Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Susan M. Mitchell"'
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract The pigment cell-specific protein PMEL forms a functional amyloid matrix in melanosomes onto which the pigment melanin is deposited. The amyloid core consists of a short proteolytic fragment, which we have termed the core-amyloid fragment (C
Externí odkaz:
https://doaj.org/article/6fe1f58f16b744199acb7c25c9e073c8
Autor:
Najla Arshad, Maudry Laurent-Rolle, Wesam S Ahmed, Jack Chun-Chieh Hsu, Susan M Mitchell, Joanna Pawlak, Debrup Sengupta, Kabir H Biswas, Peter Cresswell
Publikováno v:
Proceedings of the National Academy of Sciences. 120
Major histocompatibility complex class I (MHC-I) molecules, which are dimers of a glycosylated polymorphic transmembrane heavy chain and the small protein β2-microglobulin (β2m), bind peptides in the endoplasmic reticulum that are generated by the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aff4d3a22dbe75064fcb9b075812b605
https://doi.org/10.1073/pnas.2208525120
https://doi.org/10.1073/pnas.2208525120
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
The pigment cell-specific protein PMEL forms a functional amyloid matrix in melanosomes onto which the pigment melanin is deposited. The amyloid core consists of a short proteolytic fragment, which we have termed the core-amyloid fragment (CAF) and p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b7f2448038718ed4cfd4ee038b479cf
http://europepmc.org/articles/PMC8032716
http://europepmc.org/articles/PMC8032716
Publikováno v:
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-17 (2019)
Scientific Reports, Vol 9, Iss 1, Pp 1-17 (2019)
PMEL is a pigment cell-specific protein that forms a functional amyloid matrix in melanosomes. The matrix consists of well-separated fibrillar sheets on which the pigment melanin is deposited. Using electron tomography, we demonstrate that this sheet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3c9a229ee42051af0f737756c2953d2
https://doi.org/10.1038/s41598-019-42571-6
https://doi.org/10.1038/s41598-019-42571-6
Autor:
Carolyn Seaman, Susan M. Mitchell
Publikováno v:
Information and Software Technology. 72:151-170
ContextSoftware process improvement (SPI) is one type of innovation often formulated to address problems such as uncontrollable costs, schedule overruns, and poor end product quality. This study investigates SPI through the application of knowledge m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::47a7ccda5164312f557cc27717273d2e
https://doi.org/10.1016/j.infsof.2015.12.007
https://doi.org/10.1016/j.infsof.2015.12.007
Autor:
Susan M, Mitchell, Keith N, Rand, Zheng-Zhou, Xu, Thu, Ho, Glenn S, Brown, Jason P, Ross, Peter L, Molloy
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1708
Over the last few years a number of restriction enzymes that cut DNA only if cytosines within their recognition sequences are methylated have been characterized and become commercially available. Cleavage with these enzymes to release DNA fragments i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::34c905ab0a9318d633194c0a0002c334
https://pubmed.ncbi.nlm.nih.gov/29224165
https://pubmed.ncbi.nlm.nih.gov/29224165
Autor:
Susan M. Mitchell, Jason P. Ross, Glenn S. Brown, Thu Ho, Zheng-Zhou Xu, Peter L. Molloy, Keith N. Rand
Publikováno v:
Methods in Molecular Biology ISBN: 9781493974795
Over the last few years a number of restriction enzymes that cut DNA only if cytosines within their recognition sequences are methylated have been characterized and become commercially available. Cleavage with these enzymes to release DNA fragments i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0134057965fda0e863fb24d6df469b4d
https://doi.org/10.1007/978-1-4939-7481-8_30
https://doi.org/10.1007/978-1-4939-7481-8_30
Autor:
Jason P. Ross, Melissa L. Thomas, Susan M. Mitchell, Thu Ho, Graeme P. Young, Zheng-Zhou Xu, Rohan Baker, Susanne K. Pedersen, Aidan McEvoy, Peter L. Molloy, Lloyd D. Graham, Lawrence C. LaPointe
Publikováno v:
Epigenetics
Copyright © 2014 Landes Bioscience This is an open-access article licensed under a Creative Commons Attribution 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf9839b9b81176f102a8545246f81881
http://europepmc.org/articles/PMC4164492
http://europepmc.org/articles/PMC4164492
Publikováno v:
The Journal of Immunology. 192:2480-2494
The transporter associated with antigen processing (TAP) translocates peptide antigens into the lumen of the endoplasmic reticulum (ER) for loading onto major histocompatibility complex (MHC) class I molecules. MHC class I acquires its peptide cargo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33c5887efa334c66e6cd45c301db760f
https://doi.org/10.4049/jimmunol.1302637
https://doi.org/10.4049/jimmunol.1302637
Publikováno v:
Scientific Reports
PMEL is a pigment cell protein that forms physiological amyloid in melanosomes. Many amyloids and/or their oligomeric precursors are toxic, causing or contributing to severe, incurable diseases including Alzheimer’s and prion diseases. Striking sim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1603656461af479983244df09e9805ca
https://pubmed.ncbi.nlm.nih.gov/28272432
https://pubmed.ncbi.nlm.nih.gov/28272432