Zobrazeno 1 - 10
of 81
pro vyhledávání: '"Susan M Parkhurst"'
Autor:
Mitsutoshi Nakamura, Jeffrey M Verboon, Tessa E Allen, Maria Teresa Abreu-Blanco, Raymond Liu, Andrew N M Dominguez, Jeffrey J Delrow, Susan M Parkhurst
Publikováno v:
PLoS Genetics, Vol 16, Iss 12, p e1009186 (2020)
Cells are exposed to frequent mechanical and/or chemical stressors that can compromise the integrity of the plasma membrane and underlying cortical cytoskeleton. The molecular mechanisms driving the immediate repair response launched to restore the c
Externí odkaz:
https://doaj.org/article/2c807706b195430a899ca85a63cc725d
Publikováno v:
Cell Reports, Vol 43, Iss 5, Pp 114215- (2024)
Summary: Cells have robust wound repair systems to prevent further damage or infection and to quickly restore cell cortex integrity when exposed to mechanical and chemical stress. Actomyosin ring formation and contraction at the wound edge are major
Externí odkaz:
https://doaj.org/article/79a0c2285ace4c078dd267fff0298745
Autor:
Elena V Linardopoulou, Sean S Parghi, Cynthia Friedman, Gregory E Osborn, Susan M Parkhurst, Barbara J Trask
Publikováno v:
PLoS Genetics, Vol 3, Iss 12, p e237 (2007)
Subtelomeres are duplication-rich, structurally variable regions of the human genome situated just proximal of telomeres. We report here that the most terminally located human subtelomeric genes encode a previously unrecognized third subclass of the
Externí odkaz:
https://doaj.org/article/aabc5285b1f84d54aab6db1a45e4785e
Autor:
Daniella Bianchi-Frias, Amir Orian, Jeffrey J Delrow, Julio Vazquez, Alicia E Rosales-Nieves, Susan M Parkhurst
Publikováno v:
PLoS Biology, Vol 2, Iss 7, p E178 (2004)
Members of the widely conserved Hairy/Enhancer of split family of basic Helix-Loop-Helix repressors are essential for proper Drosophila and vertebrate development and are misregulated in many cancers. While a major step forward in understanding the m
Externí odkaz:
https://doaj.org/article/289383a2d4934df3a033da25bc424da0
Publikováno v:
Journal of Cell Biology. 222
Nuclear envelope (NE) budding is a nuclear pore–independent nuclear export pathway, analogous to the egress of herpesviruses, and required for protein quality control, synapse development, and mitochondrial integrity. The physical formation of NE b
Publikováno v:
Scientific Reports. 13
Rho family GTPases regulate both linear and branched actin dynamics by activating downstream effectors to facilitate the assembly and function of complex cellular structures such as lamellipodia and contractile actomyosin rings. Wiskott-Aldrich Syndr
Publikováno v:
Faculty Reviews. 12
Coordinated efforts of different actin filament populations are needed for optimal cell wound repair
Publikováno v:
Molecular biology of the cell.
Cells are subjected to a barrage of daily insults that often lead to their cortex being ripped open and requiring immediate repair. An important component of the cell's repair response is the formation of an actomyosin ring at the wound periphery to
Nuclear envelope (NE) budding is a nuclear pore independent nuclear export pathway, analogous to the egress of herpesviruses, and required for protein quality control, synapse development and mitochondrial integrity. The physical formation of NE buds
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::373202c0b394fb2855ff9145944960a6
https://doi.org/10.1101/2022.11.16.516846
https://doi.org/10.1101/2022.11.16.516846
Autor:
Alan B. Cantor, Inga Hofmann, Vijay G. Sankaran, David A. Williams, Dilnar Mahmut, Mitsutoshi Nakamura, Amy E. Geddis, Nour J. Abdulhay, Susan M. Parkhurst, Jeffrey M. Verboon, Becky Manes, Haydar Frangoul, Stacey Gabriel, Ah Ram Kim, Genevieve M. Crane, Daryl E. Klein, Thomas E. Akie, Namrata Gupta, Meghan E. Kapp, Satish K. Nandakumar
Publikováno v:
Journal of Clinical Immunology
Studies of genetic blood disorders have advanced our understanding of the intrinsic regulation of hematopoiesis. However, such genetic studies have only yielded limited insights into how interactions between hematopoietic cells and their microenviron