Zobrazeno 1 - 10 of 24 pro vyhledávání: '"Susan P. Foy"'
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Akademický článek
Poxvirus-Based Active Immunotherapy with PD-1 and LAG-3 Dual Immune Checkpoint Inhibition Overcomes Compensatory Immune Regulation, Yielding Complete Tumor Regression in Mice.
Autor: Susan P Foy, Barbara Sennino, Tracy dela Cruz, Joseph J Cote, Evan J Gordon, Felicia Kemp, Veronica Xavier, Alex Franzusoff, Ryan B Rountree, Stefanie J Mandl
Publikováno v: PLoS ONE, Vol 11, Iss 2, p e0150084 (2016)
Poxvirus-based active immunotherapies mediate anti-tumor efficacy by triggering broad and durable Th1 dominated T cell responses against the tumor. While monotherapy significantly delays tumor growth, it often does not lead to complete tumor regressi
Externí odkaz: https://doaj.org/article/cc7e12682bbf4a1697d92a736c69d78a
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3
Poxvirus-based active immunotherapy synergizes with CTLA-4 blockade to increase survival in a murine tumor model by improving the magnitude and quality of cytotoxic T cells
Autor: James Bradley Breitmeyer, Susan P. Foy, Alex Franzusoff, Stefanie Mandl, Evan Gordon, Ryan Rountree, Tracy dela Cruz, Erica Trent, Alain Delcayre, Joseph Cote
Publikováno v: Cancer Immunology, Immunotherapy
The dramatic clinical benefit of immune checkpoint blockade for a fraction of cancer patients suggests the potential for further clinical benefit in a broader cancer patient population by combining immune checkpoint inhibitors with active immunothera
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9395906428049baa5fb1d2ecc978bc58
https://doi.org/10.1007/s00262-016-1816-7
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Abstract 4783: Highly efficient, non-viral precision genome engineering for the generation of personalized neoepitope-specific adoptive T cell therapies
Autor: William Lu, Olivier Dalmas, Fabrizia Urbinati, Michael T. Bethune, Theresa Hunter, Alex Franzusoff, Songming Peng, Diana Nguyen, Susan P. Foy, Robert Moot, Kyle Jacoby, Barbara Sennino, Bhamini Purandare, Adam J. Litterman, Albert K. Tai, Stefanie Mandl, Andrew Conroy
Publikováno v: Cancer Research. 79:4783-4783
Methods used to engineer cells for adoptive cell therapies (ACT) utilizing receptors that are constant across many patients (CAR or shared Ag TCRs) typically rely on Lenti-, retro-, or adeno-associated virus to deliver specificity-altering sequences
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::dbff17c06d9a4ce9ec69b7ed5ecc94ef
https://doi.org/10.1158/1538-7445.am2019-4783
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Poxvirus-Based Active Immunotherapy with PD-1 and LAG-3 Dual Immune Checkpoint Inhibition Overcomes Compensatory Immune Regulation, Yielding Complete Tumor Regression in Mice
Autor: Ryan Rountree, Evan Gordon, Veronica Xavier, Susan P. Foy, Joseph Cote, Stefanie Mandl, Tracy dela Cruz, Barbara Sennino, Alex Franzusoff, Felicia Kemp
Publikováno v: PLoS ONE
PLoS ONE, Vol 11, Iss 2, p e0150084 (2016)
Poxvirus-based active immunotherapies mediate anti-tumor efficacy by triggering broad and durable Th1 dominated T cell responses against the tumor. While monotherapy significantly delays tumor growth, it often does not lead to complete tumor regressi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e13ac4cf6c5b2bc3875904509c1937e1
http://europepmc.org/articles/PMC4765931
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7
Oh the irony: Iron as a cancer cause or cure?
Autor: Susan P. Foy, Vinod Labhasetwar
Publikováno v: Biomaterials. 32:9155-9158
Iron-oxide nanoparticles facilitate cancer diagnosis through enhanced contrast, selectively enhance tumor cell death with magnetic hyperthermia, and improve drug delivery with magnetic drug targeting. One application that remains largely unexplored i
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f754ad905de779d7dfb98500aaab6cd1
https://doi.org/10.1016/j.biomaterials.2011.09.047
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8
Tumor Ablation and Nanotechnology
Autor: Nishanth Krishnamurthy, Rachel L. Manthe, Vinod Labhasetwar, Blanka Sharma, Susan P. Foy
Publikováno v: Molecular Pharmaceutics. 7:1880-1898
Next to surgical resection, tumor ablation is a commonly used intervention in the treatment of solid tumors. Tumor ablation methods include thermal therapies, photodynamic therapy, and reactive oxygen species (ROS) producing agents. Thermal therapies
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc66d0076bac22c5120277f09e3a5ea0
https://doi.org/10.1021/mp1001944
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9
The impact of third molar symptoms, pain, and swelling on oral health-related quality of life
Autor: Susan P. Foy, Daniel A. Shugars, Ceib Phillips, Gary D. Slade, Raymond P. White
Publikováno v: Journal of Oral and Maxillofacial Surgery. 62:1118-1124
Purpose This study was designed to assess the impact of “pain and swelling” associated with third molars on patients’ quality of life before surgery. Patients and Methods The data for these analyses were obtained from a larger ongoing study des
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::955ff07a1617082950702dcb2eb96d8e
https://doi.org/10.1016/j.joms.2003.11.014
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10
The impact of intravenous antibiotics on health-related quality of life outcomes and clinical recovery after third molar surgery
Autor: Raymond P. White, Shawn M. Conrad, Daniel A. Shugars, Ceib Phillips, Robert D. Marciani, Susan P. Foy
Publikováno v: Journal of Oral and Maxillofacial Surgery. 62:15-21
Purpose: We sought to compare recovery for clinical and health-related quality of life (HRQOL) outcomes after third molar surgery in patients treated with or without intravenous antibiotics at surgery. Patients and Methods: Fifty-six patients at leas
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eca61f5e30e18189528888f0995497bc
https://doi.org/10.1016/j.joms.2003.04.003
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