, Richard Piekarz, Steven M. Devine, Shelley Orwick, Dan Jones, Michael R. Grever, Alice S. Mims, Ramiro Garzon, Nyla A. Heerema
Publikováno v:
Haematologica. 103:982-987
KMT2A partial tandem duplication occurs in approximately 5-10% of patients with acute myeloid leukemia and is associated with adverse prognosis. KMT2A wild type is epigenetically silenced in KMT2A partial tandem duplication; re-expression can be indu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2c0025d27dee42d91bb43ad9955f8f1e
https://doi.org/10.3324/haematol.2017.186890
https://doi.org/10.3324/haematol.2017.186890
Autor:
Richard Stone, Maria R. Baer, Kati Maharry, Heiko Becker, Michael A. Caligiuri, Jessica Kohlschmidt, Klaus H. Metzeler, Ann-Kathrin Eisfeld, Sebastian Schwind, Jason H. Mendler, Bayard L. Powell, Susan P. Whitman, Thomas H. Carter, Il-Kyoo Park, Jonathan E. Kolitz, Andrew J. Carroll, Krzysztof Mrózek, Clara D. Bloomfield, Deedra Nicolet, Guido Marcucci, Stefano Volinia
Publikováno v:
Leukemia
Emerging data demonstrate important roles for the TYRO3/AXL/MERTK receptor tyrosine kinase (TAM RTK) family in diverse cancers. We investigated the prognostic relevance of GAS6 expression, encoding the common TAM RTK ligand, in 270 adults (n=71 aged
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d5d780cf0a2d1091f94fa2d51722285
https://doi.org/10.1038/leu.2013.371
https://doi.org/10.1038/leu.2013.371
Autor:
Robert J. Lee, John S. Nemer, Ramasamy Santhanam, Daniel L. Brook, Jianying Zhang, Mengzi Zhang, G. Marcucci, Xiaoli Zhang, Susan P. Whitman, Michael A. Caligiuri, Guido Marcucci, Xiaojuan Yang, Kathryn E. Dickerson, Kathleen McConnell, William Blum, Adrienne M. Dorrance, Elshafa H. Ahmed, Kelsie M. Bernot, Shujun Liu, Ronald F. Siebenaler, Bethany L. Mundy-Bosse, Nicholas Zorko, Sabrina L Garman, Maura R. Muñoz
Publikováno v:
Blood. 122:3778-3783
The coexpression of the MLL partial tandem duplication (PTD) and the FLT3 internal tandem duplication (ITD) mutations associate with a poor outcome in cytogenetically normal acute myeloid leukemia (AML). In mice, a double knock-in (dKI) of Mll(PTD/wt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c38160f25c47b479bd81a0f4ad3fff41
https://doi.org/10.1182/blood-2013-06-507426
https://doi.org/10.1182/blood-2013-06-507426
Autor:
Il-Kyoo Park, Anjali Mishra, Guido Marcucci, Jason C. Chandler, Michael A. Caligiuri, Susan P. Whitman
Publikováno v:
Blood. 121:2064-2073
Approximately 20% to 25% of patients with acute myeloid leukemia (AML) have a constitutively activated FLT3-internal tandem duplication (FLT3-ITD), and these patients exhibit a poor prognosis. Here, we report that Axl, a receptor tyrosine kinase (RTK
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cec7377b90d5db0f4f6050e0f14cb05
https://doi.org/10.1182/blood-2012-07-444018
https://doi.org/10.1182/blood-2012-07-444018
Autor:
Deedra Nicolet, Ravi Vij, Lai-Chu Wu, William Blum, Ramasamy Santhanam, Kati Maharry, Sebastian Schwind, Anjali Mishra, Heiko Becker, Susan P. Whitman, Houda Alachkar, Christopher Hickey, Anna M. Eiring, Alison Walker, Adrienne M. Dorrance, Danilo Perrotti, John C. Byrd, Xi Zhao, L. James Lee, Krzysztof Mrózek, Guido Marcucci, Ramiro Garzon, Todd A. Fehniger, Michael A. Caligiuri, Clara D. Bloomfield, Yue-Zhong Wu, Hanna S. Radomska
Publikováno v:
Blood. 121:159-169
Recently, we showed that increased miR-181a expression was associated with improved outcomes in cytogenetically normal acute myeloid leukemia (CN-AML). Interestingly, miR-181a expression was increased in CN-AML patients harboring CEBPA mutations, whi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b695b700a5f99d6b81e2efefb4428f2a
https://doi.org/10.1182/blood-2012-05-428573
https://doi.org/10.1182/blood-2012-05-428573
Autor:
Michael D. Radmacher, Sebastian Schwind, Kati Maharry, Susan P. Whitman, Klaus H. Metzeler, Joseph O. Moore, Richard A. Larson, Deedra Nicolet, Meir Wetzler, Andrew J. Carroll, Heiko Becker, Krzysztof Mrózek, Jihane Khalife, Michael A. Caligiuri, Jessica Kohlschmidt, Maria R. Baer, Jonathan E. Kolitz, Bayard L. Powell, Guido Marcucci, Jason H. Mendler, Thomas H. Carter, Clara D. Bloomfield
Publikováno v:
Journal of Clinical Oncology. 30:3109-3118
Purpose To determine the association of RUNX1 mutations with therapeutic outcome in younger and older patients with primary cytogenetically normal acute myeloid leukemia (CN-AML) and with gene/microRNA expression signatures. Patients and Methods Youn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d8ab2fdbf5d77af99cbd8e013b6ec89
https://doi.org/10.1200/jco.2011.40.6652
https://doi.org/10.1200/jco.2011.40.6652