Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Susan M. Poulsen"'
Publikováno v:
Molecular Microbiology. 41:1091-1099
The pleuromutilin antibiotic derivatives, tiamulin and valnemulin, inhibit protein synthesis by binding to the 50S ribosomal subunit of bacteria. The action and binding site of tiamulin and valnemulin was further characterized on Escherichia coli rib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::43154731648245becd26fd4c4d758013
https://doi.org/10.1046/j.1365-2958.2001.02595.x
https://doi.org/10.1046/j.1365-2958.2001.02595.x
Resistance to the peptidyl transferase inhibitor tiamulin caused by mutation of ribosomal protein L3
Publikováno v:
Bøsling, J, Poulsen, S M, Vester, B & Long, K S 2003, ' Resistance to the peptidyl transferase inhibitor tiamulin caused by mutation of ribosomal protein L3 ', Antimicrobial Agents and Chemotherapy, vol. 47, pp. 2892-96 . https://doi.org/10.1128/AAC.47.9.2892-2896.2003
The antibiotic tiamulin targets the 50S subunit of the bacterial ribosome and interacts at the peptidyl transferase center. Tiamulin-resistant Escherichia coli mutants were isolated in order to elucidate mechanisms of resistance to the drug. No mutat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8bbdbbd70f0eb1d66715385c867be03
https://portal.findresearcher.sdu.dk/da/publications/1a419db0-ba9a-11dc-9626-000ea68e967b
https://portal.findresearcher.sdu.dk/da/publications/1a419db0-ba9a-11dc-9626-000ea68e967b
Publikováno v:
Poulsen, S M, Kofoed, C & Vester, B 2000, ' Inhibition of the ribosomal peptidyl transferase reaction by the mycarose moiety of the antibiotics carbomycin, spiramycin and tylosin. ', Journal of Molecular Biology, vol. 304, no. 3, pp. 471-81 . https://doi.org/10.1006/jmbi.2000.4229
Udgivelsesdato: 2000-Dec-1 Many antibiotics, including the macrolides, inhibit protein synthesis by binding to ribosomes. Only some of the macrolides affect the peptidyl transferase reaction. The 16-member ring macrolide antibiotics carbomycin, spira
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83e85060270257f94c685fb05331ac2a
https://pubmed.ncbi.nlm.nih.gov/11090288
https://pubmed.ncbi.nlm.nih.gov/11090288