Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Susan P. Crawford"'
Autor:
Alexander Glaser, Zhuqing Shi, Jun Wei, Nadia A. Lanman, Skylar Ladson-Gary, Renee E. Vickman, Omar E. Franco, Susan E. Crawford, S. Lilly Zheng, Simon W. Hayward, William B. Isaacs, Brian T. Helfand, Jianfeng Xu
Publikováno v:
European Urology Open Science, Vol 43, Iss , Pp 54-61 (2022)
Background: The association between benign prostatic hyperplasia (BPH) and prostate cancer (PCa) remains controversial, largely due to a detection bias in traditional observational studies. Objective: To assess the association between BPH and PCa usi
Externí odkaz:
https://doaj.org/article/b38eb71cdebd4aa9be17d3bfc70b3177
Autor:
Renee E. Vickman, LaTayia Aaron-Brooks, Renyuan Zhang, Nadia A. Lanman, Brittany Lapin, Victoria Gil, Max Greenberg, Takeshi Sasaki, Gregory M. Cresswell, Meaghan M. Broman, J. Sebastian Paez, Jacqueline Petkewicz, Pooja Talaty, Brian T. Helfand, Alexander P. Glaser, Chi-Hsiung Wang, Omar E. Franco, Timothy L. Ratliff, Kent L. Nastiuk, Susan E. Crawford, Simon W. Hayward
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
Reduction of systemic autoimmunity using TNF blockers may also reduce inflammatory diseases in other organs. Here, the authors use a patient database and scRNA-seq to link autoimmune diseases to benign prostatic hyperplasia (BPH), and demonstrate tha
Externí odkaz:
https://doaj.org/article/572e6df1a2f4471bb53b3a820ff54a37
Autor:
Rida Iftikhar, Harrison M. Penrose, Angelle N. King, Joshua S. Samudre, Morgan E. Collins, Alifiani B. Hartono, Sean B. Lee, Frank Lau, Melody Baddoo, Erik F. Flemington, Susan E. Crawford, Suzana D. Savkovic
Publikováno v:
Oncogenesis, Vol 10, Iss 11, Pp 1-10 (2021)
Abstract Obesity is a worldwide epidemic associated with increased risk and progression of colon cancer. Here, we aimed to determine the role of adipose triglyceride lipase (ATGL), responsible for intracellular lipid droplet (LD) utilization, in obes
Externí odkaz:
https://doaj.org/article/dad0fa3c4c914a0ebba7e45d5f2c7f93
Autor:
Anastasia C. Hepburn, Emma L. Curry, Mohammad Moad, Rebecca E. Steele, Omar E. Franco, Laura Wilson, Parmveer Singh, Adriana Buskin, Susan E. Crawford, Luke Gaughan, Ian G. Mills, Simon W. Hayward, Craig N. Robson, Rakesh Heer
Publikováno v:
Stem Cells Translational Medicine, Vol 9, Iss 7, Pp 734-745 (2020)
Abstract Primary culture of human prostate organoids and patient‐derived xenografts is inefficient and has limited access to clinical tissues. This hampers their use for translational study to identify new treatments. To overcome this, we establish
Externí odkaz:
https://doaj.org/article/1a016c78ab2e4635979543ad1a0a990f
Autor:
Harrison M. Penrose, Chloe Cable, Sandra Heller, Nathan Ungerleider, Hani Nakhoul, Melody Baddoo, Alifiani B. Hartono, Sean B. Lee, Matthew E. Burow, Erik F. Flemington, Susan E. Crawford, Suzana D. Savkovic
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 7, Iss 2, Pp 391-408 (2019)
Background & Aims: Diminished forkhead box O3 (FOXO3) function drives inflammation and cancer growth; however, mechanisms fostering these pathobiologies are unclear. Here, we aimed to identify in colon loss of FOXO3-dependent cellular and molecular c
Externí odkaz:
https://doaj.org/article/7337e8aa807f4d11a94daa9ce23793f7
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 14, p 7745 (2022)
The retinal pigment epithelium (RPE) expresses the Serpinf1 gene to produce pigment epithelium-derived factor (PEDF), a retinoprotective protein that is downregulated with cell senescence, aging and retinal degenerations. We determined the expression
Externí odkaz:
https://doaj.org/article/c6cd5e8742bd47999bc1367020bf8b65
Autor:
Rida Iftikhar, Harrison M. Penrose, Angelle N. King, Joshua S. Samudre, Morgan E. Collins, Alifiani B. Hartono, Sean B. Lee, Frank Lau, Melody Baddoo, Erik F. Flemington, Susan E. Crawford, Suzana D. Savkovic
Publikováno v:
Oncogenesis, Vol 11, Iss 1, Pp 1-1 (2022)
Externí odkaz:
https://doaj.org/article/df3e440f84514614aa5dd372b8cc26ab
Autor:
Susan Y. Crawford
Publikováno v:
Journal of the Medical Library Association, Vol 104, Iss 1 (2016)
This commentary examines the evolution of the biomedical communications system in the Western world. The examination touches on many aspects, including the application of new technology, the interoperative relationship between publications and data,
Externí odkaz:
https://doaj.org/article/ac6738187e784b98934b2f24607a909a
Publikováno v:
Journal of Obstetrics and Gynaecology Canada. 41:1734-1741
Objective The purpose of this study was to describe associations between episiotomy at the time of forceps or vacuum-assisted delivery and obstetrical anal sphincter injuries (OASIS). Methods This population-based retrospective cohort study used deli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::429423ecd506408241a85bf365d750b4
https://doi.org/10.1016/j.jogc.2019.02.016
https://doi.org/10.1016/j.jogc.2019.02.016
Autor:
Sofia Halin, Stina Häggström Rudolfsson, Jennifer A. Doll, Susan E. Crawford, Pernilla Wikström, Anders Bergh
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 12, Iss 4, Pp 336-345 (2010)
Pigment epithelium-derived factor (PEDF) is a potent inhibitor of angiogenesis but whether it has additional effects on the tumor microenvironment is largely unexplored. We show that overexpression of PEDF in orthotopic MatLyLu rat prostate tumors in
Externí odkaz:
https://doaj.org/article/32d407ebc3594ede8b331d49ecfbc51a