Výsledky vyhledávání - "Susan L. Patterson"

An improved treatment planning and quality assurance process for Collaborative Ocular Melanoma Study eye plaque brachytherapy

Autor: Robert A. Weersink, Heather Ballantyne, A. Di Tomasso, Jette Borg, Alexandra Rink, Susan L. Patterson, Alex Vitkin, Akbar Beiki-Ardakani

Publikováno v: Brachytherapy. 18:658-667

Purpose To develop a treatment planning platform for episcleral Collaborative Ocular Melanoma Study plaque therapy in an established treatment planning software and to improve an existing quality assurance (QA) process for nonuniformly loaded plaques

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca903fb4843fcc2d51dce2629c9ced7a
https://doi.org/10.1016/j.brachy.2019.05.008

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Use of hydrogel spacer for improved rectal dose-sparing in patients undergoing radical radiotherapy for localized prostate cancer: First Canadian experience

Autor: Susan L. Patterson, A. Sundaramurthy, Peter Chung, Joelle Helou, Anne Di Tomasso, Alejandro Berlin, Heather Ballantyne, Andrew Bayley, Tony Lam

Publikováno v: Canadian Urological Association Journal. 11:373-5

We describe the initial experience using a hydrogel spacer (SpaceOAR) to separate the prostate-rectum interspace in patients planned to undergo radical hypofractionated image-guided intensity-modulated radiotherapy (IG-IMRT). We depict and discuss th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25c26e484ef5cf5e5f495db7c1f00032
https://doi.org/10.5489/cuaj.4681

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Immune dysregulation and cognitive vulnerability in the aging brain: Interactions of microglia, IL-1β, BDNF and synaptic plasticity

Autor: Susan L. Patterson

Publikováno v: Neuropharmacology. 96:11-18

Older individuals often experience declines in cognitive function after events (e.g. infection, or injury) that trigger activation of the immune system. This occurs at least in part because aging sensitizes the response of microglia (the brain's resi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cfbfc5a3a20254ddf4a193c2992917b
https://doi.org/10.1016/j.neuropharm.2014.12.020

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High Dose Rate Brachytherapy as a Treatment Option in Endobronchial Tumors

Autor: Alexandra Rink, Andrea Bezjak, Kasia Czarnecka, Susan L. Patterson, Andrew McPartlin, Ali Hosni, Elantholiparameswaran Saibishkumar

Publikováno v: Lung Cancer International

Purpose. To report our experience with high dose rate endobronchial brachytherapy (HDR-EBBT) and to assess its efficacy and tolerability with possibility of its use in selected cases with curative intent.Method. Retrospective review of patients with

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b265f53b3defee136fdb38ad44eeb1d
http://europepmc.org/articles/PMC4963588

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Little Exercise, Big Effects: Reversing Aging and Infection-Induced Memory Deficits, and Underlying Processes

Autor: Heidi E.W. Day, Steven F. Maier, Matthew G. Frank, Nicole Y. Crysdale, Ruth M. Barrientos, Timothy R. Chapman, Serge Campeau, Susan L. Patterson, Linda R. Watkins, Jared T. Ahrendsen

Publikováno v: The Journal of Neuroscience. 31:11578-11586

We have previously found that healthy aged rats are more likely to suffer profound memory impairments following a severe bacterial infection than are younger adult rats. Such a peripheral challenge is capable of producing a neuroinflammatory response

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e79e1067c158752d57db4ecf2e5abcfb
https://doi.org/10.1523/jneurosci.2266-11.2011

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Aging and a Peripheral Immune Challenge Interact to Reduce Mature Brain-Derived Neurotrophic Factor and Activation of TrkB, PLCγ1, and ERK in Hippocampal Synaptoneurosomes

Autor: Ruth M. Barrientos, Susan L. Patterson, Giuseppe P. Cortese, Steven F. Maier

Publikováno v: The Journal of Neuroscience. 31:4274-4279

For reasons that are not well understood, aging significantly increases brain vulnerability to challenging life events. High-functioning older individuals often experience significant cognitive decline after an inflammatory event such as surgery, inf

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c43129e3637b1bd9c4d5b3a29f3d42a
https://doi.org/10.1523/jneurosci.5818-10.2011

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Synaptic Correlates of Increased Cognitive Vulnerability with Aging: Peripheral Immune Challenge and Aging Interact to Disrupt Theta-Burst Late-Phase Long-Term Potentiation in Hippocampal Area CA1

Autor: Jared T. Ahrendsen, Susan L. Patterson, Ruth M. Barrientos, Timothy R. Chapman, Steven F. Maier

Publikováno v: The Journal of Neuroscience. 30:7598-7603

Variability in cognitive functioning increases markedly with age, as does cognitive vulnerability to physiological and psychological challenges. Exploring the basis of this vulnerability may provide important insights into the mechanisms underlying a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::bfb6f975488b9c76d447560a7b0f3ee3
https://doi.org/10.1523/jneurosci.5172-09.2010

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Aging and an Immune Challenge Interact to Produce Prolonged, but Not Permanent, Reductions in Hippocampal L-LTP and mBDNF in a Rodent Model with Features of Delirium

Autor: Giuseppe P. Cortese, Susan L. Patterson, Ruth M. Barrientos, Steven F. Maier, Naoto Tanaka

Publikováno v: eneuro. 5:ENEURO.0009-18.2018

Aging increases the risk of abrupt declines in cognitive function after an event that triggers immune system activation (e.g. surgery, infection, or injury). This phenomenon is poorly understood, but rodent models may provide clues. We have previousl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f0885986223a2140ddc43449a611235
https://doi.org/10.1523/eneuro.0009-18.2018

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