Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Susan L. Orrill"'
Publikováno v:
Organic Process Research & Development, 5(6), 575-580. American Chemical Society
An efficient synthesis of the PDE IV inhibitor, 9H-cyclopentyl-7-ethyl-3-(thiophen-2-yl)-pyrazolo[3,4-c]-1,2,4-triazolo-5,6-dihydro-[4,3-a]pyridine 1 is described. Starting from commercially available γ-caprolactone, the synthesis was carried out in
Autor:
Peter J. Daniels, Sally Gut, Peter J. Dunn, and Susan L. Orrill, Ralph Breitenbach, Richard A. Buzon, Lehner Richard S, Frank J. Urban, Jr.† Harry A. Watson
Publikováno v:
Organic Process Research & Development. 2:66-70
This paper describes process research leading to the successful scale-up of a potent cholesterol absorption inhibitor 4‘‘,6‘‘-bis((2-fluorophenyl)carbamoyl)hecogenyl β-O-cellobioside 3. The synthesis of 3 from hecogenyl β-O-cellobioside 4 r
Autor:
Lehner Richard S, Peter J. Daniels, Sally Gut, Richard A. Buzon, Ralph Breitenbach, H. A. Jun. Watson, Frank J. Urban, Peter J. Dunn, Susan L. Orrill
Publikováno v:
ChemInform. 29
Publikováno v:
ChemInform. 33
An efficient synthesis of the PDE IV inhibitor, 9H-cyclopentyl-7-ethyl-3-(thiophen-2-yl)-pyrazolo[3,4-c]-1,2,4-triazolo-5,6-dihydro-[4,3-a]pyridine 1 is described. Starting from commercially available γ-caprolactone, the synthesis was carried out in