Zobrazeno 1 - 10
of 117
pro vyhledávání: '"Susan M, Harrington"'
Autor:
Tina J. Hieken, Garth D. Nelson, Thomas J. Flotte, Eric P. Grewal, Jun Chen, Robert R. McWilliams, Lisa A. Kottschade, Lu Yang, Evidio Domingo-Musibay, Roxana S. Dronca, Yiyi Yan, Svetomir N. Markovic, Anastasios Dimou, Heather N. Montane, Courtney L. Erskine, Mara A. Piltin, Daniel L. Price, Samir S. Khariwala, Jane Hui, Carrie A. Strand, Susan M. Harrington, Vera J. Suman, Haidong Dong, Matthew S. Block
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract Both targeted therapies and immunotherapies provide benefit in resected Stage III melanoma. We hypothesized that the combination of targeted and immunotherapy given prior to therapeutic lymph node dissection (TLND) would be tolerable and dri
Externí odkaz:
https://doaj.org/article/6734662876464a8cb916380502e32069
Autor:
Whitney Barham, Michelle Hsu, Xin Liu, Susan M. Harrington, Jacob B. Hirdler, Joanina K. Gicobi, Xingxing Zhu, Hu Zeng, Kevin D. Pavelko, Yiyi Yan, Aaron S. Mansfield, Haidong Dong
Publikováno v:
ImmunoHorizons. 7:125-139
Seven different anti–PD-1 and PD-L1 mAbs are now widely used in the United States to treat a variety of cancer types, but no clinical trials have compared them directly. Furthermore, because many of these Abs do not cross-react between mouse and hu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::615e457446924fa37ecabcda70272396
https://doi.org/10.4049/immunohorizons.2200054
https://doi.org/10.4049/immunohorizons.2200054
Autor:
Haidong Dong, Svetomir N Markovic, Aaron S Mansfield, Jacob J Orme, Elizabeth Ann L Enninga, Fabrice Lucien-Matteoni, Heather Dale, Edwin Burgstaler, Susan M Harrington, Matthew K Ball, Sean S Park, Mathew S Block, Yiyi Yan, Roxana S Dronca, Jeffrey L Winters
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 2 (2020)
Background Trans-acting programmed death-ligand 1 (PD-L1) derives from malignant cells in three known forms. High levels of secreted splice variant PD-L1 (sPD-L1), ADAM10/ADAM17-shed sPD-L1, and PD-L1-positive extracellular vesicles (evPD-L1) each pr
Externí odkaz:
https://doaj.org/article/12cda94bbdc0496a8a76193abb6aa4f3
Autor:
Xiaosheng Wu, Yanli Li, Xin Liu, Chunhua Chen, Susan M. Harrington, Siyu Cao, Tiancheng Xie, Tu Pham, Aaron S. Mansfield, Yiyi Yan, Eugene D. Kwon, Liewei Wang, Kun Ling, Haidong Dong
Publikováno v:
Heliyon, Vol 5, Iss 3, Pp e01309- (2019)
Externí odkaz:
https://doaj.org/article/b9d5013a4fb94e94b8365246538943d0
Autor:
Zesheng An, Michelle A. Hsu, Joanina K. Gicobi, Tianxiao Xu, Susan M. Harrington, Henan Zhang, Kevin D. Pavelko, Jacob B. Hirdler, Christine M. Lohse, Reza Nabavizadeh, Rodrigo R. Pessoa, Vidit Sharma, R. Houston Thompson, Bradley C. Leibovich, Haidong Dong, Fabrice Lucien
Publikováno v:
The Journal of Immunology.
