Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Susan L. Hafenstein"'
Autor:
Devanshi R. Patel, Allen M. Minns, Derek G. Sim, Cassandra J. Field, Abigail E. Kerr, Talia A. Heinly, Erin H. Luley, Randall M. Rossi, Carol M. Bator, Ibrahim M. Moustafa, Elizabeth B. Norton, Susan L. Hafenstein, Scott E. Lindner, Troy C. Sutton
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 3 (2024)
ABSTRACTMultiple vaccines have been developed and licensed for severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). While these vaccines reduce disease severity, they do not prevent infection. To prevent infection and limit transmission, vac
Externí odkaz:
https://doaj.org/article/55f1a1bf25284935bbdcb7a25dab70bd
Autor:
Andrew J. Charnesky, Julia E. Faust, Hyunwook Lee, Rama Devudu Puligedda, Daniel J. Goetschius, Nadia M. DiNunno, Vaskar Thapa, Carol M. Bator, Sung Hyun (Joseph) Cho, Rahnuma Wahid, Kutub Mahmood, Scott Dessain, Konstantin M. Chumakov, Amy Rosenfeld, Susan L. Hafenstein
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-11 (2023)
Abstract Global eradication of poliovirus remains elusive, and it is critical to develop next generation vaccines and antivirals. In support of this goal, we map the epitope of human monoclonal antibody 9H2 which is able to neutralize the three serot
Externí odkaz:
https://doaj.org/article/9fd2243b86754c1196621e07354a248f
Autor:
Samantha R. Hartmann, Andrew J. Charnesky, Simon P. Früh, Robert A. López-Astacio, Wendy S. Weichert, Nadia DiNunno, Sung Hung Cho, Carol M. Bator, Colin R. Parrish, Susan L. Hafenstein
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-11 (2023)
Abstract Canine parvovirus (CPV) is an important pathogen that emerged by cross-species transmission to cause severe disease in dogs. To understand the host immune response to vaccination, sera from dogs immunized with parvovirus are obtained, the po
Externí odkaz:
https://doaj.org/article/2efb5d4d0c334371b3766473a0aa6b1f
Autor:
Daniel J. Goetschius, Samantha R. Hartmann, Suriyasri Subramanian, Carol M. Bator, Neil D. Christensen, Susan L. Hafenstein
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Abstract Human papillomavirus (HPV) is a significant health burden and leading cause of virus-induced cancers. HPV is epitheliotropic and its replication is tightly associated with terminal keratinocyte differentiation making production and purificat
Externí odkaz:
https://doaj.org/article/e04b64485e644667b0e59a3751e54ebe
Autor:
Nadia M. DiNunno, Daniel J. Goetschius, Anoop Narayanan, Sydney A. Majowicz, Ibrahim Moustafa, Carol M. Bator, Susan L. Hafenstein, Joyce Jose
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-8 (2020)
Here, the authors provide a 3.4 Å resolution structure of mature Zika virus (ZIKV) and identify two lipid moieties, coordinated by hydrophobic residues of the M and E transmembrane helices and between two helices of E protein, that play an essential
Externí odkaz:
https://doaj.org/article/7496445a4f9c45ed87e234236a9b0144
Autor:
Anna Perederina, Di Li, Hyunwook Lee, Carol Bator, Igor Berezin, Susan L. Hafenstein, Andrey S. Krasilnikov
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
Ribozyme-based RNase MRP is an essential eukaryotic enzyme involved in the maturation of rRNA and is evolutionarily related to RNase P. Here, the authors present the 3.0 Å cryo-EM structure of the S. cerevisiae RNase MRP holoenzyme, a 450 kDa ribonu
Externí odkaz:
https://doaj.org/article/06c391967b3f4eb3af021d620c244d8d
Autor:
Samantha R. Hartmann, Daniel J. Goetschius, Jiafen Hu, Joshua J. Graff, Carol M. Bator, Neil D. Christensen, Susan L. Hafenstein
Publikováno v:
Viruses, Vol 13, Iss 10, p 2023 (2021)
Human papillomavirus (HPV) is a significant health burden and leading cause of virus-induced cancers. However, studies have been hampered due to restricted tropism that makes production and purification of high titer virus problematic. This issue has
Externí odkaz:
https://doaj.org/article/fc77a8772a78492a91c40dfcca533a5e
Autor:
Matthew D Lauver, Daniel J Goetschius, Colleen S Netherby-Winslow, Katelyn N Ayers, Ge Jin, Daniel G Haas, Elizabeth L Frost, Sung Hyun Cho, Carol M Bator, Stephanie M Bywaters, Neil D Christensen, Susan L Hafenstein, Aron E Lukacher
Publikováno v:
eLife, Vol 9 (2020)
JCPyV polyomavirus, a member of the human virome, causes progressive multifocal leukoencephalopathy (PML), an oft-fatal demyelinating brain disease in individuals receiving immunomodulatory therapies. Mutations in the major viral capsid protein, VP1,
Externí odkaz:
https://doaj.org/article/49ff0ad1d7a649d79e8ecf95bda3fe2f
Autor:
Robert A. López-Astacio, Oluwafemi F. Adu, Daniel J. Goetschius, Hyunwook Lee, Wendy S. Weichert, Brian R. Wasik, Simon P. Frueh, Brynn K. Alford, Ian E.H. Voorhees, Joseph F. Flint, Sarah Saddoris, Laura B. Goodman, Edward C. Holmes, Susan L. Hafenstein, Colin R. Parrish
Publikováno v:
bioRxiv
Canine parvovirus (CPV) is a small non-enveloped single-stranded DNA virus that causes serious diseases in dogs worldwide. The original strain of the virus (CPV-2) emerged in dogs during the late-1970s due to a host range switch of a virus similar to
Publikováno v:
J Virol
Ubiquitous and abundant in ecosystems and microbiomes, gokushoviruses constitute a Microviridae subfamily, distantly related to bacteriophages ΦX174, α3, and G4. A high-resolution cryo-EM structure of gokushovirus ΦEC6098 was determined, and the a