Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Susan Masewicz"'
Publikováno v:
European Journal of Immunology. 34:3337-3345
Altered peptide ligands derived from T cell-reactive self antigens have been shown to be protective therapeutic agents in animal models of autoimmunity. In this study we identified several altered peptide ligands derived from the type 1 diabetes-asso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73c16cf49e87b7e8d599308797fa8368
https://doi.org/10.1002/eji.200425535
https://doi.org/10.1002/eji.200425535
Autor:
L Moriarity, Susan Masewicz, E Swanson, Antonis K. Moustakas, George K. Papadopoulos, Gerald T. Nepom
Publikováno v:
Tissue Antigens. 59:101-112
Human CD4 T cell responses to an epitope of hGAD65 (GAD = glutamic acid decarboxylase), residues 555-567, are modulated by interaction with an altered peptide ligand containing modifications at TCR contact residues. Using different HLA-DR4 molecules
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::361d30f031ea3d292961e72af0e61275
https://doi.org/10.1034/j.1399-0039.2002.590205.x
https://doi.org/10.1034/j.1399-0039.2002.590205.x
Autor:
Susan Masewicz, Niecey Meldrum, Lakshmi K. Gaur, Gerald T. Nepom, Lori Moriarity, Vivian H. Gersuk, William Hagopian
Publikováno v:
Autoimmunity. 34:231-240
Complex protein antigens contain multiple potential T cell recognition epitopes, which are generated through a processing pathway involving partial antigen degradation via proteases, binding to MHC molecules, and display on the APC surface, followed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0f4fadf2b30df5c4ee40d5206cfe45a
https://doi.org/10.3109/08916930109014692
https://doi.org/10.3109/08916930109014692
Autor:
Derek G. Doherty, Julie E. Penzotti, David M. Koelle, William W. Kwok, Terry P. Lybrand, Susan Masewicz, Gerald T. Nepom
Publikováno v:
The Journal of Immunology. 161:3527-3535
TCR engagement of peptide-MHC class II ligands involves specific contacts between the TCR and residues on both the MHC and peptide molecules. We have used molecular modeling and assays of peptide binding and T cell function to characterize these inte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::810923979de64132ac785baf3fed1a8d
https://doi.org/10.4049/jimmunol.161.7.3527
https://doi.org/10.4049/jimmunol.161.7.3527
Autor:
Katsuo Yamanaka, Eric Mickelson, Frank Smith, Gerald T. Nepom, William W. Kwok, Susan Masewicz
Publikováno v:
Transplantation. 55:1167-1175
Immune recognition of foreign HLA molecules is initiated by T cell recognition mediated by alloreactive T cell receptor (TCR) molecules. We analyzed the diversity of TCR expression in the clinical setting of allorecognition in a patient with acute gr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d868548cd796907224dce3247b00190f
https://doi.org/10.1097/00007890-199305000-00043
https://doi.org/10.1097/00007890-199305000-00043
Autor:
Susan Masewicz, Niels Ødum, John A. Hansen, Eric Mickelson, Paul J. Martin, Jeffrey A. Ledbetter
Publikováno v:
Human Immunology. 36:142-148
Bacterial superantigens have two immunologically important features. They bind MHC class II molecules and stimulate T cells bearing certain V beta TCR phenotypes. Superantigens such as SEA, SEB, and TSST bind to each of the three HLA class II isotype
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a22cc2e5c0df412da2f747b72bf6b0ff
https://doi.org/10.1016/0198-8859(93)90117-j
https://doi.org/10.1016/0198-8859(93)90117-j
Autor:
J. Lee Nelson, Thomas D. Koepsell, Eric Mickelson, Carin E. Dugowson, John A. Hansen, Rob Harrington, Susan Masewicz
Publikováno v:
Tissue Antigens. 38:145-151
HLA-DR4 has been shown to be associated with risk for developing rheumatoid arthritis (RA) in multiple populations and racial groups. The allelic variants of DR4 share the DR4 serologic specificity but differ by 1 to 3 amino acids in the third hyperv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b1a52344bf5b225a5466d8ad02571400
https://doi.org/10.1111/j.1399-0039.1991.tb01888.x
https://doi.org/10.1111/j.1399-0039.1991.tb01888.x
Autor:
Gary L. Schieven, John A. Hansen, Niels Ødum, Jeffrey A. Ledbetter, Susan Masewicz, Paul J. Martin
Publikováno v:
Tissue Antigens. 38:72-77
Crosslinking HLA-DR molecules by monoclonal antibodies (mAb) induces protein tyrosine phosphorylation and results in a secondary elevation of free cytoplasmic Ca2+ concentration ([Ca2+]i) in activated human T cells. Here we have studied the effect of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ee6899cadb143e6566954e6b0e0d685
https://doi.org/10.1111/j.1399-0039.1991.tb01883.x
https://doi.org/10.1111/j.1399-0039.1991.tb01883.x
Publikováno v:
Human Immunology. 30:32-40
HLA-DQw3 is a broadly defined alloantigen that has been subdivided by serological, biochemical, and molecular methods into three distinct specificities: DQw7, DQw8, and DQw9. In order to characterize functionally relevant structural polymorphisms wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fecd9844cebd2dba7a021c50e1e839c9
https://doi.org/10.1016/0198-8859(91)90068-k
https://doi.org/10.1016/0198-8859(91)90068-k
Autor:
Gerald T. Nepom, Effie W. Petersdorf, John A. Hansen, Anajane G. Smith, Paul J. Martin, Eric Mickelson, Susan Masewicz
Publikováno v:
Human Immunology. 32:229-233
Alloreactive T-cell clones were used to study allodeterminants associated with the HLA-DR1, DR4 and -DRw14 allelic families. Three clones derived by priming against the DR4,Dw14 alloantigen were tested against a panel of HLA-D homozygous B-cell lines
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47193f999dfbb08d7a170b1a5f7cce77
https://doi.org/10.1016/0198-8859(91)90060-m
https://doi.org/10.1016/0198-8859(91)90060-m