The intrinsic and acquired resistance to PD-1/PD-L1 immune checkpoint blockade is an important challenge for patients and clinicians because no reliable tool has been developed to predict individualized response to immunotherapy. In this study, we de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::abb4da63a0825cb4b371f87e603284dc
https://doi.org/10.4049/jimmunol.2200933
https://doi.org/10.4049/jimmunol.2200933
Autor:
Haidong Dong, Daniel D. Billadeau, George Vasmatzis, Minetta C. Liu, Hong Qin, Jie Sun, Sean S. Park, Svetomir N. Markovic, Yiyi Yan, Aaron S. Mansfield, Roxana S. Dronca, Ruifeng Guo, Xiaosheng Wu, Susan M. Harrington, Zesheng An, Dileep D. Monie, Cristina Correia, Hu Li, Roxane R. Lavoie, Fabrice Lucien, Kodi E. Peterson Martinez, Hyoungjun Ham, Xin Liu, Jacob B. Hirdler, Joanina K. Gicobi, Henan Zhang, Ying Li, Whitney Barham, Ti Wen
Supplementary Data from NKG7 Is a T-cell–Intrinsic Therapeutic Target for Improving Antitumor Cytotoxicity and Cancer Immunotherapy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59e9ed652eeef9f654fca88546c3c20d
https://doi.org/10.1158/2326-6066.22544529.v1
https://doi.org/10.1158/2326-6066.22544529.v1
Autor:
Haidong Dong, Daniel D. Billadeau, George Vasmatzis, Minetta C. Liu, Hong Qin, Jie Sun, Sean S. Park, Svetomir N. Markovic, Yiyi Yan, Aaron S. Mansfield, Roxana S. Dronca, Ruifeng Guo, Xiaosheng Wu, Susan M. Harrington, Zesheng An, Dileep D. Monie, Cristina Correia, Hu Li, Roxane R. Lavoie, Fabrice Lucien, Kodi E. Peterson Martinez, Hyoungjun Ham, Xin Liu, Jacob B. Hirdler, Joanina K. Gicobi, Henan Zhang, Ying Li, Whitney Barham, Ti Wen
Cytotoxic CD8+ T cells (CTL) are a crucial component of the immune system notable for their ability to eliminate rapidly proliferating malignant cells. However, the T-cell intrinsic factors required for human CTLs to accomplish highly efficient antit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04fea2893f953bb6feb4e64b7e4c86ce
https://doi.org/10.1158/2326-6066.c.6550677
https://doi.org/10.1158/2326-6066.c.6550677
Autor:
Haidong Dong, Daniel D. Billadeau, George Vasmatzis, Minetta C. Liu, Hong Qin, Jie Sun, Sean S. Park, Svetomir N. Markovic, Yiyi Yan, Aaron S. Mansfield, Roxana S. Dronca, Ruifeng Guo, Xiaosheng Wu, Susan M. Harrington, Zesheng An, Dileep D. Monie, Cristina Correia, Hu Li, Roxane R. Lavoie, Fabrice Lucien, Kodi E. Peterson Martinez, Hyoungjun Ham, Xin Liu, Jacob B. Hirdler, Joanina K. Gicobi, Henan Zhang, Ying Li, Whitney Barham, Ti Wen
Supplementary Figure from NKG7 Is a T-cell–Intrinsic Therapeutic Target for Improving Antitumor Cytotoxicity and Cancer Immunotherapy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::133a0ae566ca33430811c0d90b29d21f
https://doi.org/10.1158/2326-6066.22544526
https://doi.org/10.1158/2326-6066.22544526
Autor:
Eugene D. Kwon, Kenneth R. Olivier, Keith M. Furutani, Aaron S. Mansfield, Michael P. Grams, Christopher J. Krco, Susan M. Harrington, Xin Liu, Haidong Dong, Sean S. Park
Supplemental Figure 1. Synergistic effects of PD-1 and CTLA-4 blockade in enhancing antitumor abscopal effects.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e124339b14dccf8d0f69f5e06feed70e
https://doi.org/10.1158/2326-6066.22538773.v1
https://doi.org/10.1158/2326-6066.22538773.v1
Autor:
Eugene D. Kwon, Kenneth R. Olivier, Keith M. Furutani, Aaron S. Mansfield, Michael P. Grams, Christopher J. Krco, Susan M. Harrington, Xin Liu, Haidong Dong, Sean S. Park
We investigated the influence of PD-1 expression on the systemic antitumor response (abscopal effect) induced by stereotactic ablative radiotherapy (SABR) in preclinical melanoma and renal cell carcinoma models. We compared the SABR-induced antitumor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d6ae7ca4e37bdc7b6716d42e6ddcc60
https://doi.org/10.1158/2326-6066.c.6548887.v1
https://doi.org/10.1158/2326-6066.c.6548887.v1