Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Susan M. Dougherty"'
Publikováno v:
Cells, Vol 10, Iss 7, p 1679 (2021)
Tyrosine kinase inhibitors (TKIs) targeting the kinase domain of the epidermal growth factor receptor (EGFR), such as erlotinib, have dramatically improved clinical outcomes of patients with EGFR-driven non-small cell lung carcinomas (NSCLCs). Howeve
Externí odkaz:
https://doaj.org/article/4965fb7a8acf4f9baf9b6f4ce0194193
This reader-friendly text examines the key foundational studies in early literacy. It addresses such essential questions as how research informs current practices and where the field still needs to go to provide the best learning opportunities for al
Autor:
Carolyn M. Klinge, Chunyuan Chen, Albert R. Cunningham, Yoannis Imbert-Fernandez, Susan M. Dougherty, Susan M. Isaacs, Margarita M. Ivanova, Nalinie S. Wickramasinghe, David J. Schultz
Supplementary Data from Anacardic Acid Inhibits Estrogen Receptor α–DNA Binding and Reduces Target Gene Transcription and Breast Cancer Cell Proliferation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7df0d8f6820a16c27ee6784988154a33
https://doi.org/10.1158/1535-7163.22485890.v1
https://doi.org/10.1158/1535-7163.22485890.v1
Autor:
Carolyn M. Klinge, Chunyuan Chen, Albert R. Cunningham, Yoannis Imbert-Fernandez, Susan M. Dougherty, Susan M. Isaacs, Margarita M. Ivanova, Nalinie S. Wickramasinghe, David J. Schultz
Anacardic acid (AnAc; 2-hydroxy-6-alkylbenzoic acid) is a dietary and medicinal phytochemical with established anticancer activity in cell and animal models. The mechanisms by which AnAc inhibits cancer cell proliferation remain undefined. AnAc 24:1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0773c400dd2b86f183017cc21ba5bb4c
https://doi.org/10.1158/1535-7163.c.6532127.v1
https://doi.org/10.1158/1535-7163.c.6532127.v1
Autor:
Brian F. Clem, James L. Wittliff, Susan M. Dougherty, Carolyn M. Klinge, Traci Kruer, Benjamin Green, Stephanie Metcalf, Belinda J Petri
Publikováno v:
Endocr Relat Cancer
Estrogen receptor-positive breast cancer (ER+ BC) is the most common form of breast carcinoma accounting for approximately 70% of all diagnoses. Although ER-targeted therapies have improved survival outcomes for this BC subtype, a significant proport
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd421a662e396a39eb95a5afa7ff7b28
https://doi.org/10.1530/erc-19-0510
https://doi.org/10.1530/erc-19-0510
Autor:
Traci L Kruer, Susan M Dougherty, Lindsey Reynolds, Elizabeth Long, Tanya de Silva, William W Lockwood, Brian F Clem
Publikováno v:
PLoS ONE, Vol 11, Iss 11, p e0166363 (2016)
Maternally expressed gene 3 (MEG3, mouse homolog Gtl2) encodes a long noncoding RNA (lncRNA) that is expressed in many normal tissues, but is suppressed in various cancer cell lines and tumors, suggesting it plays a functional role as a tumor suppres
Externí odkaz:
https://doaj.org/article/a44577db6b824411b7ab42afeb607155
Autor:
Nadiia Lypova, Lilibeth Lanceta, Susan M. Dougherty, Jason A. Chesney, Yoannis Imbert-Fernandez
Publikováno v:
Cancer Research. 82:1772-1772
Breast cancer driven by estrogen receptor (ER) is responsible for approximately 60-70% of cases among women. Selective inhibition of cyclin-dependent kinases 4 and 6 (CDK4/6) and ER signaling is now standard-of-care therapy for ER positive (ER+) meta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e0c02fa22b43f6742f7fc0502d6a80e3
https://doi.org/10.1158/1538-7445.am2022-1772
https://doi.org/10.1158/1538-7445.am2022-1772
Autor:
Megan Webster, Emily Deegan, Katelyn Shortt, Susan M. Dougherty, Lynn Stothers, Dena R Howland, Kuan-Yin N Chen, Margot S. Damaser, Jay Ethridge, Basile Tessier-Cloutier, Leslie C. Sherwood, April N. Herrity, Max Boakye, Femke Streijger, Kyoung-Tae Kim, Martin Keung, Kitty So, Charlotte J. Morrison, Sevda C. Aslan, Seth Tigchelaar, Charles H. Hubscher, Elena B. Okon, Shera Fisk, Alex Kavanagh, Brian K. Kwon, Neda Manouchehri
Publikováno v:
Journal of neurotrauma. 38(9)
There is an increasing need to develop approaches that will not only improve the clinical management of neurogenic lower urinary tract dysfunction (NLUTD) after spinal cord injury (SCI), but also advance therapeutic interventions aimed at recovering
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05c502994f8a10c6001dbd13dc7e0440
https://pubmed.ncbi.nlm.nih.gov/33499736
https://pubmed.ncbi.nlm.nih.gov/33499736
Autor:
Daniel W. Wilkey, James Bradley, John O. Trent, Michael L. Merchant, Traci Kruer, Brian F. Clem, Rumeysa Biyik-Sit, Susan M. Dougherty
Publikováno v:
Cancers
Volume 13
Issue 16
Cancers, Vol 13, Iss 3938, p 3938 (2021)
Volume 13
Issue 16
Cancers, Vol 13, Iss 3938, p 3938 (2021)
Simple Summary Alternative functions for metabolic proteins have recently been shown to drive cancer growth. These may include differential enzymatic activity or novel protein associations. Phosphoserine aminotransferase 1 (PSAT1) participates in cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ded4c5600da22412670faf0c9fe1ae6
https://doi.org/10.3390/cancers13163938
https://doi.org/10.3390/cancers13163938
Autor:
Rumeysa Biyik-Sit, Traci Kruer, Brian F. Clem, Stephanie Metcalf, Nazarul Hasan, Susan M. Dougherty, Lindsey Reynolds
Publikováno v:
Clinicalexperimental metastasis. 37(1)
Breast cancer is the second leading cause of cancer-related deaths among women and 90% of these mortalities can be attributed to progression to metastatic disease. In particular, triple negative breast cancer (TNBC) is extremely aggressive and freque
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea23af09f91b0386f1d763882024767b
https://pubmed.ncbi.nlm.nih.gov/31630284
https://pubmed.ncbi.nlm.nih.gov/31630284