Zobrazeno 1 - 10
of 224
pro vyhledávání: '"Susan N Chi"'
Autor:
Suzanne J. Forrest, Hersh Gupta, Abigail Ward, Yvonne Y. Li, Duong Doan, Alyaa Al-Ibraheemi, Sanda Alexandrescu, Pratiti Bandopadhayay, Suzanne Shusterman, Elizabeth A. Mullen, Natalie B. Collins, Susan N. Chi, Karen D. Wright, Priti Kumari, Tali Mazor, Keith L. Ligon, Priyanka Shivdasani, Monica Manam, Laura E. MacConaill, Evelina Ceca, Sidney N. Benich, Wendy B. London, Richard L. Schilsky, Suanna S. Bruinooge, Jaime M. Guidry Auvil, Ethan Cerami, Barrett J. Rollins, Matthew L. Meyerson, Neal I. Lindeman, Bruce E. Johnson, Andrew D. Cherniack, Alanna J. Church, Katherine A. Janeway
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-11 (2024)
Abstract To inform clinical trial design and real-world precision pediatric oncology practice, we classified diagnoses, assessed the landscape of mutations, and identified genomic variants matching trials in a large unselected institutional cohort of
Externí odkaz:
https://doaj.org/article/4017a15f72474d229f7c23ceb2ec8422
Autor:
Ajami Gikandi, Susan N. Chi, Kee Kiat Yeo, Allison F. O'Neill, David S. Shulman, Steven G. DuBois, Natalie B. Collins
Publikováno v:
Cancer Medicine, Vol 13, Iss 8, Pp n/a-n/a (2024)
Abstract Background Immune checkpoint inhibitors (ICI) have improved outcomes in a variety of adult cancers and are prescribed with increasing frequency across oncology. However, patterns of off‐label use of ICI in pediatrics remain unclear. Method
Externí odkaz:
https://doaj.org/article/c0b09fda39d84998acabc99d862c2cad
Autor:
Suzanne J. Forrest, Hersh Gupta, Abigail Ward, Yvonne Y. Li, Duong Doan, Alyaa Al-Ibraheemi, Sanda Alexandrescu, Pratiti Bandopadhayay, Suzanne Shusterman, Elizabeth A. Mullen, Natalie B. Collins, Susan N. Chi, Karen D. Wright, Priti Kumari, Tali Mazor, Keith L. Ligon, Priyanka Shivdasani, Monica Manam, Laura E. MacConaill, Evelina Ceca, Sidney N. Benich, Wendy B. London, Richard L. Schilsky, Suanna S. Bruinooge, Jaime M. Guidry Auvil, Ethan Cerami, Barrett J. Rollins, Matthew L. Meyerson, Neal I. Lindeman, Bruce E. Johnson, Andrew D. Cherniack, Alanna J. Church, Katherine A. Janeway
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/fb4f1740ba5f49008685d912d84b0bbb
Autor:
Sabine Mueller, Jared M. Taitt, Javier E. Villanueva-Meyer, Erin R. Bonner, Takahide Nejo, Rishi R. Lulla, Stewart Goldman, Anu Banerjee, Susan N. Chi, Nicholas S. Whipple, John R. Crawford, Karen Gauvain, Kellie J. Nazemi, Payal B. Watchmaker, Neil D. Almeida, Kaori Okada, Andres M. Salazar, Ryan D. Gilbert, Javad Nazarian, Annette M. Molinaro, Lisa H. Butterfield, Michael D. Prados, Hideho Okada
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 12 (2022)
Externí odkaz:
https://doaj.org/article/70b2f3c41d9640fc9b62b78460da04ba
Autor:
David S. Shulman, Lulla V. Kiwinda, Stacey Edwards, Catherine M. Clinton, Sarah Hunt, Lianne Greenspan, Kristen D. Lawler, Gregory Reaman, Hasan Al‐Sayegh, Kira Bona, Allison F. O'Neill, Suzanne Shusterman, Katherine A. Janeway, Andrew E. Place, Susan N. Chi, Clement Ma, Steven G. DuBois
Publikováno v:
Cancer Medicine, Vol 10, Iss 7, Pp 2310-2318 (2021)
Abstract Background Single patient Investigational New Drug (IND) applications are one mechanism through which experimental therapies are accessed for children with cancer. The landscape of use, outcomes, and toxicity from single patient INDs remains
Externí odkaz:
https://doaj.org/article/a55985f140e94952817cff413dfa8e6f
Autor:
