Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Susan M. Steenbergen"'
Publikováno v:
Journal of Bacteriology. 198:2803-2809
The sialic acids ( N -acylneuraminates) are a group of nine-carbon keto-sugars existing mainly as terminal residues on animal glycoprotein and glycolipid carbohydrate chains. Bacterial commensals and pathogens exploit host sialic acids for nutrition,
Autor:
Eric R. Vimr, Susan M. Steenbergen
Publikováno v:
Molecular Microbiology
Capsular polysaccharides are important virulence determinants in a wide range of invasive infectious diseases. Although capsule synthesis has been extensively investigated, understanding polysaccharide export from the cytoplasm to the external enviro
Autor:
Susan M. Steenbergen, Eric R. Vimr
Publikováno v:
Molecular Microbiology. 60:828-837
Escherichia coli K1 is part of a reservoir of adherent, invasive facultative pathogens responsible for a wide range of human and animal disease including sepsis, meningitis, urinary tract infection and inflammatory bowel syndrome. A prominent virulen
Publikováno v:
Molecular Microbiology. 50:961-975
A variety of pathogens or commensals use at least one of four distinct mechanisms for decorating their surfaces with sialic acid as a strategy to avoid, subvert or inhibit host innate immunity. The metabolism of sialic acid thus is central to a range
Publikováno v:
Molecular Microbiology. 36:1113-1123
Many bacterial commensals and pathogens use the sialic acids as carbon and nitrogen sources. In Escherichia coli, the breakdown of these sugars is catalysed by gene products of the nan (Nacylneuraminate) operon; other microorganisms may use a similar
NanR, one of >8,500 GntR superfamily helix-turn-helix transcriptional regulators, controls expression of the genes required for catabolism of sialic acids in Escherichia coli . It is predicted to do the same in related bacteria harboring orthologs of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a0572d3606e5acbf12ac52aceb9869f
https://europepmc.org/articles/PMC3807447/
https://europepmc.org/articles/PMC3807447/
Autor:
Susan M. Steenbergen, Eric R. Vimr
Publikováno v:
Methods in Molecular Biology ISBN: 9781627032445
Polysialic acid capsules are the major virulence factors in Escherichia coliK1, K92, and groups B and C meningococci. The sialic acid monomers (2-keto-3-deoxy-5-acetamido-7,8,9-D-glycero-D-galacto-nonulosonic acids) comprising these homopolymeric pol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb2a262278bf11d9b2b7690043a62742
https://europepmc.org/articles/PMC4085740/
https://europepmc.org/articles/PMC4085740/
Publikováno v:
Journal of Clinical Microbiology. 34:3035-3039
A more rapid, accurate method to detect toxigenic Pasteurella multocida is needed for improved clinical diagnosis, farm biosecurity, and epidemiological studies. Toxigenic and nontoxigenic P. multocida isolates cannot be differentiated by morphology
Publikováno v:
Journal of Industrial Microbiology. 15:352-360
The extracellular polysaccharides elaborated by most or all bacterial species function in cell-to-cell and cell-substratum adhesion, cell signaling, and avoidance or inhibition of noxious agents in animal hosts or free-living environments. Recent adv
Publikováno v:
Journal of Bacteriology. 177:6005-6010
Catabolism of sialic acids by Escherichia coli requires the genes nanA and nanT, which were previously mapped between argG and rpoN (E.R. Vimr and F.A. Troy, J. Bacteriol. 164:845-853, 1985). This organization is confirmed and extended by physical ma