Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Susan L. Semple-Rowland"'
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 13 (2019)
Primary cilia are microtubule-based organelles that are typically present on cells during the G0 or G1-S/G2 phases of the cell cycle. Recent studies of glioblastoma (GBM) biopsies, a brain tumor that is notorious for its aggressive growth and resista
Externí odkaz:
https://doaj.org/article/876184e16ddf4cd3861ca68770b57d7b
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e51385 (2012)
We previously demonstrated that aged ovariectomized rats that had received prior estradiol treatment in middle-age exhibited increased levels of estrogen receptor alpha (ERα) in the hippocampus as well as enhanced hippocampal dependent memory as com
Externí odkaz:
https://doaj.org/article/7e37e43b28834987a60586a40c041007
Autor:
eMalick G Njie, Svetlana Kantorovich, Garrett W Astary, Cameron Green, Tong Zheng, Susan L Semple-Rowland, Dennis A Steindler, Malisa Sarntinoranont, Wolfgang J Streit, David R Borchelt
Publikováno v:
PLoS ONE, Vol 7, Iss 4, p e34097 (2012)
Transplantation of neural stems cells (NSCs) could be a useful means to deliver biologic therapeutics for late-stage Alzheimer's disease (AD). In this study, we conducted a small preclinical investigation of whether NSCs could be modified to express
Externí odkaz:
https://doaj.org/article/3be446a067114b12aa8ea6bd71e187fa
Autor:
Jonathan D Verrier, Irina Madorsky, William E Coggin, Mero Geesey, Michael Hochman, Elleanor Walling, Daniel Daroszewski, Kristofer S Eccles, Rachel Ludlow, Susan L Semple-Rowland
Publikováno v:
PLoS ONE, Vol 6, Iss 5, p e20553 (2011)
The disease processes underlying inherited retinal disease are complex and are not completely understood. Many of the corrective gene therapies designed to treat diseases linked to mutations in genes specifically expressed in photoreceptor cells rest
Externí odkaz:
https://doaj.org/article/61545cf1e97247dba6c46820b34a538a
Autor:
Melissa L Williams, Jason E Coleman, Shannon E Haire, Tomas S Aleman, Artur V Cideciyan, Izabel Sokal, Krzysztof Palczewski, Samuel G Jacobson, Susan L Semple-Rowland
Publikováno v:
PLoS Medicine, Vol 3, Iss 6, p e201 (2006)
BackgroundLeber congenital amaurosis (LCA) is a genetically heterogeneous group of retinal diseases that cause congenital blindness in infants and children. Mutations in the GUCY2D gene that encodes retinal guanylate cyclase-1 (retGC1) were the first
Externí odkaz:
https://doaj.org/article/8d84b8df1c384746aff1d60ac92cb9b9
Autor:
Matthew R. Sarkisian, Megan M. Le, George Ugartemendia, Lan Hoang-Minh, Tyler S. Smith, Alexander K. Parker, Jason E. Coleman, Eric W. Atkinson, Susan L. Semple-Rowland
Publikováno v:
Experimental Neurology. 282:119-127
Neonatal or early-life seizures (ELS) are often associated with life-long neurophysiological, cognitive and behavioral deficits, but the underlying mechanisms contributing to these deficits remain poorly understood. Newborn, post-migratory cortical n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87e0ae3140c9ffc9c113174efcd869cd
https://doi.org/10.1016/j.expneurol.2016.05.015
https://doi.org/10.1016/j.expneurol.2016.05.015
Autor:
Gabriel De Leon, Matthew R. Sarkisian, George Ugartemendia, Benjamin Griffith, Susan L. Semple-Rowland, Brent A. Reynolds, Loic P. Deleyrolle, Duane Mitchell, Hunter S. Futch, Dorit Siebzehnrubl, Lan Hoang-Minh, Joshua J. Breunig
Publikováno v:
Oncotarget, vol 7, iss 6
Oncotarget
Oncotarget
// Lan B. Hoang-Minh 1, 3 , Loic P. Deleyrolle 2, 3 , Dorit Siebzehnrubl 1 , George Ugartemendia 1 , Hunter Futch 2 , Benjamin Griffith 2 , Joshua J. Breunig 5- 9 , Gabriel De Leon 2, 4 , Duane A. Mitchell 2, 3, 4 , Susan Semple-Rowland 1 , Brent A.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60f66abb5fa502d47cc82298a6d7768c
https://doi.org/10.18632/oncotarget.6854
https://doi.org/10.18632/oncotarget.6854
Publikováno v:
Methods. 66:466-473
The abilities of lentiviral vectors to carry large transgenes (~ 8Kb) and to efficiently infect and integrate these genes into the genomes of both dividing and non-dividing cells make them ideal candidates for transport of genetic material into cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::278496e8b066e98477081add8b17edd9
https://doi.org/10.1016/j.ymeth.2013.06.026
https://doi.org/10.1016/j.ymeth.2013.06.026
Autor:
Kristina K. Aenlle, Thomas C. Foster, Asha Rani, Xiaoxia Han, Ashok Kumar, Linda A. Bean, Susan L. Semple-Rowland
Publikováno v:
The Journal of Neuroscience. 33:2671-2683
The expression of the ERα and ERβ estrogen receptors in the hippocampus may be important in the etiology of age-related cognitive decline. To examine the role of ERα and ERβ in regulating transcription and learning, ovariectomized wild-type (WT)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e76bc9d4bff50e7592e560165a6d076f
https://doi.org/10.1523/jneurosci.4937-12.2013
https://doi.org/10.1523/jneurosci.4937-12.2013
Autor:
Ashton Sequeira, Ronald J. Mandel, Ashok V. Kumar, Matthew R. Sarkisian, Gileno F. Filho, Thomas C. Foster, Susan L. Semple-Rowland, Sarah M. Guadiana, Alexander K. Parker, Gerry Shaw
Publikováno v:
Frontiers in Aging Neuroscience
Frontiers in Aging Neuroscience, Vol 8 (2016)
Frontiers in Aging Neuroscience, Vol 8 (2016)
The primary cilia of forebrain neurons assemble around birth and become enriched with neuromodulatory receptors. Our understanding of the permanence of these structures and their associated signaling pathways in the aging brain is poor, but they are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e857ba89543d9615535b8796c678b33f