Zobrazeno 1 - 10
of 254
pro vyhledávání: '"Susan L. Thibeault"'
Autor:
Vlasta Lungova, Madhu Gowda, Jessica M. Fernandez, Stephanie Bartley, Anumitha Venkatraman, Federico E. Rey, Susan L. Thibeault
Publikováno v:
Disease Models & Mechanisms, Vol 17, Iss 7 (2024)
Externí odkaz:
https://doaj.org/article/5ebf42e3763f4d29aed399e7d9a8fbdf
Publikováno v:
iScience, Vol 27, Iss 6, Pp 110156- (2024)
Summary: Microbiota play a critical role in the development and training of host innate and adaptive immunity. We present the cellular landscape of the upper airway, specifically the larynx, by establishing a reference single-cell atlas, while dissec
Externí odkaz:
https://doaj.org/article/499cd083e6fe4a98b3faec41ae07b541
Publikováno v:
PLoS ONE, Vol 19, Iss 7 (2024)
Externí odkaz:
https://doaj.org/article/59b0d60843c5437381a9fa1858109f7a
Publikováno v:
PLoS ONE, Vol 19, Iss 5 (2024)
Externí odkaz:
https://doaj.org/article/8f7a7350b7544c3695f0327c6372c65c
Publikováno v:
Laryngoscope Investigative Otolaryngology, Vol 7, Iss 6, Pp 1963-1972 (2022)
Abstract Objective The primary aim of this study was to identify expression of TRPV3 and TRPV4 chemoreceptors across perinatal and adult stages using a murine model with direct comparisons to human laryngeal mucosa. Our secondary aim was to establish
Externí odkaz:
https://doaj.org/article/05546be536164828b5be9ccaab2e366b
Publikováno v:
Laryngoscope Investigative Otolaryngology, Vol 7, Iss 2, Pp 444-453 (2022)
Abstract Objectives The epithelial associated mucus layer of vocal fold (VF) mucosa, plays an essential role in protecting and lubricating the tissue, as well as promoting normal voice quality. Serving as a habitat for laryngeal microbiota involved i
Externí odkaz:
https://doaj.org/article/40be6608874e4eb782e6494798de171f
Publikováno v:
Disease Models & Mechanisms, Vol 15, Iss 8 (2022)
Vaping has been reported to cause acute epiglottitis, a life-threatening airway obstruction induced by direct epithelial injury and subsequent inflammatory reaction. Here, we show that we were able to recapitulate this phenomenon in vitro. Exposure o
Externí odkaz:
https://doaj.org/article/6cb9482fe63a4e3cbe661f773602e57f
Autor:
Kristy D. Wendt, Jared Brown, Vlasta Lungova, Vidisha Mohad, Christina Kendziorski, Susan L. Thibeault
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
The larynx, trachea, and esophagus share origin and proximity during embryonic development. Clinical and experimental evidence support the existence of neurophysiological, structural, and functional interdependencies before birth. This investigation
Externí odkaz:
https://doaj.org/article/f47179dbf4ea443cb43d3bdcd605824b
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
There is a lack of human models to study vocal fold epithelia making it difficult to provide therapies for vocal fold disease. Here, the authors generate a human-based model of vocal fold mucosa that mimics in utero development and shows inflammation
Externí odkaz:
https://doaj.org/article/34aff485983d44beb8daab94f4462674
Publikováno v:
BMC Genomics, Vol 20, Iss 1, Pp 1-19 (2019)
Abstract Background Physical forces, such as mechanical stress, are essential for tissue homeostasis and influence gene expression of cells. In particular, the fibroblast has demonstrated sensitivity to extracellular matrices with assumed adaptation
Externí odkaz:
https://doaj.org/article/bd3596cf81994dd8a728b5567f07b1fc