Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Susan M Siew"'
Autor:
Konstantin Knoblich, Sara Cruz Migoni, Susan M Siew, Elizabeth Jinks, Baksho Kaul, Hannah C Jeffery, Alfie T Baker, Muath Suliman, Katerina Vrzalikova, Hisham Mehenna, Paul G Murray, Francesca Barone, Ye H Oo, Philip N Newsome, Gideon Hirschfield, Deirdre Kelly, Steven P Lee, Biju Parekkadan, Shannon J Turley, Anne L Fletcher
Publikováno v:
PLoS Biology, Vol 16, Iss 9, p e2005046 (2018)
The microenvironment of lymphoid organs can aid healthy immune function through provision of both structural and molecular support. In mice, fibroblastic reticular cells (FRCs) create an essential T-cell support structure within lymph nodes, while hu
Externí odkaz:
https://doaj.org/article/cfdd586171da4f0abe7ee7e056ab364c
Autor:
Helen M. Evans, Susan M Siew
Publikováno v:
Journal of Paediatrics and Child Health. 56:1760-1768
Neonatal liver disease encompasses many diagnoses, including structural and genetic aetiologies. Many have significant health implications requiring long-term specialist treatment including liver transplantation. Jaundice is a common presenting featu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c166be588387ed31c7c2781a56824765
https://doi.org/10.1111/jpc.15064
https://doi.org/10.1111/jpc.15064
Autor:
Szun S. Tay, Ian E. Alexander, Elena Venuti, Susan M. Siew, Erhua Zhu, Christine Bolitho, Sharon C. Cunningham
Publikováno v:
Hepatology (Baltimore, Md.)References. 70(6)
Recombinant adeno-associated viral (rAAV) vectors are highly promising vehicles for liver-targeted gene transfer, with therapeutic efficacy demonstrated in preclinical models and clinical trials. Progressive familial intrahepatic cholestasis type 3 (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5840e09c6ddfbc3d2fd963aa4420d67b
https://pubmed.ncbi.nlm.nih.gov/31099022
https://pubmed.ncbi.nlm.nih.gov/31099022
Autor:
Elizabeth Jinks, Deirdre Kelly, Hisham Mehenna, Philip N. Newsome, Katerina Vrzalikova, Gideon M. Hirschfield, Baksho Kaul, Alfie T. Baker, Sara Cruz Migoni, Ye Htun Oo, Francesca Barone, Steven P. Lee, Susan M. Siew, Hannah C. Jeffery, Anne L. Fletcher, Biju Parekkadan, Shannon J. Turley, Konstantin Knoblich, Paul Murray, Muath Suliman
Publikováno v:
PLoS Biology, Vol 16, Iss 9, p e2005046 (2018)
The microenvironment of lymphoid organs can aid healthy immune function through provision of both structural and molecular support. In mice, fibroblastic reticular cells (FRCs) create an essential T-cell support structure within lymph nodes, while hu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2a712d96f93e8dba61914ff6a8bd44f
https://doaj.org/article/cfdd586171da4f0abe7ee7e056ab364c
https://doaj.org/article/cfdd586171da4f0abe7ee7e056ab364c
Autor:
Susan M. Siew, Deirdre Kelly
Publikováno v:
Sherlock's Diseases of the Liver and Biliary System
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1e80687f6ff3a8b658cb5d7fc6e7e84a
https://doi.org/10.1002/9781119237662.ch31
https://doi.org/10.1002/9781119237662.ch31
Autor:
Allison P Dane, Cindy Kok, Philip W. Kuchel, Sharon C. Cunningham, Kevin Carpenter, Grant J Logan, Ian E. Alexander, Susan M. Siew
Publikováno v:
Molecular Therapy. 21:1823-1831
Viral vectors based on adeno-associated virus (AAV) are showing exciting promise in gene therapy trials targeting the adult liver. A major challenge in extending this promise to the pediatric liver is the loss of episomal vector genomes that accompan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b6cbc76b35760589755e92a41fabb70
https://doi.org/10.1038/mt.2013.139
https://doi.org/10.1038/mt.2013.139
Autor:
Andras Nagy, Susan M. Siew, Natsuki Sasaki, Gagan Garg, Ian E. Alexander, Claus V. Hallwirth, Nicola A. Hetherington, Iacovos P. Michael, Gustavo de Alencastro, Christine Bolitho, Sharon C. Cunningham
Publikováno v:
Molecular Therapy. 23
Liver-targeted gene therapy using adeno-associated virus-based vectors (rAAV) shows therapeutic promise in animal models and adult-focused clinical trials. This promise, however, is not directly translatable to the growing liver where rapid clearance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39c0e6707449892c2f6abc037d289715
Autor:
Claus V. Hallwirth, Kevin Carpenter, Andras Nagy, Natsuki Sasaki, Iacovos P. Michael, Sharon C. Cunningham, Nicola A. Hetherington, Christine Bolitho, Ian E. Alexander, Gustavo de Alencastro, Susan M. Siew, Gagan Garg
Publikováno v:
Hepatology (Baltimore, Md.). 62(2)
Liver-targeted gene therapy based on recombinant adeno-associated viral vectors (rAAV) shows promising therapeutic efficacy in animal models and adult-focused clinical trials. This promise, however, is not directly translatable to the growing liver,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1de004a017e668c0a07683f4e8bdc5b6
https://pubmed.ncbi.nlm.nih.gov/26011400
https://pubmed.ncbi.nlm.nih.gov/26011400