Andrew L Hong, Yuen-Yi Tseng, Jeremiah A Wala, Won-Jun Kim, Bryan D Kynnap, Mihir B Doshi, Guillaume Kugener, Gabriel J Sandoval, Thomas P Howard, Ji Li, Xiaoping Yang, Michelle Tillgren, Mahmhoud Ghandi, Abeer Sayeed, Rebecca Deasy, Abigail Ward, Brian McSteen, Katherine M Labella, Paula Keskula, Adam Tracy, Cora Connor, Catherine M Clinton, Alanna J Church, Brian D Crompton, Katherine A Janeway, Barbara Van Hare, David Sandak, Ole Gjoerup, Pratiti Bandopadhayay, Paul A Clemons, Stuart L Schreiber, David E Root, Prafulla C Gokhale, Susan N Chi, Elizabeth A Mullen, Charles WM Roberts, Cigall Kadoch, Rameen Beroukhim, Keith L Ligon, Jesse S Boehm, William C Hahn
Publikováno v:
eLife, Vol 8 (2019)
Renal medullary carcinoma (RMC) is a rare and deadly kidney cancer in patients of African descent with sickle cell trait. We have developed faithful patient-derived RMC models and using whole-genome sequencing, we identified loss-of-function intronic
Externí odkaz:
https://doaj.org/article/ea9c3a1d96864bb8bbdbc626e575f019
Autor:
Susan N Chi, Joanna S Yi, P Mickey Williams, Sinchita Roy-Chowdhuri, David R Patton, Brent D Coffey, Joel M Reid, Jin Piao, Lauren Saguilig, Todd A Alonzo, Stacey L Berg, Nilsa C Ramirez, Alok Jaju, Joyce C Mhlanga, Elizabeth Fox, Douglas S Hawkins, Margaret M Mooney, Naoko Takebe, James V Tricoli, Katherine A Janeway, Nita L Seibel, D Williams Parsons
Publikováno v:
JNCI: Journal of the National Cancer Institute.
Background NCI-COG Pediatric MATCH assigns patients aged 1-21 years with refractory solid tumors, brain tumors, lymphomas, and histiocytic disorders to phase II trials of molecularly targeted therapies based on detection of pre-defined genetic altera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::287b50580ea01adeaefb52fc91ae7354
https://doi.org/10.1093/jnci/djad085
https://doi.org/10.1093/jnci/djad085
Autor:
Tom Rosenberg, Kee Kiat Yeo, Audrey Mauguen, Sanda Alexandrescu, Sanjay P Prabhu, Jessica W Tsai, Seth Malinowski, Mrinal Joshirao, Karishma Parikh, Sameer Farouk Sait, Marc K Rosenblum, Jamal K Benhamida, George Michaiel, Hung N Tran, Sonika Dahiya, Kara Kachurak, Gregory K Friedman, Julie I Krystal, Michael A Huang, Ashley S Margol, Karen D Wright, Dolly Aguilera, Tobey J MacDonald, Susan N Chi, Matthias A Karajannis
Publikováno v:
Neuro Oncol
Background The prognosis for patients with pediatric high-grade glioma (pHGG) is poor despite aggressive multimodal therapy. Objective responses to targeted therapy with BRAF inhibitors have been reported in some patients with recurrent BRAF-mutant p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7f4c96c60e61ce31e344d50486644e5
https://pubmed.ncbi.nlm.nih.gov/35750023
https://pubmed.ncbi.nlm.nih.gov/35750023
Autor:
A. Thomas Look, Holger Sudhoff, Jon C. Aster, Susan N. Chi, Peter Goon, Viyof Ful Flavian, Matthias Schürmann, Mark W. Zimmerman, Sarah Gendreizig, Senyao Shao, Felix Oppel
Supplementary Data from p53 Pathway Inactivation Drives SMARCB1-deficient p53-wildtype Epithelioid Sarcoma Onset Indicating Therapeutic Vulnerability Through MDM2 Inhibition
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbebe9035bfdea25a65ea647b50bc6c9
https://doi.org/10.1158/1535-7163.22523211.v1
https://doi.org/10.1158/1535-7163.22523211.v1
Autor:
Susan N. Chi, Sudha Parasuraman, Jason R. Dobson, Suraj G. Bhansali, Alessandro Matano, Marlyane Motta, Giles W. Robinson, Thomas Cash, Shakeel Modak, Andrew D.J. Pearson, Aurélien Marabelle, Nicholas G. Gottardo, James I. Geller, Matthias Fischer, Steven G. DuBois, Franck Bourdeaut, Birgit Geoerger
Pub fees email yes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5d51f0ad014a0e5d759351e185cfaf4
https://doi.org/10.1158/1078-0432.22467020.v1
https://doi.org/10.1158/1078-0432.22467020.v1