Zobrazeno 1 - 10
of 197
pro vyhledávání: '"Susan M. Carlton"'
Autor:
Allison Doyle Brackley, Ruben Gomez, Kristi A. Guerrero, Armen N. Akopian, Marc J. Glucksman, Junhui Du, Susan M. Carlton, Nathaniel A. Jeske
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-17 (2017)
Abstract Mechanical pain serves as a base clinical symptom for many of the world’s most debilitating syndromes. Ion channels expressed by peripheral sensory neurons largely contribute to mechanical hypersensitivity. Transient Receptor Potential A 1
Externí odkaz:
https://doaj.org/article/78d62c56f9cc4d618d2eefe60eaa2041
Autor:
Junhui Du, Yan Zuo, Lin Li, Edgar T. Walters, Zizhen Wu, Susan M. Carlton, Jeffrey A. Frost, Fuhua Xie, Qing Yang
Publikováno v:
Journal of Neurotrauma. 34:1260-1270
A majority of people who have sustained spinal cord injury (SCI) experience chronic pain after injury, and this pain is highly resistant to available treatments. Contusive SCI in rats at T10 results in hyperexcitability of primary sensory neurons, wh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80a92402d9ea7c8e6459ae201807547c
https://doi.org/10.1089/neu.2016.4789
https://doi.org/10.1089/neu.2016.4789
Publikováno v:
Neuroscience. 334:134-147
Several lines of evidence indicate group III metabotropic glutamate receptors (mGluRs) have systemic anti-hyperalgesic effects. We hypothesized this could occur through modulation of TRP channels on nociceptors. This study used a multifaceted approac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f72a9fd1a73687e5d7d0a8b37efb7f03
https://doi.org/10.1016/j.neuroscience.2016.07.047
https://doi.org/10.1016/j.neuroscience.2016.07.047
Autor:
Junhui Du, Matthew P. Rowan, Ruben Gomez, Nathaniel A. Jeske, Kalina Szteyn, Susan M. Carlton
Publikováno v:
Pain. 156:2364-2372
Glutamate serves as the primary excitatory neurotransmitter in the nervous system. Previous studies have identified a role for glutamate and group I metabotropic receptors as targets for study in peripheral inflammatory pain. However, the coordinatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8620578897283d62f3412d217ddfc5ab
https://doi.org/10.1097/j.pain.0000000000000295
https://doi.org/10.1097/j.pain.0000000000000295
Autor:
Junhui Du, Kristi A. Guerrero, Armen N. Akopian, Ruben Gomez, Nathaniel A. Jeske, Susan M. Carlton, Marc J. Glucksman, Allison Doyle Brackley
Publikováno v:
Scientific Reports
Scientific Reports, Vol 7, Iss 1, Pp 1-17 (2017)
Scientific Reports, Vol 7, Iss 1, Pp 1-17 (2017)
Mechanical pain serves as a base clinical symptom for many of the world’s most debilitating syndromes. Ion channels expressed by peripheral sensory neurons largely contribute to mechanical hypersensitivity. Transient Receptor Potential A 1 (TRPA1)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::532c24881de32007eff0a66093dba8c7
https://doi.org/10.1038/s41598-017-01999-4
https://doi.org/10.1038/s41598-017-01999-4
Autor:
George R. Jackson, Mathieu F. Bakhoum, Gerald A. Campbell, Christine Y. Bakhoum, Susan M. Carlton, Zhixia Ding
Publikováno v:
Translational Research. 164:1-12
Autophagy is essential to neuronal homeostasis, and its impairment is implicated in the development of neurodegenerative pathology. However, the underlying mechanisms and consequences of this phenomenon remain a matter of conjecture. We show that mis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6f1678541eb100e15b6aab3e9567b9f
https://doi.org/10.1016/j.trsl.2014.01.016
https://doi.org/10.1016/j.trsl.2014.01.016
Autor:
Susan M. Carlton
Publikováno v:
The Journal of Physiology. 592:3403-3411
Nociceptive primary afferents have three surprising properties: they are highly complex in their expression of neurotransmitters and receptors and most probably participate in autocrine and paracrine interactions; they are capable of exerting tonic a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8511140ff5a3d064126e07394322cef8
https://doi.org/10.1113/jphysiol.2013.269654
https://doi.org/10.1113/jphysiol.2013.269654
Autor:
Monique R. Ferguson, Joshua G. Lisinicchia, Shao Jun Tang, Yuqiang Shi, Alai Tan, Benjamin B. Gelman, Su Bo Yuan, Xiangfu Zhou, Guangyu Li, Jinghong Chen, Susan M. Carlton, Sushil K. Sarna
Publikováno v:
Annals of Neurology. 75:837-850
Objective Chronic pain is a common neurological comorbidity of human immunodeficiency virus (HIV)-1 infection, but the etiological cause remains elusive. The objective of this study was to identify the HIV-1 causal factor that critically contributes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5c76f06aec2d33c0bcf22c4862ad6d42
https://doi.org/10.1002/ana.24139
https://doi.org/10.1002/ana.24139
Publikováno v:
Current Neuropharmacology
Chronic pain affects billions of lives globally and is a major public health problem in the United States. However, pain management is still a challenging task due to a lack of understanding of the fundamental mechanisms of pain. In the past decades
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8cda96d8397a077a93bf7781b092d99
https://doi.org/10.2174/1570159x113119990040
https://doi.org/10.2174/1570159x113119990040
Autor:
Shentai Zhou, Richard B. Clark, Junhui Du, Shijin Yin, Guangwei Du, Susan M. Carlton, Weihua Yu, Aihua Qian, Qing Yang, Jialie Luo, Edgar T. Walters, Hongzhen Hu
Publikováno v:
Journal of Clinical Investigation. 123:3941-3951
Retinoids are structurally related derivatives of vitamin A and are required for normal vision as well as cell proliferation and differentiation. Clinically, retinoids are effective in treating many skin disorders and cancers. Application of retinoid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf5b5c66a5548996b990aae226a123f8
https://doi.org/10.1172/jci66413
https://doi.org/10.1172/jci66413