Zobrazeno 1 - 10
of 81
pro vyhledávání: '"Susan M, Parkhurst"'
Publikováno v:
Cell Reports, Vol 43, Iss 5, Pp 114215- (2024)
Summary: Cells have robust wound repair systems to prevent further damage or infection and to quickly restore cell cortex integrity when exposed to mechanical and chemical stress. Actomyosin ring formation and contraction at the wound edge are major
Externí odkaz:
https://doaj.org/article/79a0c2285ace4c078dd267fff0298745
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract Rho family GTPases regulate both linear and branched actin dynamics by activating downstream effectors to facilitate the assembly and function of complex cellular structures such as lamellipodia and contractile actomyosin rings. Wiskott-Aldr
Externí odkaz:
https://doaj.org/article/46f00131308f422fba93dfad3db10dfa
Publikováno v:
Cells, Vol 12, Iss 11, p 1532 (2023)
In the original publication [...]
Externí odkaz:
https://doaj.org/article/93f23d5d6abc4495830c7928fbca07c1
Autor:
Anthony O. Beas, Patricia B. Gordon, Clara L. Prentiss, Carissa Perez Olsen, Matthew A. Kukurugya, Bryson D. Bennett, Susan M. Parkhurst, Daniel E. Gottschling
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
Age-associated metabolic changes include lipid accumulation. Here, the authors show that with replicative aging yeast accumulate lipid droplets which protect cells from cold stress and can be modulated through Biosynthesis of NAD+ 2 (BNA2).
Externí odkaz:
https://doaj.org/article/ccc42411f0664158949caf4ea685050d
Publikováno v:
Cells, Vol 11, Iss 18, p 2777 (2022)
To cope with continuous physiological and environmental stresses, cells of all sizes require an effective wound repair process to seal breaches to their cortex. Once a wound is recognized, the cell must rapidly plug the injury site, reorganize the cy
Externí odkaz:
https://doaj.org/article/4e285a509a1c4b60b8259652addf05c6
Autor:
Mitsutoshi Nakamura, Jeffrey M Verboon, Tessa E Allen, Maria Teresa Abreu-Blanco, Raymond Liu, Andrew N M Dominguez, Jeffrey J Delrow, Susan M Parkhurst
Publikováno v:
PLoS Genetics, Vol 16, Iss 12, p e1009186 (2020)
Cells are exposed to frequent mechanical and/or chemical stressors that can compromise the integrity of the plasma membrane and underlying cortical cytoskeleton. The molecular mechanisms driving the immediate repair response launched to restore the c
Externí odkaz:
https://doaj.org/article/2c807706b195430a899ca85a63cc725d
Publikováno v:
Journal of Cell Biology. 222
Nuclear envelope (NE) budding is a nuclear pore–independent nuclear export pathway, analogous to the egress of herpesviruses, and required for protein quality control, synapse development, and mitochondrial integrity. The physical formation of NE b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::301e17ea720dd2bcd5fddfc296574f88
https://doi.org/10.1083/jcb.202211074
https://doi.org/10.1083/jcb.202211074
Publikováno v:
Faculty Reviews. 12
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::914d8c383c5fb200fe90f58910fe2a67
https://doi.org/10.12703/r/12-7
https://doi.org/10.12703/r/12-7
Coordinated efforts of different actin filament populations are needed for optimal cell wound repair
Publikováno v:
Molecular biology of the cell.
Cells are subjected to a barrage of daily insults that often lead to their cortex being ripped open and requiring immediate repair. An important component of the cell's repair response is the formation of an actomyosin ring at the wound periphery to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f142248d53c84b0ecd333df62281d38
https://pubmed.ncbi.nlm.nih.gov/36598808
https://pubmed.ncbi.nlm.nih.gov/36598808
Autor:
Mitsutoshi Nakamura, Andrew N. M. Dominguez, Jacob R. Decker, Alexander J. Hull, Jeffrey M. Verboon, Susan M. Parkhurst
Publikováno v:
Open Biology, Vol 8, Iss 10 (2018)
Repair of wounds to individual cells is crucial for organisms to survive daily physiological or environmental stresses, as well as pathogen assaults, which disrupt the plasma membrane. Sensing wounds, resealing membranes, closing wounds and remodelli
Externí odkaz:
https://doaj.org/article/0ba800e14a22450bbd564c2207ee0d99