Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Susan Obeid"'
Autor:
Susan Obeid, Jo Alen, Van Hung Nguyen, Van Cuong Pham, Philip Meuleman, Christophe Pannecouque, Thanh Nguyen Le, Johan Neyts, Wim Dehaen, Jan Paeshuyse
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e81783 (2013)
We reported previously that Artemisinin (ART), a widely used anti-malarial drug, is an inhibitor of in vitro HCV subgenomic replicon replication. We here demonstrate that ART exerts its antiviral activity also in hepatoma cells infected with full len
Externí odkaz:
https://doaj.org/article/73e0fc56ed274387bcb6e5c66d2f31bd
Autor:
Susan Obeid, Alfons Van Lommel, Johan Neyts, Jolien Vanhove, Frederik Nevens, Catherine M. Verfaillie, Philip Roelandt, Yaakov Nahmias, Jan Paeshuyse
Publikováno v:
Journal of Hepatology. 57:246-251
Background & Aims Worldwide, about 180million people are chronically infected with the hepatitis C virus (HCV). Current in vitro culture systems for HCV depend chiefly on human hepatoma cell lines. Although primary human hepatocytes support HCV infec
Autor:
Steven J. Moss, Barrie Wilkinson, Teresa A. Foster, Philippe Gallay, Ming-Qiang Zhang, Mahmood Piraee, Dipen Suthar, Jan Paeshuyse, Michael Bobardt, Matthew Alan Gregory, Udayan Chatterji, Tony Warneck, Susan Obeid, Pieter Leyssen, Mohammad Nur-e-Alam, Johan Neyts, Nigel Coates
Publikováno v:
Antimicrobial Agents and Chemotherapy. 55:1975-1981
Cyclophilin inhibitors currently in clinical trials for hepatitis C virus (HCV) are all analogues of cyclosporine (CsA). Sanglifehrins are a group of naturally occurring cyclophilin binding polyketides that are structurally distinct from the cyclospo
Autor:
Susan Obeid, David Durantel, Johan Neyts, Svetlana S. Printsevskaya, Eugenia N. Olsufyeva, Maria N. Preobrazhenskaya, Kai Dallmeier, Fabien Zoulim, Jan Paeshuyse
Publikováno v:
Journal of Antimicrobial Chemotherapy
Objectives Some semi-synthetic derivatives of glycopeptide antibiotics have been shown to exert in vitro antiviral activity against HIV and coronaviruses. Here we report and characterize the in vitro anti-hepatitis C virus (HCV) activity of several s
Autor:
Inge Vliegen, Fabien Zoulim, Jan Paeshuyse, Susan Obeid, Leen Delang, Johan Neyts, I. David Durantel, Anne Op De Beeck, Pieter Leyssen
Publikováno v:
Hepatology. 50:6-16
Statins are 3-hydroxyl-3-methylglutaryl coenzyme A (HMG CoA) reductase inhibitors used for the treatment of hypercholesterolemia. It was recently reported that statins inhibit in vitro hepatitis C virus (HCV) RNA replication. We here report that, of
Autor:
Marouane Melloul, Tahar Bajjou, Susan Obeid, Lahoussine Fathallah, Elmostafa El Fahime, A. Laraqui, Idriss Lahlou-Amine, Hicham El Rhaffouli
Publikováno v:
Current microbiology. 68(3)
To study genetic evolution of Moroccan influenza A(H1N1)pdm09 virus strains, we conducted a molecular characterization of the hemagglutinin gene subunit 1 (HA1) of 36 influenza A(H1N1)pdm09 virus strains. The stains were collected from patients in Ra
Autor:
Jolien Vanhove, Yaakov Nahmias, Jan Paeshuyse, Philip Roelandt, Alfons Van Lommel, Catherine M. Verfaillie, Susan Obeid, Johan Neyts, Frederik Nevens
Publikováno v:
Journal of Hepatology. 58:199-200
Autor:
Frederik Nevens, Catherine M. Verfaillie, Kim Vanuytsel, Jolien Vanhove, Susanna Raitano, A Van Lommerl, Johan Neyts, Yaakov Nahmias, Jan Paeshuyse, Philip Roelandt, Susan Obeid
Publikováno v:
Journal of Hepatology. 56:S54-S55
Inhibition of Hepatitis C Virus Replication by Semisynthetic Derivatives of Glycopeptide Antibiotics
Autor:
Leen Delang, Jan Paeshuyse, Maria N. Preobrazhenskaya, Svetlana E. Solovieva, Susan Obeid, Jan Balzarini, Johan Neyts, Svetlana S. Printsevskaya, Eugenia N. Olsufyeva, Alfons Van Lommel
Publikováno v:
Antiviral Research. 86:A40-A41
Autor:
Wim Dehaen, Christophe Pannecouque, Johan Neyts, Thanh Nguyen Le, Jo Alen, Philip Meuleman, Van Hung Nguyen, Jan Paeshuyse, Van Cuong Pham, Susan Obeid
Publikováno v:
PLoS ONE
PLoS ONE, Vol 8, Iss 12, p e81783 (2013)
PLOS ONE
PLoS ONE, Vol 8, Iss 12, p e81783 (2013)
PLOS ONE
We reported previously that Artemisinin (ART), a widely used anti-malarial drug, is an inhibitor of in vitro HCV subgenomic replicon replication. We here demonstrate that ART exerts its antiviral activity also in hepatoma cells infected with full len