Zobrazeno 1 - 10
of 308
pro vyhledávání: '"Susan M Gasser"'
Autor:
Marta Rodríguez-Martínez, Jens Nielsen, Sam Dupont, Jessica Vamathevan, Beverley J Glover, Lindsey C Crosswell, Brendan Rouse, Ben F Luisi, Chris Bowler, Susan M Gasser, Detlev Arendt, Tobias J Erb, Victor de Lorenzo, Edith Heard, Kiran Raosaheb Patil
Publikováno v:
PLoS Biology, Vol 20, Iss 4, p e3001623 (2022)
Molecular biology holds a vast potential for tackling climate change and biodiversity loss. Yet, it is largely absent from the current strategies. We call for a community-wide action to bring molecular biology to the forefront of climate change solut
Externí odkaz:
https://doaj.org/article/0b8e5d7d368e410b8ab8d90ed9606b57
Publikováno v:
PLoS Genetics, Vol 15, Iss 1, p e1007851 (2019)
Sister chromatid cohesion on chromosome arms is essential for the segregation of homologous chromosomes during meiosis I while it is dispensable for sister chromatid separation during mitosis. It was assumed that, unlike the situation in mitosis, chr
Externí odkaz:
https://doaj.org/article/845d14a941c945ee88a9fa414a802679
Publikováno v:
EMBO Molecular Medicine, Vol 6, Iss 8, Pp 995-1002 (2014)
Abstract The inhibition of the central growth regulatory kinase TOR, which participates in two complexes, TORC1 and TORC2, has been a focus of metabolic and cancer studies for many years. Most studies have dealt with TORC1, the canonical target of ra
Externí odkaz:
https://doaj.org/article/aaf5a081ffe64d938fdd102a6651464a
Autor:
Daichi Iwasaki, Kayoko Hayashihara, Hiroki Shima, Mika Higashide, Masahiro Terasawa, Susan M Gasser, Miki Shinohara
Publikováno v:
PLoS Genetics, Vol 12, Iss 3, p e1005942 (2016)
Because DNA double-strand breaks (DSBs) are one of the most cytotoxic DNA lesions and often cause genomic instability, precise repair of DSBs is vital for the maintenance of genomic stability. Xrs2/Nbs1 is a multi-functional regulatory subunit of the
Externí odkaz:
https://doaj.org/article/1d3eafe200024e5b84f5a933489297b4
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e81015 (2013)
The conserved family of RecQ DNA helicases consists of caretaker tumour suppressors, that defend genome integrity by acting on several pathways of DNA repair that maintain genome stability. In budding yeast, Sgs1 is the sole RecQ helicase and it has
Externí odkaz:
https://doaj.org/article/24244bfd88c740b29af8477d13cd7efe
Autor:
Stephanie Kueng, Monika Tsai-Pflugfelder, Mariano Oppikofer, Helder C Ferreira, Emma Roberts, Chinyen Tsai, Tim-Christoph Roloff, Ragna Sack, Susan M Gasser
Publikováno v:
PLoS Genetics, Vol 8, Iss 5, p e1002727 (2012)
Silent information regulator proteins Sir2, Sir3, and Sir4 form a heterotrimeric complex that represses transcription at subtelomeric regions and homothallic mating type (HM) loci in budding yeast. We have performed a detailed biochemical and genetic
Externí odkaz:
https://doaj.org/article/1e487314e4eb44cd9def661e7328d350
Autor:
Takahito Yoshida, Kenji Shimada, Yukako Oma, Véronique Kalck, Kazumi Akimura, Angela Taddei, Hitoshi Iwahashi, Kazuto Kugou, Kunihiro Ohta, Susan M Gasser, Masahiko Harata
Publikováno v:
PLoS Genetics, Vol 6, Iss 4, p e1000910 (2010)
Actin-related proteins are ubiquitous components of chromatin remodelers and are conserved from yeast to man. We have examined the role of the budding yeast actin-related protein Arp6 in gene expression, both as a component of the SWR1 complex (SWR-C
Externí odkaz:
https://doaj.org/article/f489620134124f3bb346050c0ff28317
Publikováno v:
Nature Reviews Molecular Cell Biology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0858bd4968d0c49f67be7d327d2df96f
https://doi.org/10.1038/s41580-023-00599-7
https://doi.org/10.1038/s41580-023-00599-7
Publikováno v:
Nature Reviews Molecular Cell Biology
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05fa1b38838ae60cba6d58f395064236
https://doi.org/10.1038/s41580-022-00483-w
https://doi.org/10.1038/s41580-022-00483-w
Autor:
Peter Zeller, Helge Großhans, Hubertus Kohler, Susan M. Gasser, Stephen P. Methot, Alexander van Oudenaarden, Jan Padeken, Dimos Gaidatzis, Colin Delaney, Giovanna Brancati
Publikováno v:
Nature Cell Biology, 23
Nature Cell Biology, 23(11), 1163-1175. Nature Publishing Group
Nature Cell Biology
Nature Cell Biology, 23(11), 1163-1175. Nature Publishing Group
Nature Cell Biology
The developmental role of histone H3K9 methylation (H3K9me), which typifies heterochromatin, remains unclear. In Caenorhabditis elegans, loss of H3K9me leads to a highly divergent upregulation of genes with tissue and developmental-stage specificity.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43ad7303513d2c1364ef7d9198ef80e9
https://doi.org/10.1038/s41556-021-00776-w
https://doi.org/10.1038/s41556-021-00776-w