Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Susan M. Kitson"'
Autor:
Moeed Akbar, Michael Mullen, W. J. Leach, Iain B. McInnes, Michael McLean, Susan M. Kitson, J. L. Campton, B. P. Rooney, Lindsay A. N. Crowe, Mark Blyth, I. D. M. Smith, Neal L. Millar, Kathryn Mccall, Simon J. Spencer
Publikováno v:
Bone & Joint Research
Objectives Tranexamic acid (TXA) is an anti-fibrinolytic medication commonly used to reduce perioperative bleeding. Increasingly, topical administration as an intra-articular injection or perioperative wash is being administered during surgery. Adult
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7c23bb480eeef64c2dd7bbe108ea1e0
https://doi.org/10.1302/2046-3758.81.bjr-2018-0181.r1
https://doi.org/10.1302/2046-3758.81.bjr-2018-0181.r1
Autor:
Moeed Akbar, Neal L. Millar, Jay Griffin, Josh Platt, Susan M. Kitson, Raquel R. Rech, Iain B. McInnes, Derek S. Gilchrist, Thomas E. Hughes, Ashlee E. Watts, Roy R. Pool
Publikováno v:
Molecular Therapy. 25:2415-2426
Tendon injuries (tendinopathies) are common in human and equine athletes and characterized by dysregulated collagen matrix, resulting in tendon damage. We have previously demonstrated a functional role for microRNA29a (miR29a) as a post-transcription
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f5c5c37fcb46b5684726b3e3f2d11ce
https://doi.org/10.1016/j.ymthe.2017.07.015
https://doi.org/10.1016/j.ymthe.2017.07.015
Autor:
George A.C. Murrell, Emma Garcia Melchor, Michael McLean, Michael Mullen, Katharina Patommel, James H. Reilly, Hai Man Cao, Iain B. McInnes, W. J. Leach, Brain P. Rooney, Susan M. Kitson, Lindsay A. N. Crowe, Simon J. Spencer, Moeed Akbar, Max Chambers, Neal L. Millar
Publikováno v:
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-12 (2019)
Scientific Reports, Vol 9, Iss 1, Pp 1-12 (2019)
Alarmins S100A8 and S100A9 are endogenous molecules released in response to environmental triggers and cellular damage. They are constitutively expressed in immune cells such as monocytes and neutrophils and their expression is upregulated under infl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad64dbe70b64796eb1d38a67de7dcaf9
https://doi.org/10.1038/s41598-018-37684-3
https://doi.org/10.1038/s41598-018-37684-3
Autor:
Neal L. Millar, Emma Garcia-Melchor, Susan M. Kitson, Derek S. Gilchrist, Stefan Siebert, I.B. McInnes, Moeed Akbar, Giacomo Cafaro
Publikováno v:
Adaptive immunity (T cells and B cells) in rheumatic diseases.
Background Although the role of IL-23/Th17 axis in psoriatic arthritis (PsA) is well known1, little data is available on the contribution of stromal cells to this pathway2. Enthesitis is a common feature of PsA and it may represent the site of onset3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0a42aaf2add7c1e9e2472ba5eb812df7
https://doi.org/10.1136/annrheumdis-2018-eular.4946
https://doi.org/10.1136/annrheumdis-2018-eular.4946
Autor:
I.B. McInnes, E. Garcia Melchor, Moeed Akbar, George A.C. Murrell, K. Patommel, Susan M. Kitson, Derek S. Gilchrist, Neal L. Millar, Lindsay A. N. Crowe
Publikováno v:
Cytokines and inflammatory mediators.
Background Alarmins- also referred to as damage associated molecular patterns (DAMPS)- are endogenous molecules mobilised in response to tissue damage known to activate the innate immune system in the early stages of disease. The molecular mechanisms
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::83bb9172c27f7ff53d16439c27071e4d
https://doi.org/10.1136/annrheumdis-2018-eular.7019
https://doi.org/10.1136/annrheumdis-2018-eular.7019
Autor:
Umberto G. Fazzi, Susan M. Kitson, Lindsay A. N. Crowe, Moeed Akbar, George A.C. Murrell, Shauna C Kerr, Emma Garcia-Melchor, Jonathon Z B Cher, Michael McLean, Neal L. Millar, Stephen C Hannah
Publikováno v:
The American journal of sports medicine. 46(3)
Background: The pathophysiological mechanisms behind proliferation of fibroblasts and deposition of dense collagen matrix in idiopathic frozen shoulder remain unclear. Alarmins (also known as danger signals) are endogenous molecules that are released
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08cfda8bc0b7398c42b480535886ddfa
https://pubmed.ncbi.nlm.nih.gov/29190116
https://pubmed.ncbi.nlm.nih.gov/29190116
Publikováno v:
Methods. 55:287-292
The activities of many mammalian membrane proteins including G-protein coupled receptors are cholesterol-dependent. Unlike higher eukaryotes, yeast do not make cholesterol. Rather they make a related molecule called ergosterol. As cholesterol and erg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4e74a1701206ac5bbc3e139ec00953e
https://doi.org/10.1016/j.ymeth.2011.09.023
https://doi.org/10.1016/j.ymeth.2011.09.023
Autor:
Ammad, Ahmed, Ivana, Hollan, Samuel A, Curran, Susan M, Kitson, Marcello P, Riggio, Knut, Mikkelsen, Sven M, Almdahl, Pål, Aukrust, Iain B, McInnes, Carl S, Goodyear
Publikováno v:
Arthritis & Rheumatology (Hoboken, N.j.)
Objective Patients with rheumatoid arthritis (RA) are at increased risk of developing cardiovascular disease (CVD) via mechanisms that have not yet been defined. Inflammatory pathways, in particular within the vascular adventitia, are implicated in t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::12ea53dc1f12f10d14b03fc2d86d1a4e
https://pubmed.ncbi.nlm.nih.gov/26749303
https://pubmed.ncbi.nlm.nih.gov/26749303
Publikováno v:
Veterinary Dermatology. 7:59-66
The temporal patterns of dermal immune cell influx were compared in mice and sheep, species reputedly resistant and susceptible, respectively, to infection with Dermatophilus congolensis. In both species, the response involved early mast cell degranu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2937f46f2fe6f466c451a0d969f6f901
https://doi.org/10.1111/j.1365-3164.1996.tb00228.x
https://doi.org/10.1111/j.1365-3164.1996.tb00228.x
Autor:
Susan M. Kitson, Carl S. Goodyear, Lindsay M. Maclellan, Robert J. B. Nibbs, Fujimi Sugiyama, Stephen A. Beers, Katja Thümmler, Jennifer Montgomery, Iain B. McInnes, Gregg J. Silverman
Publikováno v:
Arthritis and rheumatism. 63(12)
Objective Cells of the monocytic lineage play fundamental roles in the regulation of health, ranging from the initiation and resolution of inflammation to bone homeostasis. In rheumatoid arthritis (RA), the inflamed synovium exhibits characteristic i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fd5c7aa680eb791be9e381a0668ba00
https://pubmed.ncbi.nlm.nih.gov/22127707
https://pubmed.ncbi.nlm.nih.gov/22127707