Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Susan L. Due"'
Publikováno v:
Antimicrobial Agents and Chemotherapy. 10:630-638
The metabolic fate of the orally effective cephalosporin antibiotic cefaclor (Lilly 99638) has been studied in rats, mice, and dogs. Cefaclor is efficiently absorbed from the gastrointestinal tract as the intact antibiotic. In rats and mice, cefaclor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce3706c14ed29da5593f6e514a3d697e
https://doi.org/10.1128/aac.10.4.630
https://doi.org/10.1128/aac.10.4.630
Publikováno v:
Journal of Pharmacy and Pharmacology. 27:728-732
The disposition and metabolism of (+)- and (-)-methadone has been compared in rats. At equal molecular doses, somewhat higher plasma levels of (-)-isomer were observed. At equal analgesic doses, brain and plasma concentrations of (+)-methadone were a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f16b5f29bc60581ab17471c01d879c18
https://doi.org/10.1111/j.2042-7158.1975.tb09391.x
https://doi.org/10.1111/j.2042-7158.1975.tb09391.x
Autor:
Hugh R. Sullivan, Susan L. Due
Publikováno v:
Journal of Medicinal Chemistry. 16:909-913
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a74369a60901f9ce8b771a1905e3dab
https://doi.org/10.1021/jm00266a009
https://doi.org/10.1021/jm00266a009
Publikováno v:
Life Sciences. 12:463-473
Through the combined use of deuterium labeling and GC-MS analysis, eight urinary metabolites of d-propoxyphene have been identified in man following a single oral dose of 130 mg of d-propoxyphene. The metabolites present were: norpropoxyphene, dinorp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d567bebf470e48ddecea9229a48bdccc
https://doi.org/10.1016/0024-3205(73)90334-2
https://doi.org/10.1016/0024-3205(73)90334-2
Publikováno v:
Biomedical mass spectrometry. 3(5)
Through the combined use of stable isotope labeling and gas chromatographic mass spectrometric analysis, the metabolic patterns for propoxyphene have been determined in laboratory animals and man. The rat and dog eliminated propoxyphene and its metab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ca1af7b36a86ca5e6548d7ecef1ed3b
https://pubmed.ncbi.nlm.nih.gov/974236
https://pubmed.ncbi.nlm.nih.gov/974236
Publikováno v:
Biomedical mass spectrometry. 2(1)
Metabolism studies in the rat, dog and cat have demonstrated a definite species difference in biotransformation and elimination of alpha-1-trans-4-dimethylaminotetrahydro-3-furylcyclohexanephenylglycolate (Lilly 82537), an experimental anticholinergi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43fc64287e2476b0441f015476f552e7
https://pubmed.ncbi.nlm.nih.gov/1131394
https://pubmed.ncbi.nlm.nih.gov/1131394
Autor:
Susan L. Due, Hugh R. Sullivan
Publikováno v:
Chemischer Informationsdienst. 4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::198b59a084755f8156efdcbb0ae8c6a4
https://doi.org/10.1002/chin.197349481
https://doi.org/10.1002/chin.197349481
The biotransformation of the parenterally effective cephalosporin antibiotic cefamandole nafate (I) has been studied in rats and dogs. After rapid in vivo hydrolysis of the nafate pharmaceutical form to cefamandole (II), the antibiotic was found to b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56e4e4725121034f16d4fffd2fa6656e
https://europepmc.org/articles/PMC352156/
https://europepmc.org/articles/PMC352156/
Publikováno v:
Chemischer Informationsdienst. 3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::31e5fc5a8390d2753e8487c899122e86
https://doi.org/10.1002/chin.197233460
https://doi.org/10.1002/chin.197233460
Publikováno v:
Journal of Pharmacy and Pharmacology. 25:1009-1010
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6224e230e17029dac6d4d0e8cfa611d4
https://doi.org/10.1111/j.2042-7158.1973.tb09998.x
https://doi.org/10.1111/j.2042-7158.1973.tb09998.x