Zobrazeno 1 - 10
of 220
pro vyhledávání: '"Susan P Lees-Miller"'
Autor:
Frantisek Filandr, Vladimir Sarpe, Shaunak Raval, D. Alex Crowder, Morgan F. Khan, Pauline Douglas, Stephen Coales, Rosa Viner, Aleem Syed, John A. Tainer, Susan P. Lees-Miller, David C. Schriemer
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract We present a hydrogen/deuterium exchange workflow coupled to tandem mass spectrometry (HX-MS2) that supports the acquisition of peptide fragment ions alongside their peptide precursors. The approach enables true auto-curation of HX data by m
Externí odkaz:
https://doaj.org/article/8c900839ad1c4b10a419586ee7d79785
Autor:
Susan P Lees-Miller
Publikováno v:
PLoS Genetics, Vol 10, Iss 8, p e1004598 (2014)
Externí odkaz:
https://doaj.org/article/6000ffbb3cd8452db51cd8c4f5309855
Autor:
May Shawi, Tsz Wai Chu, Veronica Martinez-Marignac, Y Yu, Sergei M Gryaznov, James B Johnston, Susan P Lees-Miller, Sarit E Assouline, Chantal Autexier, Raquel Aloyz
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e70428 (2013)
We report that Imetelstat, a telomerase inhibitor that binds to the RNA component of telomerase (hTR), can sensitize primary CLL lymphocytes to fludarabine in vitro. This effect was observed in lymphocytes from clinically resistant cases and with cyt
Externí odkaz:
https://doaj.org/article/2b8aed91c37f463999fd2687df61892c
Autor:
Frantisek Filandr, Vladimir Sarpe, Shaunak Raval, D. Alex Crowder, Morgan F. Khan, Pauline Douglas, Stephen Coales, Rosa Viner, Aleem Syed, John A. Tainer, Susan P. Lees-Miller, David C. Schriemer
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/165f5b3a8f494e12ab6cbfdea6535412
Autor:
Siyu Chen, Alex Vogt, Linda Lee, Tasmin Naila, Ryan McKeown, Alan E Tomkinson, Susan P Lees-Miller, Yuan He
Publikováno v:
Science Advances. 9
DNA double-strand breaks (DSBs), one of the most cytotoxic forms of DNA damage, can be repaired by the tightly regulated nonhomologous end joining (NHEJ) machinery (Stinson and Loparo and Zhao et al. ). Core NHEJ factors form an initial long-range (L
Autor:
Puri Fortes, Susan P. Lees-Miller, Oscar Llorca, Fernando Moreno-Herrero, Gareth Williams, Bruno Sangro, Jessica Zucman-Rossi, Stefano Caruso, Linda Lee, Raquel Arribas-Bosacoma, Laura Prats-Mari, Christopher McCoy, Clara Aicart-Ramos, Sara de Bragança, Eva M. Martín-Cuevas, Nerea Razquin, Ángel Rivera-Calzada, Mikel Marín-Baquero, Juan P. Unfried
Long noncoding RNAs (lncRNA) are emerging as key players in cancer as parts of poorly understood molecular mechanisms. Here, we investigated lncRNAs that play a role in hepatocellular carcinoma (HCC) and identified NIHCOLE, a novel lncRNA induced in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ddc8d809a7727844f6b3daa38980da84
https://doi.org/10.1158/0008-5472.c.6512958.v1
https://doi.org/10.1158/0008-5472.c.6512958.v1
Autor:
Susan P. Lees-Miller, D. Gwyn Bebb, Mark J. O'Connor, Alberto Zamò, Ali G. Turhan, Huong Muzik, Chris T. Williamson
Poly(ADP-ribose) polymerase-1 (PARP-1) inhibition is toxic to cells with mutations in the breast and ovarian cancer susceptibility genes BRCA1 or BRCA2, a concept termed synthetic lethality. However, whether this approach is applicable to other human
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5abdc07d0b58ece6c71e611d15232e50
https://doi.org/10.1158/1535-7163.c.6531851.v1
https://doi.org/10.1158/1535-7163.c.6531851.v1
Autor:
Puri Fortes, Susan P. Lees-Miller, Oscar Llorca, Fernando Moreno-Herrero, Gareth Williams, Bruno Sangro, Jessica Zucman-Rossi, Stefano Caruso, Linda Lee, Raquel Arribas-Bosacoma, Laura Prats-Mari, Christopher McCoy, Clara Aicart-Ramos, Sara de Bragança, Eva M. Martín-Cuevas, Nerea Razquin, Ángel Rivera-Calzada, Mikel Marín-Baquero, Juan P. Unfried
Supplementary Figures S1-S7
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c183ccf28669fff390b5ca9cc5b33ca
https://doi.org/10.1158/0008-5472.22428237
https://doi.org/10.1158/0008-5472.22428237
Autor:
Susan P. Lees-Miller, D. Gwyn Bebb, Mark J. O'Connor, Alberto Zamò, Ali G. Turhan, Huong Muzik, Chris T. Williamson
Supplementary Table 1, Figures 1-4 from ATM Deficiency Sensitizes Mantle Cell Lymphoma Cells to Poly(ADP-Ribose) Polymerase-1 Inhibitors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0764b0544a9de34bc102c80aa4105897
https://doi.org/10.1158/1535-7163.22485248.v1
https://doi.org/10.1158/1535-7163.22485248.v1
Autor:
Puri Fortes, Susan P. Lees-Miller, Oscar Llorca, Fernando Moreno-Herrero, Gareth Williams, Bruno Sangro, Jessica Zucman-Rossi, Stefano Caruso, Linda Lee, Raquel Arribas-Bosacoma, Laura Prats-Mari, Christopher McCoy, Clara Aicart-Ramos, Sara de Bragança, Eva M. Martín-Cuevas, Nerea Razquin, Ángel Rivera-Calzada, Mikel Marín-Baquero, Juan P. Unfried
Supplementary Table S1A-E
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d068e7ee282ec2e9c05e80112a542ee
https://doi.org/10.1158/0008-5472.22428228.v1
https://doi.org/10.1158/0008-5472.22428228.v1