Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Susan M Fetherston"'
Autor:
Peter Boyd, Delphine Desjardins, Sandeep Kumar, Susan M Fetherston, Roger Le-Grand, Nathalie Dereuddre-Bosquet, Berglind Helgadóttir, Ásgeir Bjarnason, Manjula Narasimhan, R Karl Malcolm
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0125682 (2015)
Product adherence is a pivotal issue in the development of effective vaginal microbicides to reduce sexual transmission of HIV. To date, the six Phase III studies of vaginal gel products have relied primarily on self-reporting of adherence. Accurate
Externí odkaz:
https://doaj.org/article/6267f1e9aa484458a3d37ec70a5f5fed
Autor:
Susan M. Fetherston, R. Karl Malcolm
Publikováno v:
Contraception. 88:321-325
Multipurpose prevention technologies (MPTs) have the potential to address global reproductive and sexual health issues such as unintended pregnancy and STIs including HIV HPV herpes simplex virus and syphilis. MPTs are products that are intentionally
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9b5260b895188ed1fc149acabad783c
https://doi.org/10.1016/j.contraception.2013.06.009
https://doi.org/10.1016/j.contraception.2013.06.009
Autor:
Ian Major, Brid Devlin, Andrew Brimer, Clare McCoy, Jonathon D. S. Holt, Diarmaid J. Murphy, Susan M. Fetherston, R. Karl Malcolm, Sandeep Kumar, Wendy Blanda, Peter Boyd
Publikováno v:
Boyd, P, Fetherston, S M, McCoy, C F, Major, I, Murphy, D J, Kumar, S, Holt, J, Brimer, A, Blanda, W, Devlin, B & Malcolm, R K 2016, ' Matrix and reservoir-type multipurpose vaginal rings for controlled release of dapivirine and levonorgestrel ', International Journal of Pharmaceutics, vol. 511, no. 1, pp. 619-629 . https://doi.org/10.1016/j.ijpharm.2016.07.051
A matrix-type silicone elastomer vaginal ring providing 28-day continuous release of dapivirine (DPV) ⿿ a lead candidate human immunodeficiency virus type 1 (HIV-1) microbicide compound ⿿ has recently demonstrated moderate levels of protection in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5724c1be40fb5bf0655cdf956fd3122f
https://pure.qub.ac.uk/en/publications/matrix-and-reservoirtype-multipurpose-vaginal-rings-for-controlled-release-of-dapivirine-and-levonorgestrel(1c672efb-3a3e-40dc-bd55-f59c37050f55).html
https://pure.qub.ac.uk/en/publications/matrix-and-reservoirtype-multipurpose-vaginal-rings-for-controlled-release-of-dapivirine-and-levonorgestrel(1c672efb-3a3e-40dc-bd55-f59c37050f55).html
Publikováno v:
International Journal of Women's Health
Malcolm, R K, Fetherston, S M, McCoy, C F, Boyd, P & Major, I 2012, ' Vaginal rings for delivery of HIV microbicides ', International Journal of Women's Health, vol. 2012, no. 4, pp. 595-605 . https://doi.org/10.2147/IJWH.S36282
Malcolm, R K, Fetherston, S M, McCoy, C F, Boyd, P & Major, I 2012, ' Vaginal rings for delivery of HIV microbicides ', International Journal of Women's Health, vol. 2012, no. 4, pp. 595-605 . https://doi.org/10.2147/IJWH.S36282
Following the successful development of long-acting steroid-releasing vaginal ring devices for treatment of menopausal symptoms and contraception, there is now considerable interest in applying similar devices to the controlled release of microbicide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7aa068351772fec0c8dbe2bedca739f3
http://europepmc.org/articles/PMC3508658
http://europepmc.org/articles/PMC3508658
Autor:
Jaime Moscoso, James M. Smith, Priya Srinivasan, Deborah Lowry, Sara E. Butler, Susan M. Fetherston, Karl Malcolm
Publikováno v:
Journal of Medical Primatology. 40:249-285
Background: Heterosexual HIV transmission continues to spread worldwide. Intravaginal rings (IVRs) formulated with antiretroviral drugs hold great promise for HIV prevention in women. IVRs provide the benefit of being coitally-independent and coitall
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2f9f931b483afbc4605fcc018faa8a3c
https://doi.org/10.1111/j.1600-0684.2011.00491.x
