Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Susan L. Pichla-Gollon"'
Autor:
Marcio O. Lasaro, Nia Tatsis, Hildegund C. J. Ertl, Shih-Wen Lin, Mark Drinker, Guangping Gao, Susan L. Pichla-Gollon, Scott E. Hensley, Larissa Herkenhoff-Haut, James M. Wilson, Jeffrey M. Bergelson
Publikováno v:
Journal of virology. 83(11)
A major obstacle to the use of adenovirus vectors derived from common human serotypes, such as human adenovirus 5 (AdHu5), is the high prevalence of virus-neutralizing antibodies in the human population. We previously constructed a variant of chimpan
Autor:
Hildegund C. J. Ertl, Xiangyang Zhou, Feng Xue, James M. Wilson, Guangping Gao, Susan L. Pichla-Gollon, Roger M. Burnett, John J. Rux, Jeffrey M. Bergelson, Mark Drinker
Publikováno v:
Journal of virology. 81(4)
Virus-specific neutralizing antibodies present an obstacle to the effective use of adenovirus vectors for gene therapy and vaccination. The specific sites recognized by neutralizing antibodies have not been identified for any adenovirus, but they hav