Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Susan Larrabee"'
Autor:
Daniel A. Solomon, Susan Larrabee, Joshua Ellis, Parsa Erfani, Shawn F. Johnson, Katherine M. Rich, Raquel Sofia Sandoval, Nora Y. Osman
Publikováno v:
BMC Medical Education, Vol 22, Iss 1, Pp 1-6 (2022)
Abstract Background The Coronavirus disease 2019 (Covid-19) pandemic caused an abrupt disruption in clinical care and medical education, putting patients at increased risk for social stressors and displacing medical students from traditional clerkshi
Externí odkaz:
https://doaj.org/article/7e681c8d5ec94d5ebe2002e6bc5f19ea
Publikováno v:
Open Forum Infectious Diseases
Background Motivational interviewing (MI) may have a positive impact on antiretroviral therapy (ART) adherence. However, few studies focus on non-adherent patients at high risk of viral transmission, as identified by unsuppressed viral load. Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b79f365cfda99bf296a6cb628c2c92fb
http://europepmc.org/articles/PMC6253521
http://europepmc.org/articles/PMC6253521
Autor:
Vincent Leveque, Gloria Ao-Ieong, Sophie Le Pogam, Bamberg Joe Timothy, Javier de Vicente, Stengel Peter J, Stacey Renee Spencer, John P. Fischer, Todd R. Elworthy, Andrew J. Briggs, Jim Li, Peter Mohr, Michael Brandl, Sunil Sukhtankar, Ramona Hilgenkamp, Calvin Yee, Ludmila Alexandrova, Robinson John E, Fell Jay Bradford, Beihan Wang, April Wong, Robert Than Hendricks, Farrell Robert P, Isabel Najera, David Bernard Smith, Seth F. Harris, Sonal Rajyaguru, Susan Larrabee, James F. Blake, George Adjabeng
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 19:5652-5656
A series of benzo[d]isothiazole-1,1-dioxides were designed and evaluated as inhibitors of HCV polymerase NS5B. Structure-based design led to the incorporation of a high affinity methyl sulfonamide group. Structure-activity relationship (SAR) studies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::270693e52369b485d5d38536330a0ea0
https://doi.org/10.1016/j.bmcl.2009.08.022
https://doi.org/10.1016/j.bmcl.2009.08.022
Autor:
Ludmila Alexandrova, Connie Oshiro, Ramona Hilgenkamp, Stengel Peter J, Isabel Najera, Peter Mohr, Jahari Laurant Tracy, Susan Larrabee, James F. Blake, David Bernard Smith, Bamberg Joe Timothy, George Adjabeng, Vincent Leveque, Andrew J. Briggs, Brian Xu, Seth F. Harris, Rebecca A. Stephenson, Sonal Rajyaguru, Manjiri Ghate, Beihan Wang, John P. Fischer, Stacey Renee Spencer, Calvin Yee, Sophie Le Pogam, Elbert Chin, Michael Brandl, Fell Jay Bradford, Gloria Ao-Ieong, Sunil Sukhtankar, Robert Than Hendricks, Jim Li, Robinson John E, Todd R. Elworthy, Farrell Robert P, Javier de Vicente
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 19:3642-3646
A new series of benzothiazine-substituted quinolinediones were evaluated as inhibitors of HCV polymerase NS5B. SAR studies on this series revealed a methyl sulfonamide group as a high affinity feature. Analogues with this group showed submicromolar p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af0673cb666121215e5519a1cfe7e1c9
https://doi.org/10.1016/j.bmcl.2009.05.004
https://doi.org/10.1016/j.bmcl.2009.05.004
Autor:
David Bernard Smith, George Hill, Tony Tran, Carla Washington, Zhongjiang Jia, Micaela B. Reddy, Lei Hong, Michael Brandl, Keshab Sarma, Susan Larrabee, Xu Hadig, Xiaoyang Wu, Raj Birudaraj, Marites Holper, Tom Alfredson
Publikováno v:
Drug Development and Industrial Pharmacy. 34:683-691
The nucleoside analog R1479 is a potent and highly selective inhibitor of NS5b-directed hepatitis C virus (HCV) RNA polymerase in vitro. Because of its limited permeability, lipophilic prodrugs of R1479 were screened. Selection of the prodrug involve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c556e7c7f74f74d8b3a1c023d8d209a
https://doi.org/10.1080/03639040701836636
https://doi.org/10.1080/03639040701836636
Publikováno v:
Journal of separation science. 30(5)
Two stationary phases attached to a silica hydride surface, cholesterol and bidentate C18, are investigated with a number of pharmaceutically related compounds in order to illustrate the various retention mechanisms that are possible for these bonded
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23e990c0c4cbab37796050ac5ffd20d1
https://pubmed.ncbi.nlm.nih.gov/17461101
https://pubmed.ncbi.nlm.nih.gov/17461101
Autor:
Welch Teresa Rosanne, David Michael Goldstein, Stacie A. Dalrymple, Joann La Fargue, Jay Bertrand, Chakk Ramesha, Michelle F. Browner, Will Tao, Sheila Zipfel, Eva Papp, Alejandra Trejo, Kelly Young, Jose Freire-Moar, James Dunn, Susan Larrabee, Rick Roberts, Mary Welch, Daniel Mcweeney, Armando Villasenor, Jean Marc Lapierre, David Rotstein, On-Yee So, Sharada S. Labadie, Phyllis E. Whiteley, Ken Clifford, Bong San Pablo, Tom Alfredson, Seth Harris, Paul Weller, Eric B. Sjogren, Fujun Li, Francisco X. Mountain View Talamas
Publikováno v:
Journal of medicinal chemistry. 49(5)
A novel class of highly selective inhibitors of p38 MAP kinase was discovered from high throughput screening. The synthesis and optimization of a series of 5-amino-N-phenyl-1H-pyrazol-4-yl-3-phenylmethanones is described. An X-ray crystal structure o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74021732dae7f5fb513dc237543e3952
https://pubmed.ncbi.nlm.nih.gov/16509574
https://pubmed.ncbi.nlm.nih.gov/16509574
Publikováno v:
AIDS clinical care. 15(3)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2944a9400fd1ce93bd4bbb821498c289
https://pubmed.ncbi.nlm.nih.gov/12685418
https://pubmed.ncbi.nlm.nih.gov/12685418