https://doi.org/10.1111/j.1600-0684.2011.00491.x
Autor:
Susan M. Fetherston, Clare McCoy, Karen-Leigh Edwards, Peter Boyd, R. Karl Malcolm, Marcella McBride, Stephen Ampofo
Publikováno v:
Fetherston, S M, Boyd, P, McCoy, C F, McBride, M C, Edwards, K-L, Ampofo, S & Malcolm, R K 2013, ' A silicone elastomer vaginal ring for HIV prevention containing two microbicides with different mechanisms of action ' European Journal of Pharmaceutical Sciences, vol 48, no. 3, pp. 406-415 . DOI: 10.1016/j.ejps.2012.12.002
Vaginal rings are currently being developed for the long-term (at least 30 days) continuous delivery of microbicides against human immunodeficiency virus (HIV). Research to date has mostly focused on devices containing a single antiretroviral compoun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc401a621a43dfc0bd9930c8215387be
https://pubmed.ncbi.nlm.nih.gov/23266465
https://pubmed.ncbi.nlm.nih.gov/23266465
Publikováno v:
Therapeutic delivery. 1(6)
Background: Over half of all HIV-infected adults are women and heterosexual intercourse is a significant mode of viral transmission. This review examines the potential for using polymeric vaginal ring systems to provide controlled delivery of HIV mic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2c113204da4590673a408603a04f3fa
https://pubmed.ncbi.nlm.nih.gov/22834014
https://pubmed.ncbi.nlm.nih.gov/22834014
Sustained Release of the CCR5 Inhibitors CMPD167 and Maraviroc from Vaginal Rings in Rhesus Macaques
Autor:
Deborah Lowry, Peter Boyd, Kelsi K. Rasmussen, Ronald S. Veazey, Diarmaid J. Murphy, Ian Major, Laura A. Doyle, Laurie Goldman, Leslie Geer, John P. Moore, Robin J. Shattock, Per Johan Klasse, Thomas J. Ketas, Susan M. Fetherston, R. Karl Malcolm
Antiretroviral entry inhibitors are now being considered as vaginally administered microbicide candidates for the prevention of the sexual transmission of human immunodeficiency virus. Previous studies testing the entry inhibitors maraviroc and CMPD1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acbc1bde5197688d1168ae571b4c34d8
https://europepmc.org/articles/PMC3346641/
https://europepmc.org/articles/PMC3346641/
Autor:
Delphine Desjardins, R. Karl Malcolm, Sandeep Kumar, Berglind Helgadóttir, Nathalie Dereuddre-Bosquet, Susan M. Fetherston, Roger LeGrand, Peter Boyd, Ásgeir Bjarnason, Manjulaa Narasimhan
Publikováno v:
Boyd, P, Desjardins, D, Kumar, S, Fetherston, S M, Le-Grand, R, Dereuddre-Bosquet, N, Helgadottir, B, Bjarnason, A, Narasimhan, M & Malcolm, R K 2015, ' A Temperature-Monitoring Vaginal Ring for Measuring Adherence ', PLoS ONE, vol. 10, no. 5, e0125682 . https://doi.org/10.1371/journal.pone.0125682
PLoS ONE, Vol 10, Iss 5, p e0125682 (2015)
PLoS ONE
PLoS ONE, Vol 10, Iss 5, p e0125682 (2015)
PLoS ONE
BackgroundProduct adherence is a pivotal issue in the development of effective vaginal microbicides to reduce sexual transmission of HIV. To date, the six Phase III studies of vaginal gel products have relied primarily on self-reporting of adherence.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::342028ba8bbc7abebce6b32b4e77ff3b
https://doi.org/10.1371/journal.pone.0125682
https://doi.org/10.1371/journal.pone.0125682
Autor:
Clare McCoy, Chris Gimour, Jonathon D. S. Holt, Jeremy Nuttall, Diarmaid J. Murphy, Wendy Blanda, Ian Major, Andrew Brimer, Tiffany Derrick, Brid Devlin, Peter Boyd, Karl Malcolm, Susan M. Fetherston
Publikováno v:
AIDS Research and Human Retroviruses. 30:A68-A68
Background: By extending the use duration of vaginal rings (VRs) the overall production cost per patient per month can be greatly reduced. Matrix-type ring designs produce an initial burst of drug release and concentrations during the burst must be m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0121146545e42ddf55b4b6e671121671
https://doi.org/10.1089/aid.2014.5124.abstract
https://doi.org/10.1089/aid.2014.5124.abstract