Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Susan M. Mockus"'
Autor:
David P. Hill, Akeena Harper, Joan Malcolm, Monica S. McAndrews, Susan M. Mockus, Sara E. Patterson, Timothy Reynolds, Erich J. Baker, Carol J. Bult, Elissa J. Chesler, Judith A. Blake
Publikováno v:
BMC Cancer, Vol 19, Iss 1, Pp 1-13 (2019)
Abstract Background Understanding mechanisms underlying specific chemotherapeutic responses in subtypes of cancer may improve identification of treatment strategies most likely to benefit particular patients. For example, triple-negative breast cance
Externí odkaz:
https://doaj.org/article/910d832b274049c5b00a00bab22501ed
Autor:
Stephen A. Whelan, Nathan Hendricks, Zachary L. Dwight, Qin Fu, Annie Moradian, Jennifer E. Van Eyk, Susan M. Mockus
SummaryTelehealth, accessing healthcare and wellness remotely, should be a cost effective and efficient way for individuals to receive care. The convenience of having a robust remote collection device for blood tests will facilitate access to precisi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::68f1020b2927f7000fe78ca8c1321410
https://doi.org/10.1101/2023.02.04.23285394
https://doi.org/10.1101/2023.02.04.23285394
Autor:
Erich J. Baker, Monica S. McAndrews, Susan M. Mockus, David P. Hill, Elissa J. Chesler, Timothy Reynolds, Carol J. Bult, Joan Malcolm, Sara E. Patterson, Akeena Harper, Judith A. Blake
Publikováno v:
BMC Cancer, Vol 19, Iss 1, Pp 1-13 (2019)
BMC Cancer
BMC Cancer
Abstract Background Understanding mechanisms underlying specific chemotherapeutic responses in subtypes of cancer may improve identification of treatment strategies most likely to benefit particular patients. For example, triple-negative breast cance
Autor:
Rajesh M. Rao, Susan M. Mockus, Hoifung Poon, Cara Statz, Taofei Yin, Cliff Wong, Sara S. Patterson
PurposeThe explosion of molecular biomarker and treatment information in the precision medicine era drastically exacerbated difficulty in identifying patient-relevant knowledge for clinical researchers and practitioners. Curated knowledgebases, such
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::15f82413a7ecc9b4514127f19bf16416
https://doi.org/10.1101/2021.07.14.21260440
https://doi.org/10.1101/2021.07.14.21260440
Autor:
Kenji, Fujiyoshi, Elspeth A, Bruford, Pawel, Mroz, Cynthe L, Sims, Timothy J, O'Leary, Anthony W I, Lo, Neng, Chen, Nimesh R, Patel, Keyur Pravinchandra, Patel, Barbara, Seliger, Mingyang, Song, Federico A, Monzon, Alexis B, Carter, Margaret L, Gulley, Susan M, Mockus, Thuy L, Phung, Harriet, Feilotter, Heather E, Williams, Shuji, Ogino
Publikováno v:
Proc Natl Acad Sci U S A
Autor:
Elspeth A. Bruford, Federico A. Monzon, Neng Chen, Pawel Mroz, Harriet Feilotter, Mingyang Song, Shuji Ogino, Nimesh R. Patel, Margaret L. Gulley, Thuy Phung, Heather E. Williams, Susan M. Mockus, Keyur P. Patel, Anthony W.I. Lo, Timothy J. O'Leary, Alexis B. Carter, Cynthe L. Sims, Kenji Fujiyoshi, Barbara Seliger
Publikováno v:
Proceedings of the National Academy of Sciences. 118
The current lack of a standardized nomenclature system for gene products (e.g., proteins) has resulted in a haphazard counterproductive system of labeling. Different names are often used for the same gene product; the same name is sometimes used for
Autor:
Susan M. Mockus, Deborah I. Ritter, David Tamborero, Obi L. Griffith, Jeremy Goecks, Gordana Raca, Damian T. Rieke, Georgia Mayfield, Nuria Lopez-Bigas, Jianjiong Gao, Kilannin Krysiak, Melissa A. Haendel, Ryan P Duren, Olivier Elemento, Kyle Ellrott, Jordi Deu-Pons, Adam A. Margolin, Brian Walsh, Tero Aittokallio, Michael Baudis, Rodrigo Dienstmann, Subha Madhavan, Julie A. McMurry, Sara E. Patterson, Ethan Cerami, Ozman Ugur Sezerman, Robert R. Freimuth, Beth A. Pitel, Nikolaus Schultz, Lynn M. Schriml, Alex H. Wagner, Jeremy L. Warner, Mark Lawler, Jacques S. Beckmann, Dmitriy Sonkin, Catherine Del Vecchio Fitz, Xuan Shirley Li, Debyani Chakravarty, Malachi Griffith
Publikováno v:
Variant Interpretation for Cancer Consortium 2020, ' A harmonized meta-knowledgebase of clinical interpretations of somatic genomic variants in cancer ', Nature Genetics, vol. 52, no. 4, pp. 448-457 . https://doi.org/10.1038/s41588-020-0603-8
Nature Genetics
Nature genetics, vol. 52, no. 4, pp. 448-457
Scientia
Nature Genetics
Nature genetics, vol. 52, no. 4, pp. 448-457
Scientia
Precision oncology relies on accurate discovery and interpretation of genomic variants, enabling individualized diagnosis, prognosis and therapy selection. We found that six prominent somatic cancer variant knowledgebases were highly disparate in con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c37b4128ca2649aae6483eb7ae33b29f
https://pure.qub.ac.uk/en/publications/eac9e539-6ee6-4236-a0fc-64fa11bb778e
https://pure.qub.ac.uk/en/publications/eac9e539-6ee6-4236-a0fc-64fa11bb778e
Publikováno v:
Expert Review of Molecular Diagnostics. 17:549-555
Comprehensive cancer genomic profiling provides the opportunity to expose the various molecular aberrations potentially driving tumor progression. Consequently, the identity of these genetic drivers can be utilized to match a patient to the most appr
Autor:
Susan M. Mockus, Mark S. Huberman, Vanessa Spotlow, Susumu Kobayashi, Daniel B. Costa, Loren Joseph, Honey V. Reddi, Paul A. VanderLaan, Joan Malcolm, Deepa Rangachari
Publikováno v:
Lung Cancer. 106:17-21
Introduction The degree and duration of response to epidermal growth factor receptor (EGFR) inhibitors in EGFR mutated lung cancer are heterogeneous. We hypothesized that the concurrent genomic landscape of these tumors, which is currently unknown in
Autor:
Pooja Kumar, Yan Yang, Francesca Menghi, Charles Lee, Henry C. Chen, James L. Keck, Edison T. Liu, Javad Noorbakhsh, Qihui Zhu, R. Krishna Murthy Karuturi, Hyun-Soo Kim, Jeffrey H. Chuang, Mallory Ryan, Guruprasad Ananda, Chengsheng Zhang, Eliza Cerveira, Carol J. Bult, Susan M. Mockus, Joshy George
Publikováno v:
Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-16 (2018)
Scientific Reports, Vol 8, Iss 1, Pp 1-16 (2018)
The processes by which tumors evolve are essential to the efficacy of treatment, but quantitative understanding of intratumoral dynamics has been limited. Although intratumoral heterogeneity is common, quantification of evolution is difficult from cl