Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Susan Leed"'
Autor:
Katrien Van Bocxlaer, Diana Caridha, Chad Black, Brian Vesely, Susan Leed, Richard J. Sciotti, Gert-Jan Wijnant, Vanessa Yardley, Stéphanie Braillard, Charles E. Mowbray, Jean-Robert Ioset, Simon L. Croft
Publikováno v:
International Journal for Parasitology: Drugs and Drug Resistance, Vol 11, Iss , Pp 129-138 (2019)
Objectives: Drugs for Neglected Diseases initiative (DNDi) has identified three chemical lead series, the nitroimidazoles, benzoxaboroles and aminopyrazoles, as innovative treatments for visceral leishmaniasis. The leads discovered using phenotypic s
Externí odkaz:
https://doaj.org/article/85d89c5c5d1b46e5bb81f2a521136ced
Autor:
Diana Caridha, Mark Hickman, Lisa Xie, Franklyn Ngundam, Erin Milner, Amanda Schenk, Kirk Butler, Dylan Nugent, Patricia Lee, Norma Roncal, Susan Leed, Eve Hosford, Jangwoo Lee, Richard J. Sciotti, Gregory Reichard, Chad Black, Mara Kreishman-Deitrick, Qigui Li, Brian Vesely
Publikováno v:
Malaria Journal, Vol 18, Iss 1, Pp 1-15 (2019)
Abstract Background Rodent malaria models are extensively used to predict treatment outcomes in human infections. There is a constant need to improve and refine these models by innovating ways to apply new scientific findings and cutting edge technol
Externí odkaz:
https://doaj.org/article/b2caeece80d94ce2ab66bc1e98c7f17b
Autor:
Anny Fortin, Diana P Caridha, Susan Leed, Franklyn Ngundam, Jenell Sena, Tom Bosschaerts, Sandi Parriott, Mark R Hickman, Thomas H Hudson, Max Grogl
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 8, Iss 9, p e3144 (2014)
Cutaneous leishmaniasis (CL) represents a range of skin diseases caused by infection with Leishmania parasites and associated with tissue inflammation and skin ulceration. CL is clinically widespread in both the Old and New World but lacks treatments
Externí odkaz:
https://doaj.org/article/19b4a5713b574cbb908851985c685931
Autor:
Diana, Caridha, Richard J, Sciotti, Jason, Sousa, Brian, Vesely, Tesfaye, Teshome, Gustave, Bonkoungou, Chau, Vuong, Susan, Leed, Mozna, Khraiwesh, Erica, Penn, Mara, Kreishman-Deitrick, Patricia, Lee, Brandon, Pybus, John S, Lazo, Elizabeth R, Sharlow
Publikováno v:
ACS infectious diseases. 7(2)
Cutaneous leishmaniasis (CL) is the most common form of leishmaniasis affecting human populations, yet CL remains largely ignored in drug discovery programs. CL causes disfiguring skin lesions and often relapses after "clinical cure" using existing t
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2081
Confirming the in vivo efficacy of potential antileishmanial compounds that display in vitro potency and good chemical characteristics is one of the most important steps in preclinical research drug discovery before human clinical trials begin. Here
Autor:
Diana, Caridha, Sandi, Parriot, Thomas H, Hudson, Thierry, Lang, Franklyn, Ngundam, Susan, Leed, Jenell, Sena, Michael, Harris, Michael, O'Neil, Richard, Sciotti, Lisa, Read, Herve, Lecoeur, Mark, Hickman, Max, Grogl
Publikováno v:
Antimicrobial Agents and Chemotherapy
In any drug discovery and development effort, a reduction in the time of the lead optimization cycle is critical to decrease the time to license and reduce costs. In addition, ethical guidelines call for the more ethical use of animals to minimize th
Publikováno v:
New Genetics and Society, Vol 41, Iss 3, Pp 254-283 (2022)
Genomic Tumour Testing (GTT) is an emerging site of “experimental care” in oncology [Cambrosio, Alberto, Peter Keating, Etienne Vignola-Gagné, Sylvain Besle, and Pascale Bourret. 2018a. “Extending Experimentation: Oncology’s Fading Boundary
Externí odkaz:
https://doaj.org/article/e090d77ff0c4490eb91a78ff1921a8f8